Guangdong Food and Drug Vocational College

Guangzhou, China

Guangdong Food and Drug Vocational College

Guangzhou, China
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Liang B.-J.,Guangdong Food and Drug Vocational College | Lin Y.-J.,Sun Yat Sen University
Proceedings - 2016 8th International Conference on Information Technology in Medicine and Education, ITME 2016 | Year: 2017

This paper presents a solution of a cross platform medical image reading system which supports access medical image on mobile platform based on WEB. In the web front-end, jQuery Mobile open source library is used for interface programming and gesture recognition. In the web server side, we develop Web Service with Visual C++ program language and use DICOM-WADO protocol to convert DICOM image to JPEG image. Finally, the client browser uses AJAX technology to get the server side JPEG image in an asynchronous way and display it. Tested on the Google Android, Apple IOS and other mobile platforms, the system can display medical images, adjust the images window width and window level, zoom image and other operation etc... The results show that the system has achieved its stated design goal. © 2016 IEEE.

Jiang Y.-N.,Guangdong Food and Drug Vocational College | Mo H.-Y.,Guangzhou Medical College | Yu D.-G.,University of Shanghai for Science and Technology
International Journal of Pharmaceutics | Year: 2012

Core-sheath nanofibers prepared using coaxial electrospinning were investigated for providing biphasic drug release profiles. With ketoprofen (KET) as the model drug, polyvinylpyrrolidone and zein as the sheath polymer and core matrix, respectively, the coaxial process could be carried out smoothly and continuously without any clogging of the spinneret. Scanning electron microscopy and transmission electron microscopy observations demonstrated that the nanofibers were linear with homogeneous structure and had a clear core-sheath structure with an average diameter of 730 ± 190 nm, in which the sheath had a thickness of ca. 90 nm. Differential scanning calorimetric and X-ray diffraction analyses verified that all the components in the core-sheath nanofibers were present in an amorphous state. Attenuated total reflectance Fourier transform infrared spectra demonstrated both the sheath and core matrix had good compatibility with KET owing to hydrogen bonding. In vitro dissolution tests showed that the nanofibers could provide an immediate release of 42.3% of the contained KET, followed by a sustained release over 10 h of the remaining drug. The present study exhibited a simple and useful approach to systematically design and fabricate nanostructures using coaxial electrospinning for providing biphasic drug release profiles. © 2012 Elsevier B.V. All rights reserved.

Wu J.,Guangdong Food and Drug Vocational College | Zhang H.,University of Alberta | Guan Y.,Guangdong University of Technology
Proceedings - IEEE International Conference on Robotics and Automation | Year: 2014

An important problem in robot simultaneous localization and mapping (SLAM) is loop closure detection. Recent studies of the problem have led to successful development of methods that are based on images captured by the robot. These methods tackle the issue of efficiency through data structures such as indexing and hierarchical (tree) organization of the image data that represent the robot map. In this paper, we offer an alternative approach and present a novel method for visual loop-closure detection. Our approach uses an extremely simple image representation, namely, a down-sampled binarized version of the original image, combined with a highly efficient image similarity measure - mutual information. As a result, our method is able to perform loop closure detection in a map with 20 million key locations in about 2.38 seconds on a commodity computer. The excellent performance of our method in terms of its low complexity and accuracy in experiments establishes it as a promising solution to loop closure detection in large-scale robot maps. © 2014 IEEE.

Duan Q.,Guangdong Food and Drug Vocational College | Cao J.,Hangzhou Normal University | Zhang J.,Anhui University of Traditional Chinese Medicine
Analytical Methods | Year: 2012

In this study, a capillary electrophoresis-mass spectrometry (CE-MS) method with field-amplified sample stacking was developed to analyze and detect four hydrophilic active components (danshensu, salvianolic acid B, caffeic acid and lithospermic acid) present in many plant-derived samples, and to evaluate their antioxidant ability. The assay was performed on an uncoated fused-silica capillary of 95 cm × 50 μm I.D. and a positive voltage of 27 kV was applied. The sample was injected under pressure of 50 mbar for 3-300 s and the temperature of capillary was kept 25°C. Sheath liquid constituted of 5 mM ammonium acetate in methanol solution, flowing at 4 μL min -1, and was supplied to the CE-electrospray interface. The effects of nebulizer gas pressure, the flow rate and temperature of the drying gas, sheath liquid composition and flow rate, and sample injection length were optimized in order to obtain better performance. Utilizing the preconcentration technique, the sensitivity was enhanced by approximately 30-50 fold in terms of limits of detection compared to common hydrodynamic injection without interference from matrix coextractives. The phenolic antioxidant abilities were also determined by simple and accurate free radical spiking test. Furthermore, the method has been successfully applied to a danshen sample. This journal is © The Royal Society of Chemistry 2012.

Qiu L.,Guangdong Food and Drug Vocational College | Hu F.,South China University of Technology | Peng Y.,South China University of Technology
Carbohydrate Polymers | Year: 2013

Structure of dual modified starches, cross-linked esterified corn starch (CES) and esterified cross-linked corn starch (ECS), and product films (CEF and ECF) were characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction and scanning electron microscopy (SEM). The peak 1730 cm -1 of IR spectra confirmed the formation of ester carbonyl groups in starch matrix. The sequence of modification procedure had an impact on the final modification degree, resulting in structural differences of modified starches and starch films. Compared to native starch film (NF), CEF and ECF showed improved transparence (77.59% and 74.39% respectively) with compact structure, lower crystallinity (6.5% and 7.4% respectively). Results of mechanical test indicated that structure of ECF was more flexible than CEF, whereas tensile strength was higher in CEF. Accordingly, complex modification could be an effective method to adequate properties of starch films for specific processing requirements. © 2012 Elsevier Ltd.

Chen Q.,Guangdong Food and Drug Vocational College | Wang E.,Guangdong Food and Drug Vocational College | Ma L.,Guangdong Food and Drug Vocational College | Zhai P.,Guangdong Food and Drug Vocational College
Lipids in Health and Disease | Year: 2012

Background: Resveratrol (RSV), a naturally occurring polyphenolic stilbenoid, is known to possess potent antiatherogenic properties; however, the effect of RSV on hypercholesterolemia is not fully understood. We hypothesized that RSV decreases blood cholesterol levels through the activation of cholesterol 7α-hydroxylase (CYP7A1)-mediated bile acid synthetic pathway pathways in vitro and in vivo. Methods: In this study, we evaluated body weight, serum lipid concentrations, hepatic lipid content and the size of the bile acid pool in high-fat diet (HFD)-fed C57BL/6 J mice that were treated with RSV. In addition, we characterized the underlying mechanism of the effects of RSV in HepG2 hepatocytes by Western blot analysis. Results: RSV (200 mg/kg per day) reduced body weight and liver weight gains, improved serum lipid parameters, reduced hepatic cholesterol accumulation and increased the bile acid pool size in mice fed an HFD for 8 wks. RSV significantly increased liver expression of CYP7A1 mRNA and protein and CYP7A1 enzyme activity. Furthermore, RSV treatment upregulated CYP7A1 expression and induced liver X receptor alpha (LXRα) activation in a time- and dose-dependent manner in HepG2 cells. In addition, the specific liver X receptor alpha (LXRα) inhibitor geranylgeranyl pyrophosphate (GGPP) inhibited the RSV-induced expression of CYP7A1 in HepG2 hepatocytes. Conclusion: The beneficial effects of RSV on HFD-induced hypercholesterolemia are mediated through LXRα signaling pathways, suggesting a potential target for the prevention of dyslipidemia. © 2012 Chen et al.; licensee BioMed Central Ltd.

Jiang Y.N.,Guangdong Food and Drug Vocational College
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2010

To study the formulation optimization of epimedium flavonoids self-emulsifying drug delivery system and evaluate its effect in vitro and in vivo. Based on the degree of emulsification and emulsifying time, the formulation optimization (i.e., screening of suitable oil phases, nonionic surfactants and co-surfactants) was made by the use of determination of the solubility, orthogonal design and construction of tertiary phase diagram. The dissolution of SEDDS was measured and its pharmacokinetic in rats was measured. The experimental results revealed the optimized formulation of the self-emulsifying drug delivery system which consisted of oleic acid as oil phase, Tween-80 as nonionic surfactant, and PEG400 as co-surfactant in the proportion of 2:4:4. The dissolution of SEDDS in water was more than 85% in 25 minutes, while that of the epimedium flavonoids capsule was less than 50% in 60 minutes. Application of the optimized formulation of epimedium flavonoids self-emulsifying drug delivery system could significantly increase the solubility of epimedium flavonoids in water and improve its bioavailability.

Zhang Y.-P.,Guangdong Food and Drug Vocational College | Li C.-M.,South China University of Technology
Electronics Letters | Year: 2015

The design of a small printed slot antenna for ultra-wideband application is presented. The antenna is simply formed by an L-shaped slot embedded at the centre of the ground plane, a 50 ω microstripfed line, a rectangular slit connected with the L-shaped slot and another rectangular slit at the bottom of the ground plane. The antenna has small dimensions of 16 × 28 × 0.8 mm3. The impedance bandwidth with 10 dB return loss of the antenna is from 3.1 to 10.6 GHz, in which there is two rejected bands which cover 3.3-3.73 and 5.15-5.9 GHz. © 2015 The Institution of Engineering and Technology.

Tan X.,Guangdong Food and Drug Vocational College
MATEC Web of Conferences | Year: 2015

In order to meet the need of modern medical electronic instrument measurement and control experiment, this paper put forward a design scheme of medical electronic instrument measurement and control system based on virtual instrument technology. The system combined with virtual instrument, data acquisition and network technology, the optimization of the level of automation control of medical electronic instrument, and realizes the function of remote control, and provide good interactive interface. Through the system design makes the medical electronic instrument simulation measurement and control experiment with high utilization rate of equipment, a good share of the equipment, and the advantages of good scalability. © 2015 Owned by the authors, published by EDP Sciences.

Zhang J.H.,Guangdong Food and Drug Vocational College
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2010

To study the preparation technique of total lactone of Ginkgo controlled release pellet. Aquacoat as controlled release material, DBS as plasticizer, HPMC as diffusion promoter, the best manufacture technique was got according to the factors affecting the release of the pellet. The controlled release pellet had good release rate and achieved the aim of controlling release. The technique could be used for industrialization production.

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