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Cao H.,Electricity and Automatic | Cao H.,Lille Catholic University | Peyrodie L.,Electricity and Automatic | Peyrodie L.,Lille Catholic University | And 5 more authors.
Medical and Biological Engineering and Computing | Year: 2015

The Expanded Disability Status Scale (EDSS) is the most widely used scale to evaluate the degree of neurological impairment in multiple sclerosis (MS). In this paper, we report on the evaluation of an EDSS modeling strategy based on recurrence quantification analysis (RQA) of posturographic data (i.e., center of pressure, COP). A total of 133 volunteers with EDSS ranging from 0 to 4.5 participated in this study, with eyes closed. After selection of time delay (τ), embedding dimension (m) as well as threshold (radius, r) to identify recurrent points, several RQA measures were calculated for each COP’s position and velocity data in the mono- and multi-dimensional RQAs. Estimation results lead to the selection of the recurrence rate (RR) of the COP’s position as the most pertinent RQA measure. The performance of the models versus raw and noisy data was higher in the mono-dimensional analysis than in the multi-dimensional. This study suggests that the posturographic signal’s mono-dimensional RQA is a more pertinent method to quantify disability in MS than the multi-dimensional RQA. © 2015 International Federation for Medical and Biological Engineering


Cobbaut J.-P.,De Luniversite Catholique Of Lille | Hennion C.,Groupe Hospitalier Of Linstitut Catholique Of Lille Ghicl | Boitte P.,De Luniversite Catholique Of Lille
Journal International de Bioethique | Year: 2012

This paper aims at showing how strengthening and adapting the system of care to the needs and expectations of older people today requires a change in the way to conceive the ethical approach. If clinical ethics remains a fundamental tool of the ethical approach in order to identify and to understand the ethical issues of a geriatric practice both complex and uncertain, as well as to adequately articulate the patient's expectations, the technical quality of care and the organization of a complex support, this area of care manifests the need for an institutionalization of the ethical approach. To be relevant, legitimate and effective, the ethical approach must not only be opened to the organizational aspects of care but also be able to fit into the institutional dynamics. © ESKA. Tous droits réservés pour tous pays.


PubMed | Lille Catholic University, Heilongjiang University and Groupe Hospitalier Of Linstitut Catholique Of Lille Ghicl
Type: Journal Article | Journal: Medical & biological engineering & computing | Year: 2015

The Expanded Disability Status Scale (EDSS) is the most widely used scale to evaluate the degree of neurological impairment in multiple sclerosis (MS). In this paper, we report on the evaluation of an EDSS modeling strategy based on recurrence quantification analysis (RQA) of posturographic data (i.e., center of pressure, COP). A total of 133 volunteers with EDSS ranging from 0 to 4.5 participated in this study, with eyes closed. After selection of time delay (), embedding dimension (m) as well as threshold (radius, r) to identify recurrent points, several RQA measures were calculated for each COPs position and velocity data in the mono- and multi-dimensional RQAs. Estimation results lead to the selection of the recurrence rate (RR) of the COPs position as the most pertinent RQA measure. The performance of the models versus raw and noisy data was higher in the mono-dimensional analysis than in the multi-dimensional. This study suggests that the posturographic signals mono-dimensional RQA is a more pertinent method to quantify disability in MS than the multi-dimensional RQA.


Cao H.,Heilongjiang University | Cao H.,Lille Catholic University | Peyrodie L.,Heilongjiang University | Peyrodie L.,Lille Catholic University | And 6 more authors.
Medical and Biological Engineering and Computing | Year: 2015

The Expanded Disability Status Scale (EDSS) is the most widely used scale to evaluate the degree of neurological impairment in multiple sclerosis (MS). In this paper, we report on the evaluation of an EDSS modeling strategy based on recurrence quantification analysis (RQA) of posturographic data (i.e., center of pressure, COP). A total of 133 volunteers with EDSS ranging from 0 to 4.5 participated in this study, with eyes closed. After selection of time delay (τ), embedding dimension (m) as well as threshold (radius, r) to identify recurrent points, several RQA measures were calculated for each COP’s position and velocity data in the mono- and multi-dimensional RQAs. Estimation results lead to the selection of the recurrence rate (RR) of the COP’s position as the most pertinent RQA measure. The performance of the models versus raw and noisy data was higher in the mono-dimensional analysis than in the multi-dimensional. This study suggests that the posturographic signal’s mono-dimensional RQA is a more pertinent method to quantify disability in MS than the multi-dimensional RQA. © 2015, International Federation for Medical and Biological Engineering.


Khung S.,Lille 2 University of Health and Law | Budzik J.-F.,Groupe Hospitalier Of Linstitut Catholique Of Lille Ghicl | Amzallag-Bellenger E.,Lille 2 University of Health and Law | Lambilliote A.,Lille 2 University of Health and Law | And 3 more authors.
Insights into Imaging | Year: 2013

Langerhans cell histiocytosis (LCH) represents a disorder characterised by an abnormal accumulation of histiocytes in miscellaneous tissues. The bone is commonly affected, especially the flat bones, the spine and the long bones. Some lesions in children such as a "vertebra plana" or a solitary lytic lesion of the skull may be suggestive for LCH, whereas others can be confused with a malignant tumour or osteomyelitis. This pictorial essay presents the main usual and unusual skeletal manifestations observed in LCH. Teaching points • Osseous involvement in children with LCH is very similar to that seen in multiple myeloma. • A solitary lytic lesion of the cranial vault is a typical radiographic finding of LCH. • A vertebra plana appearance in the spine is another typical radiographic finding. • Extensive signal intensity changes within bone marrow on MRI are a helpful sign for the diagnosis. • In long bones, endosteal scalloping may be responsible for a "budding appearance". © 2013 The Author(s).

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