Guinard-Barbier S.,Groupe Hospitalier Broca Cochin Htel Dieu |
Guinard-Barbier S.,University of Paris Descartes |
Chenevier-Gobeaux C.,Groupe Hospitalier Broca Cochin Htel Dieu |
Grabar S.,Groupe Hospitalier Broca Cochin Htel Dieu |
And 16 more authors.
Biomarkers | Year: 2011
Background: Mid-regional pro-atrial natriuretic peptide (MR-proANP) increases with severity in community-acquired pneumonia (CAP). We investigated whether changes of MR-proANP correlated to bacteremia. Methods: 392 adult patients with CAP visiting emergency department from a prospective observational multicenter study. Results: MR-proANP levels increased in patients with positive bacteremia (92.8 pmol/L vs. 84.3 pmol/L, p=0.04). Performance of MR-proANP to detect bacteremia (0.60) was equivalent to CRP (0.59) but less accurate than PCT (0.69). Conclusion: MR-ANP poorly predicts bacteremia in CAP patients. © 2011 Informa UK, Ltd.