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Urbana, IL, United States

Greenville College is a liberal arts four-year school that is affiliated with the Free Methodist Church, a church with an evangelical foundation. The college is located in Greenville, Illinois, United States, located 45 miles east of St. Louis, Missouri on Interstate 70. Wikipedia.

Gower R.G.,University of Washington | Lumry W.R.,University of Texas at Dallas | Davis-Lorton M.A.,Winthrop Rheumatology | Johnston D.T.,Greenville College | Busse P.J.,Mount Sinai Medical Center
Allergy and Asthma Proceedings

Hereditary angioedema (HAE) results from mutations in the C1-esterase inhibitor (C1 INH) gene that decrease production of C1 INH or render it dysfunctional. HAE is characterized by recurrent, unpredictable, bradykinin-mediated edema of the extremities, face, genitalia, trunk, gastrointestinal tract, or upper airway. Attacks causing laryngeal edema can be fatal. Patients with HAE need medications for acute attacks; some also require prophylaxis. Management requires consideration of the patient's disease burden and effect on the patient's quality of life. This review examines an individualized approach to identifying HAE patients who may benefit from prophylaxis. A literature search was performed for HAE and prophylaxis. HAE guidelines, case reports, safety studies, and randomized, controlled clinical prophylaxis trials were selected. Authors provided cases demonstrating individualized prophylaxis. U.S. Food and Drug Administration-approved options for prophylaxis of HAE include attenuated androgens and nanofiltered C1 INH (C1 INH-nf). In other countries, pasteurized C1 INH and purified C1 INH are also available. Alternative therapies include fresh frozen plasma for preprocedural prophylaxis and antifibrinolytics for long-term prophylaxis. Attenuated androgens reduce attack frequency in many patients. Adverse effects include weight gain, virilization, increased hair growth, hypercholesterolemia, depression, and liver adenomas. C1 INH-nf reduces frequency of attacks and is well tolerated. Each patient with HAE has unique needs, based on the nature and frequency of past attacks, proximity to a medical center, occupation, and the patient's wishes. These factors should be used to create a patient-centered approach to management of HAE. Copyright © 2012, OceanSide Publications, Inc. Source

Hayes W.W.,Greenville College | Manson J.R.,Clemson University
Physical Review Letters

The energy landscape of an atomic or molecular projectile interacting with a surface is often described in terms of a corrugation function that gives the classical turning point as a function of position vector parallel to the surface. It is shown here that the relative height variation of the corrugation function for scattering of atoms under classical conditions can be determined by a measurement of the maximum intensity in energy-resolved scattering spectra as a function of surface temperature. This is demonstrated by developing a semiclassical quantum theory of atomic scattering from corrugated surfaces and then extending the theory to the classical limit of large incident energies and high surface temperatures. Comparisons of calculations with available data for Ar atom scattering determine the corrugation amplitude for a molten In surface to be about 29% of the mean interparticle spacing in the bulk liquid. © 2012 American Physical Society. Source

Zeng X.,Greenville College
Perspectives in health information management / AHIMA, American Health Information Management Association

In this study, we report on a qualitative method known as the Delphi method, used in the first part of a research study for improving the accuracy and reliability of ICD-9-CM coding. A panel of independent coding experts interacted methodically to determine that the three criteria to identify a problematic ICD-9-CM subcategory for further study were cost, volume, and level of coding confusion caused. The Medicare Provider Analysis and Review (MEDPAR) 2007 fiscal year data set as well as suggestions from the experts were used to identify coding subcategories based on cost and volume data. Next, the panelists performed two rounds of independent ranking before identifying Excisional Debridement as the subcategory that causes the most confusion among coders. As a result, they recommended it for further study aimed at improving coding accuracy and variation. This framework can be adopted at different levels for similar studies in need of a schema for determining problematic subcategories of code sets. Source

Hines I.N.,Greenville College | Grisham M.B.,Immunology and Inflammation Research Group
Journal of Clinical Biochemistry and Nutrition

Liver ischemia and reperfusion-induced injury is a major clinical complication associated with hemorrhagic or endotoxin shock and thermal injury as well as liver transplantation and resectional surgery. Data obtained from several different studies suggest that an important initiating event in the pathophysiology of ischemia and reperfusion-induced tissue injury is enhanced production of superoxide concomitant with a decrease in the bioavailability of endothelial cell-derived nitric oxide. This review will summarize the evidence supporting the hypothesis that the redox imbalance induced by alterations in superoxide and nitric oxide generation creates a more oxidative environment within the different cells of the liver that enhances the nuclear transcription factor-κB-dependent expression of a variety of different cytokines and mediators that may promote as well as limit ischemia and reperfusion-induced hepatocellular injury. In addition, the evidence implicating endothelial cell nitric oxide synthase-dependent and -independent generation of nitric oxide as important regulatory pathways that act to limit ischemia and reperfusion-induced liver injury and inflammation is also presented. ©2011 JCBN. Source

Salazar M.,Greenville College | Perez Alcazar G.A.,University of Valle
Physica A: Statistical Mechanics and its Applications

In a previous study (Salazar and Perez Alcazar, 2015) we obtained the modified Landau-Lifshitz-Gilbert equation. The modification consisted in proposing a method to convert to symmetrical the kinetic coefficients of this equation. In the present study we find the solution to the proposed equation. This solution shows that the Mx and My components of the magnetization have damped oscillations. We find the expressions for the damping coefficient and the frequency of the oscillations and show their graphs. Finally, we compare these graphs with those that correspond to the frequency of oscillations for the magnetization in the Landau-Lifshitz-Gilbert equation. © 2016 Elsevier B.V. All rights reserved. Source

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