Jinhua, China
Jinhua, China

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PubMed | Yangzhou University, Zhejiang Normal University and Guangfu Hospital
Type: | Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | Year: 2016

This meta-analysis synthesized current evidence from 10 trials to evaluate the association between steroid therapy and osteonecrosis incidence in patients with severe acute respiratory syndrome (SARS). Our results suggest that higher cumulative doses and longer treatment durations of steroids are more likely to lead to the development of osteonecrosis in SARS patients.The link between steroid treatment and the risk of osteonecrosis in SARS patients remains unknown. The present meta-analysis aimed to examine the dose-response association between steroid therapy and osteonecrosis incidence in SARS patients. The sex differences in the development of steroid-induced osteonecrosis were also examined.We searched PubMed, Web of Science, CNKI, and WANFANG for studies that involved steroid therapy and reported osteonecrosis data in SARS patients. Two authors independently extracted the data from the individual studies, and the rate ratio (RR) of osteonecrosis was calculated using random-effect models.Ten studies with 1137 recovered SARS patients met the inclusion criteria. Close relationships between osteonecrosis incidence and both the cumulative dose and treatment duration of steroids were observed. The summary RR of osteonecrosis was 1.57 (95% confidence interval (CI) 1.30-1.89, p<0.001) per 5.0g increase in the cumulative dose of steroids and was 1.29 (95% CI 1.09-1.53, p=0.003) for each 10-day increment of increase in treatment duration. The relationship was non-linear (p SARS patients who received higher cumulative doses and longer treatment durations of steroids were more likely to develop osteonecrosis, and there were no sex differences in this dose-dependent side effect. Our findings suggest that it is important to reduce osteonecrosis risk by modifying the cumulative dose and the treatment duration of steroids in SARS patients.


Qian L.-J.,Guangfu Hospital
International Eye Science | Year: 2012

AIM: To observe the damage of 23-Gauge and 20-Gauge vitrectomy system to lens. METHODS: Between August 2009 and July 2010, 95 eyes of 91 patients suffered vitrectomy surgery. All paients were phakic. Group A contained 48 eyes of 46 patients who underwent 20-Gauge vitrectomy system. Group B contained 47 eyes of 45 patients who underwent 23-Gauge vitrectomy system. Ceiling lamp was used in 23-Gauge vitrectomy system. Epiretinal membranes peeled, retinotomy, retinal detachment attached, foreign bodies removed, retinal laser photocoagulation, air-fluid exchange, gas or/and silicone oil tamponaded and other steps were taken as needed. Whether the lenses would be damaged in the surgery was observed. RESULTS: In 20G vitrectomy group, 18 eyes had lens damaged while in 23G vitrectomy group, 5 eyes had lenses damaged, P<0.01. CONCLUSION: 23-Gauge vitrectomy system can change the tube position flexibly if necessary, reducing the damage caused by the devices during the opposite base vitreous body vitrectomy.


Hong Q.,Guangfu Hospital | Wang Y.,Zhejiang University | Wang J.,Guangfu Hospital | Hu C.,Guangfu Hospital | And 3 more authors.
National Medical Journal of China | Year: 2014

Objective: To explore the application of three-dimensional (3D) high-definition (HD) laparoscopy in radical operation for stomach carcinoma.Methods: A total of 12 cases of radical operation for stomach carcinoma were performed under 3D laparoscopy.The procedures included total gastrectomy (n =6) and distal gastrectomy (n = 6). The operative duration, intraoperative blood loss, number of lymph node harvested, postoperative first flatus day and time of food intake were recorded and analyzed.Results: All cases were successfully operated without complications.The operative duration was 180-210 min, blood loss 50 - 150 ml, number of lymph node harvested 32-54 and postoperative first faltus day 1-3 days.Also all cases could take fluids at Days 4-5 postoperation.Conclusion: 3 D laparoscopic radical operation for gastric cancer may be performed safely and effectively with decreased surgical difficulties. Copyright © 2014 by the Chinese Medical Association


Hong Q.,Guangfu Hospital | Wang Y.,Zhejiang University | Wang J.,Zhejiang University | Hu C.,Zhejiang University | And 3 more authors.
Zhonghua yi xue za zhi | Year: 2014

OBJECTIVE: To explore the application of three-dimensional (3D) high-definition (HD) laparoscopy in radical operation for stomach carcinoma.METHODS: A total of 12 cases of radical operation for stomach carcinoma were performed under 3D laparoscopy. The procedures included total gastrectomy (n = 6) and distal gastrectomy (n = 6). The operative duration, intraoperative blood loss, number of lymph node harvested, postoperative first flatus day and time of food intake were recorded and analyzed.RESULTS: All cases were successfully operated without complications. The operative duration was 180-210 min, blood loss 50-150 ml, number of lymph node harvested 32-54 and postoperative first faltus day 1-3 days. Also all cases could take fluids at Days 4-5 postoperation.CONCLUSION: 3D laparoscopic radical operation for gastric cancer may be performed safely and effectively with decreased surgical difficulties.


PubMed | Zhejiang University and Guangfu Hospital
Type: Journal Article | Journal: Zhonghua yi xue za zhi | Year: 2014

To explore the application of three-dimensional (3D) high-definition (HD) laparoscopy in radical operation for stomach carcinoma.A total of 12 cases of radical operation for stomach carcinoma were performed under 3D laparoscopy. The procedures included total gastrectomy (n = 6) and distal gastrectomy (n = 6). The operative duration, intraoperative blood loss, number of lymph node harvested, postoperative first flatus day and time of food intake were recorded and analyzed.All cases were successfully operated without complications. The operative duration was 180-210 min, blood loss 50-150 ml, number of lymph node harvested 32-54 and postoperative first faltus day 1-3 days. Also all cases could take fluids at Days 4-5 postoperation.3D laparoscopic radical operation for gastric cancer may be performed safely and effectively with decreased surgical difficulties.

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