Guangxi Botanical Garden of Medicinal Plants
Guangxi Botanical Garden of Medicinal Plants
Lin C.-R.,CAS Institute of Botany |
Liu Y.,CAS Institute of Botany |
Nong D.-X.,Guangxi Botanical Garden of Medicinal Plants |
Kono Y.,Academia Sinica, Taiwan |
Peng C.-I.,Academia Sinica, Taiwan
Botanical Studies | Year: 2013
Background Aspidistra crassifila Yan Liu & C.-I Peng, a new species of the Asparagaceae from Guangxi Zhuang Autonomous Region, China, is described and illustrated. Results The new species is similar to A. subrotata Y. Wan & C. C. Huang in the perianth lobes triangular-lanceolate and horizontally spreading, but differs by the perianth campanulate, lobes with appendages at base, stamens 6-8 mm long, filaments enlarged, anthers adnate to perianth tube, connectives extended and upcurved. The chromosome number of the new species was determined to be 2n = 38, and the karyotype was formulated as 2n = 22m2SC+4sm+12st. Conclusion A careful study of the literature, herbarium specimens and living plants, both in the wild and in cultivation in the experimental greenhouse, support the recognition of the new species Aspidistra crassifila, which is described herein. Aspidistra crassifila is currently known only from Shiwandashan Mountains, which lie in southern Guangxi. A line drawing, color plates and a distribution map are given for the new species to aid in identification. © 2013 Lin et al.
Guo X.-Y.,Guangxi Botanical Garden of Medicinal Plants |
Guo X.-Y.,CAS Institute of Botany |
Huang Z.-Y.,CAS Institute of Botany |
Xu A.-C.,China Jiliang University |
Zhang X.-S.,CAS Institute of Botany
Forestry | Year: 2011
Effects of a 30-day flooding period on some morphological and physiological changes and on relative growth rate (RGR) of 13 hybrid poplar clones, belonging to four different parentages i.e. T × N, T × D, D × N and N × E (with T = Popolus trichocarpa, N = P. nigra, D = P. deltoids and E = P. euramericana) were studied under controlled conditions. Responses of the 13 clones to flooding differed, and they varied with duration of flooding period. Stomatal conductance was not reduced in any of the plants during the first few days of flooding. However, in trees of some clones, stomata opened and then closed as flooding was prolonged. Net photosynthesis rates (Pn) of flooded trees of some clones decreased during flooding, but in some flooded clones it returned to the value of the control following a period of decrease. RGR was reduced by flooding in 10 clones and was correlated with reduction of Pn. Other responses to flooding included formation of adventitious roots and relative amount of carbon allocated to the above- and below-ground tissues. Based on the dendrogram from the hierarchical cluster analysis, the 13 clones tested could be divided into two groups. Clones 58-280, DN-34, 311-93, DN-70, Simplot, R-419 and OP-367 were grouped into a cluster with high tolerance to flooding; clones 309-74, PC-1, DN-14273, 195-529, NE-353 and R-247 into a cluster with low tolerance to flooding. © Institute of Chartered Foresters, 2010. All rights reserved.
PubMed | Guangxi Botanical Garden of Medicinal Plants, Chinese Academy of Sciences, La Trobe University and Peking Union Medical College
Type: Journal Article | Journal: PloS one | Year: 2017
Taxillus chinensis (DC.) Danser, the official species of parasitic loranthus that grows by parasitizing other plants, is used in various traditional Chinese medicine prescriptions. ABA-dependent and ABA-independent pathways are two major pathways in response to drought stress for plants and some genes have been reported to play a key role during the dehydration including dehydration-responsive protein RD22, late embryogenesis abundant (LEA) proteins, and various transcription factors (TFs) like MYB and WRKY. However, genes responding to dehydration are still unknown in loranthus.Initially, loranthus seeds were characterized as recalcitrant seeds. Then, biological replicates of fresh loranthus seeds (CK), and seeds after being dehydrated for 16 hours (Tac-16) and 36 hours (Tac-36) were sequenced by RNA-Seq, generating 386,542,846 high quality reads. A total of 164,546 transcripts corresponding to 114,971 genes were assembled by Trinity and annotated by mapping them to NCBI non-redundant (NR), UniProt, GO, KEGG pathway and COG databases. Transcriptome profiling identified 60,695, 56,027 and 66,389 transcripts (>1 FPKM) in CK, Tac-16 and Tac-36, respectively. Compared to CK, we obtained 2,102 up-regulated and 1,344 down-regulated transcripts in Tac-16 and 1,649 up-regulated and 2,135 down-regulated transcripts in Tac-36 by using edgeR. Among them some have been reported to function in dehydration process, such as RD22, heat shock proteins (HSP) and various TFs (MYB, WRKY and ethylene-responsive transcription factors). Interestingly, transcripts encoding ribosomal proteins peaked in Tac-16. It is indicated that HSPs and ribosomal proteins may function in early response to drought stress. Raw sequencing data can be accessed in NCBI SRA platform under the accession number SRA309567.This is the first time to profile transcriptome globally in loranthus seeds. Our findings provide insights into the gene regulations of loranthus seeds in response to water loss and expand our current understanding of drought tolerance and germination of seeds.
PubMed | Guangxi Botanical Garden of Medicinal Plants, Shenzhen Second Peoples Hospital and Peking Union Medical College
Type: | Journal: Fitoterapia | Year: 2016
The seeds of the medicinal plant Caesalpinia sappan yielded fourteen cassane-type diterpenes, including six new rearranged ones named as caesalppans A-F (1-6). Their structures were elucidated by spectroscopic analysis and comparison with literature data. The isolated new compounds 1-6 possess lactone-type cassane diterpenoid skeleton with an oxygen bridge between C-19 and C-20, and were tested cytotoxic activity against four cancer cell lines using the MTT method.
PubMed | Guangxi Botanical Garden of Medicinal Plants, Hunan University, Guangxi University and Peking Union Medical College
Type: Journal Article | Journal: Acta pharmaceutica Sinica. B | Year: 2016
PubMed | Guangxi Botanical Garden of Medicinal Plants, Inner Mongolia Medical College, Research Institute of Organic Agriculture FIBL, Chinese Institute of Materia Medica and Texas A&M University
Type: | Journal: Journal of ethnopharmacology | Year: 2016
As a group of important medicine plants, Boschniakia rossica (Cham. et Schltdl) Fedtsch. and B. himalaica Hookfet Thoms, which are the only two species in the genus Boschniakia (Orobanchaceae), have long been used in traditional Chinese medicine for their multiple therapeutic uses related to enhanced renal function, erectile dysfunction, defaecate and hepatoprotective. Additionally, the two species are also used as dietary supplements in wine, cosmetics, and other healthy food.By providing comprehensive information and data of genus Boschniakia on botany, traditional medicinal uses, phytochemistry, pharmacological research and toxicology, this review aims to summary the group of natural compounds from Boschniakia discovered so far. The other aims are to reference research findings of their biological activities and functions in medicine, physiology, and cell biology to highlight the compound candidates which can be used for further drug discovery in several pharmaceutical areas including antioxidation, anticancer, anti-inflammation, anti-senile, and immunology.All of the available information on B. rossica and B. himalaica was collected from the electronic resources (such as PubMed, SciFinder Scholar, CNKI, TPL (www.theplantlist.org), Google Scholar, Baidu Scholar, and Web of Science).After a comprehensive analysis of the literatures from available online sources, the results show that both species of genus Boschniakia are valuable and popular herbal medicines with potentials to cure various ailments. The phytochemical studies revealed that the chemical compositions of this genus were mainly iridoid glycosides and phenylpropanoid glycosides. To date, 112 compounds have been isolated from the genus, while their crude extracts and purified compounds have been found to possess a wide range of biological activities including anti-senile, antitumor and anticancer, anti-inflammatory, protecting liver, boost memory, anti-oxidation, anti-lipid peroxidative, and antiviral activities.The existing traditional uses of the genus Boschniakia have been evaluated, and the properties of the genus are summarized based on botany, phytochemistry, pharmacological research, and toxicology. This review aims to introduce the utilization and application of the genus Boschniakia to modern drug discovery, traditional medicinal plant utilization, herbal species conservation, and the development of medicinal and health-maintaining products.
Li W.,Hanshan Normal University |
Hao J.,Guangxi Botanical Garden of Medicinal Plants |
Xiao Y.,Shantou University
Archives of Pharmacal Research | Year: 2013
Ten lupeol dicarboxylic acid monoester derivatives as new potent antitumor agents were synthesized and evaluated for in vitro antitumor activities against A549, LAC, HepG2 and HeLa cell lines. Among them, compounds 1-5 showed excellent antitumor activities against all tested tumor cell lines and compounds 6-10 exhibited high activities against A549, HepG2 and HeLa cells, exceeded lupeol, lupanol and doxorubicin. Compound 2 displayed the highest potent antitumor activities with IC50 values of 5.78 μM against A549 cell, 2.38 μM against LAC cell, 6.14 μM against HepG2 cell and 0.00842 μM against HeLa cell. © 2013 The Pharmaceutical Society of Korea.
Wang Y.,Guangxi Botanical Garden of Medicinal Plants |
Wang Y.,Inner Mongolia Medical College |
Dan Y.,Chinese Academy of Sciences |
Yang D.,Inner Mongolia Medical College |
And 10 more authors.
Journal of Ethnopharmacology | Year: 2014
Ethnopharmacological relevance Anemarrhena asphodeloides Bunge. (Asparagaceae) yields Anemarrhenae Rhizoma, which has a long history to be used as a traditional medicine to treat various ailments, like cold-induced febrile disease with arthralgia, hematochezia, tidal fever and night sweats by Yin deficiency, bone-steaming, cough, and hemoptysis. It is also used as an ingredient of healthy food, wine, tea, biological toothpaste. Its importance is demonstrated by large scale to treat kinds of diseases in eastern Asian countries. The aim of this review is to provide up-to-date information about phytochemistry, pharmacology, and toxicology of Anemarrhena asphodeloides based on scientific literatures. It will build up a new foundation for further study on mechanism and development of better therapeutic agent and healthy product from Anemarrhena asphodeloides. Material and methods All the available information on Anemarrhena asphodeloides was collected via electronic search (using PubMed, SciFinder Scholar, CNKI, TPL (www.theplantlist.org), Google Scholar, Baidu Scholar, and Web of Science). Results Comprehensive analysis of the literatures searched through sources available above confirmed that the ethnomedical uses of Anemarrhena asphodeloides had been recorded in China, Japan, and Korea for thousands of years. The phytochemical investigation revealed the presence of steroidal saponins, flavonoids, phenylpropanoids, alkaloids, steroids, organic acids, anthraquinones, and others. Crude extracts and pure compounds from Anemarrhena asphodeloides exhibited significant pharmacological effects on the nervous system and the blood system. They also showed valuable bioactivities, such as antitumor, anti-oxidation, anti-microbial, anti-virus, anti-inflammation, anti-osteoporosis, anti-skin aging and damage as well as other activities. Conclusions In light of long traditional use and modern phytochemical and pharmacological studies summarized, Anemarrhena asphodeloides has demonstrated a strong potential for therapeutic and health-maintaining purposes. Both the extracts and chemical components isolated from the plant showed a wide range of biological activities. Thus more pharmacological mechanisms on main active compounds (TBII, TAIII, mangiferin and other ingredients) are necessary to be explored. In addition, as a good source of the traditional medicine, clinical studies of main therapeutic aspects (e.g. diabetes, Alzheimers disease, Parkinsons disease, etc.), toxicity and adverse effect of Anemarrhena asphodeloides will also undoubtedly be the focus of future investigation. © 2014 Elsevier Ireland Ltd.
Cui Z.,Guangxi Botanical Garden of Medicinal Plants |
Cui Z.,Inner Mongolia Medical College |
Guo Z.,Beijing University of Chinese Medicine |
Miao J.,Guangxi Botanical Garden of Medicinal Plants |
And 5 more authors.
Journal of Ethnopharmacology | Year: 2013
Ethnopharmacological relevance: Species of the genus Cynomorium (Cynomoriaceae), including C. songaricum Rupr. and C. coccineum L.; have a long history of use in traditional medicine to treat various ailments such as impotence, premature ejaculation, kidney-yang deficiency, spermatorrhea, colic, and stomach ulcers. In addition, these species are used in health foods, tea, and cosmetics. Aim of the review: The aim of this review is to provide comprehensive information on the botany, traditional uses, phytochemistry, pharmacological research, and toxicology of C. songaricum and C. coccineum and to explore the therapeutic potential and future research opportunities of these species. Materials and methods: All available information on C. songaricum and C. coccineum was collected via electronic search (using PubMed, ACS, CNKI, Google Scholar, Baidu Scholar, and Web of Science). Results: The ethnomedical uses of C. songaricum and C. coccineum in Saudi Arabia, China, Afghanistan, Mongolia, and Iran for several types of ailments were recorded. A phytochemical investigation revealed the presence of flavonoids, terpenoids, phloroglucinol adducts, saccharides, phenylpropanoids, steroids, organic acids, and other compounds. The crude extracts and pure compounds from C. songaricum and C. coccineum exhibited a wide spectrum of in vitro and in vivo pharmacological activity, including anti-fatigue, anti-hypoxia, anti-oxidation, anti-diabetic, immune system modulating, and antiviral activity. Conclusions: Cynomorium species have emerged as a source of traditional medicine. Many studies have provided evidence for the therapeutic efficacy of these species in treating various conditions and possible mechanisms. However, further research is required for the development of new drugs and therapies for the treatment of various diseases, especially cancer and diabetes. Therefore, this review on the ethnopharmacology, phytochemistry, and toxicity of Cynomorium species will provide helpful data for further studies and commercial exploitation of the species. © 2013 Elsevier Ireland Ltd.
Shi F.,Guangxi Botanical Garden of Medicinal Plants |
Zhao X.,Guangxi Botanical Garden of Medicinal Plants |
Mo Q.,Guangxi Botanical Garden of Medicinal Plants |
Xie L.,Guangxi Botanical Garden of Medicinal Plants
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2014
OBJECTIVE: To establish an UPLC-PDA method for simultaneous determination of chlorogenic acid and luteoloside in Lonicerae Flos. On the basis of developed method, the quality of Lonicerae Flos from nine habitats and two local germplasms introduced from Qufu in Shandong to Wuming in Guangxi was evaluated.METHODS: The analysis was performed on a Waters Acquity UPLC H-Class system. An Acquity UPLC BEH RP18 (100 mm x 2.1 mm,1.7 μm) column was used for all analyses. The investigated compounds were separated with a gradient mobile phase consisting of acetonitrile and 0.4% phosphoric acid solution at a flow rate of 0.2 mL/min, and the detection wavelength was set at 242 nm.RESULTS: The quality of Lonicerae Flos from Qufu was the best among Lonicerae Flos of nine habitats for its content of chlorogenic acid and luteoloside at 35.715 and 1.270 mg/g, respectively. The content of chlorogenic acid and luteoloside in Lonicerae Flos of "Jiufengyihao" and "Shuxing" introduced from Qufu to Wuming both complied with the standard of Chinese Pharmacopoeia (2010 edition).CONCLUSION: The developed UPLC-PDA method is simple, reliable and repeatable, which is helpful for the quality control of Lonicerae Flos. "Jiufengyihao" and "Shuxing" are potential germplasms for the introduction of Lonicerae Flos in Wuming.