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Ahvāz, Iran

Keikhaei B.,Ahvaz Jundishapur University of Medical Sciences | Mohseni A.R.,High institute for Research and Education in Transfusion Medicine | Norouzirad R.,Medical University of Dezful | Alinejadi M.,Great oil hospital | And 3 more authors.
European Cytokine Network | Year: 2013

Objective: This study aimed to evaluate serum levels of pro-inflammatory cytokines and TGF-β in sickle cell disease (SCD) patients, and to compare the results during vaso-occlusive crisis (VOC) or steady state (StSt) conditions. Methods: 54 SCD patients (37HbSS and 17Sβ+Thal) were enrolled in the study and evaluated in two groups as follows; group A consisted of 39 VOC patients and group B comprised 15 StSt patients. Nineteen healthy volunteers were included as controls. Circulating levels of IL-1, IL-6, IL-8, IL-17,TNF-α and TGF-β were measured using ELISA. Results: Patients in VOC showed higher mean levels of all cytokines than those found in steady-state patients, but this was only marginally significant for IL-8 levels (P = 0.08). Increased levels of TGF-β and IL-17 were found in StSt patients versus normal controls (P = 0.004 andP<0.0001 respectively).A positive correlation was observed between IL-8 and IL-17 in both groups of patients (P = 0.002 and P = 0.005 respectively). Decreased levels of TNF-α, IL-1β and IL-17 were found in hydroxyurea-treated patients. Additionally, significantly higher levels of IL-6 and IL-8 were observed in hydroxyurea-treated and untreated patients than in controls respectively (P = 0.04 and P = 0.01). Conclusions: Our findings indicate that pro-inflammatory cytokines, especially IL-8 and IL-17, could be used as related markers for assessing disease severity, and consequently therapeutic intervention.


Abdollah S.,Great oil hospital | Nariman S.,Great oil hospital | Alireza Z.,Great oil hospital | Seyedparviz S.,Great oil hospital | Behnam C.,Great oil hospital
Life Science Journal | Year: 2012

The World Health Organization (WHO) estimates that more than one-third of the World's population is infected with Mycobacterium tuberculosis. Even in the developed world, TB rates are stable at best, and actually increasing in many areas. This is due to factors such as immigration, HIV and other immunosuppressive conditions. Tuberculosis is an infectious disease that is transmitted through the air. Patients with pulmonary tuberculosis are infected in this study (39.5%) people are included. This study was performed in since 2001-2006 years in patients referred to TB Ahwaz oil industry. The numbers of Patients were 48 with diagnosed pulmonary tuberculosis and pulmonary that they were treated with drugs. 19 (39.5%) smear-positive pulmonary tuberculosis, 6 cases of scrofula (12.5%), 4 TB neck and axillary lymph nodes (20.8%), 7 cases of renal tuberculosis (14.5%) and 4 cases of TB in smear-negative patients were diagnosed.


Salmanzadeh S.,Great oil hospital | Seyedkamal M.,Great oil hospital | Bahram D.,Great oil hospital | Abdollah S.,Great oil hospital | And 3 more authors.
Life Science Journal | Year: 2012

An amputation usually refers to the removal of the whole or part of an arm/hand or a leg/foot. Amputations can occur after an injury (traumatic amputation) or deliberately at surgery. The populations covered by the oil-rich areas (99,062 people) about 5500 diabetic patients were identified. 2 years in 35 cases of amputation due to diabetes was reported that 9 of them did so were excluded. Amputations due to diabetes was 26 of 17 (65%) were related to Ahwaz, and only 12 (70%) of oil have been covered by large hospital diabetes clinic. 6 out of 12 patients (50%) patients had diabetes clinic regularly.

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