Entity

Time filter

Source Type


Zhao H.,Guangdong Pharmaceutical College | Zha L.,Jiangxi Normal University | Cai M.,Jiangxi Normal University
Reaction Kinetics, Mechanisms and Catalysis | Year: 2010

An MCM-41-supported mercapto rhodium complex [MCM-41-SH-Rh] was conveniently synthesized from commercially available and cheap c-mercaptopropyltriethoxysilane via immobilization on MCM-41, followed by reacting with rhodium chloride. It was found that the title complex is an efficient catalyst for the hydrosilylation reaction of olefins with triethoxysilane and can be reused several times without noticeable loss of activity. © Akadémiai Kiadó, Budapest, Hungary 2010. Source


Wang Y.N.,Guangdong Pharmaceutical College
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2012

To investigate the chemical constituents from the whole herbs of Anoectochilus chapaensis. The chemical constituents were isolated and purified by repeated column chromatographies with silica gel, Sephadex LH-20 and preparative TLC. Their structures were identified by their physiochemical property and spectral data. 6 compounds were isolated and elucidated as follows: (1) Friedelin, (2) Sorghumol, (3) 5alpha, 8alpha-epidioxyergost-22-en-3beta-ol, (4) Stearic acid, (5) Octadecane and (6) Epifriedelanol. Compound (1), (2) and (4) are isolated from this plant for the first time, and compound (3), (5) and (6) are isolated from genera Anoectochilus for the first time. Source


Tang L.,University of Illinois at Urbana - Champaign | Yang X.,University of Illinois at Urbana - Champaign | Yin Q.,University of Illinois at Urbana - Champaign | Cai K.,University of Illinois at Urbana - Champaign | And 14 more authors.
Proceedings of the National Academy of Sciences of the United States of America | Year: 2014

Nanomedicines (NMs) offer new solutions for cancer diagnosis and therapy. However, extension of progression-free interval and overall survival time achieved by Food and Drug Administration-approved NMs remain modest. To develop next generation NMs to achieve superior anticancer activities, it is crucial to investigate and understand the correlation between the physicochemical properties of NMs (particle size in particular) and their interactions with biological systems to establish criteria for NM optimization. Here, we systematically evaluated the size-dependent biological profiles of three monodisperse drug-silica nanoconjugates (NCs; 20, 50, and 200 nm) through both experiments and mathematical modeling and aimed to identify the optimal size for the most effective anticancer drug delivery. Among the three NCs investigated, the 50-nm NC shows the highest tumor tissue retention integrated over time, which is the collective outcome of deep tumor tissue penetration and efficient cancer cell internalization as well as slow tumor clearance, and thus, the highest efficacy against both primary and metastatic tumors in vivo. Source


Zhao H.,Jiangxi Normal University | Zhao H.,Guangdong Pharmaceutical College | Zheng G.,Jiangxi Normal University | Hao W.,Jiangxi Normal University | Cai M.,Jiangxi Normal University
Applied Organometallic Chemistry | Year: 2010

The Stille cross-coupling reaction of organostannanes with aryl halides was achieved in the presence of a catalytic amount of MCM-41-supported mercapto palladium(O) complex (1 mol%) in DMF-H2O (9:1) under air atmosphere in good to high yields. This MCM-41-supported palladium catalyst can be reused at least 10 times without any decrease in activity. Copyright © 2009 John Wiley & Sons, Ltd. Source


Yan Y.S.,Guangdong Pharmaceutical College
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2012

To study the changes of volatile oil from different compatibility of Guizhi decoction and explore their connection. The volatile oil of Cinnamomum cassia and different compatibility of Guizhi decoction extracted by steam distillation were analyzed by GC-MS. The main components of volatile oil in Cinnamomum cassia were found in different compatibility of Guizhi decoction and they accounted the most amount of total volatile oil,but the contents of the main components were decreased, there were more components existed in different compatibility of Guizhi decoction than those in Cinnamomum cassia, the new components came from Zingiber officinale mostly. GC-MS can be used to reflect the changes of volatile oil from different compatibility of Guizhi decoction, and the result will provide some evidence for the research of regular pattern of compatibility in Guizhi decoction. Source

Discover hidden collaborations