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Patent
Grace Inc and ACE Inc | Date: 2014-03-18

A bar bell comprises a plate-accepting bar that extends longitudinally between two end regions at which weight plates can be mounted, a longitudinally-extending handle positioned above the plate-accepting bar and supported by the barbell, a pair of barbell-supporting brackets positioned at respective end regions of the plate-accepting bar to stably support the barbell on a supporting surface without contact between mounted weight plates and the supporting surface, and at least one longitudinally-extending fulcrum bar affixed to the barbell in such a way that it is positioned to contact a users forearm during a bicep curl and create a lever arm vis--vis the handle that maintains the barbells center of gravity in a lagging position with respect to the users hands so as to exert enhanced resistance to the curling movement during the movement.


Patent
Grace Inc and ACE Inc | Date: 2014-03-17

A dumbbell comprises a pair of frame members, each having a lower plate-like portion and an upper stem portion. The frame members are coupled together via spacer bars. An upper spacer bar is coupled to the frames members at the stem portions, and a handle is mounted for rotation about the upper spacer bar. Two lower spacer bars positioned near the front and back of the plate-like portions of the frame members. The frame members may provide the desired weight, either through choice of material, plate thickness or both, or the frame members may be provide a basic master weight plate for the dumbbell, with additional weight being provided by the addition of one or more weight plates to each frame member. Pads are mounted about the lower spacer bars, and are positioned to contact the wrist area of a user during exercise movements. A gap is defined between the pads through which the hand of a user may inserted to grasp the dumbbell in an upside-down orientation for secure control and comfort for certain exercise movements. The dumbbell may also be manipulated by the handle or stems for certain kettlebell exercises.


Patent
Grace Inc and ACE Inc | Date: 2013-03-17

A cable attachment that permits the strap of an exercise machine to be replaced independently of the machines handle without the need for sewing machines or special tools such as crimping devices comprises a body having three juncture points arranged in a generally triangular relationship, the first point being near its top to accommodate the bodys attachment to the cable of the exercise machine, the other two juncture points lying below the first point and separated from each other by the center section of the body. The two lower junction points are configured to securely accommodate a removably-coupled handle-coupling strap, and are the locations to which the straps can be secured, preferably with a suitable knot. The two lower juncture points are configured to resist lateral slippage of the straps in order to laterally stabilize the load against which the user is working, and to accommodate knots having excellent holding strength.


Patent
Grace Inc and ACE Inc | Date: 2013-03-14

User-manipulated exercise equipment of the type utilizing a weight-plate stack comprises a stack of weight plates, of which a user-selected portion moves as a unit along a pair of guide rods in response to an exercise movement by the user. The selected portion of the stack moves with virtually no cross-wise (i.e., lateral) shifting among the plates and virtually no friction between the moving portion of the stack and the guide rods because (1) a keystone bushing below the weight plate stack provides virtually error free alignment with the guide rods by setting the non-selected portion of the stack at a highly accurate home position that resets the moving stack if it has shifted laterally during movement, even if that shift is very slight, and (2) the guide rod holed in the weight plates carry bushings which align with the bushings of the adjacent weight plates to prevent the plates within the moving portion of the stack from shifting laterally with respect to each other and thereby contacting a guide rod. Preferably, the topmost weight plate in the moving portion of the stack carries bushings forming a smaller gap with the guide rods than the bushings of the remaining weight plates so that, at worst, only the topmost plate will contact a guide rod resulting in negligible friction.


Patent
Grace Inc | Date: 2014-01-23

An approach is described that combines distinct properties of a specialized porous nitrocellulose film (PNC) with quantum nanoparticles to create an improved assay and detection sensitivity, permitting the development of a camera-based imaging system for fluorescent detection of macromolecules in microarray format. The two properties of PNC that facilitate the approach are an extraordinarily high binding capacity and a newly observed internal scattering of light. Quantum nanoparticles complement these PNC properties by providing a higher level of emitted light than the fluorescent dyes in common microarray use. Overall, the approach allows for instrument cost savings, reduced imaging time, and the ability to remotely image.


Patent
Grace Inc | Date: 2013-10-03

A portable speaker system is described. The portable speaker system includes: a waterproof enclosure; a wireless communication element; and a set of speakers. A device adapted to provide multimedia content includes: a communication module adapted to be able to be communicatively coupled to a mobile device via a communication link; a processor adapted to receive multimedia data over the communication link; and a set of output elements adapted to generate user-sensible outputs based at least partly on the received multimedia data. A multimedia playback device includes: a waterproof enclosure; a set of user interface (UI) features; a set of audio output elements; a set of audio input elements; at least one connection port; a wireless communication element; and a rechargeable battery.


Patent
Grace Inc | Date: 2015-11-03

Systems, methods, and apparatuses for microarray mixing are provided. In one embodiment, a system comprises a microarray having one or more vibration motors coupled thereto, and psuedo-random voltage signals are provided to the vibration motors to agitate the microarray. In this way, the size of a microarray mixer can be reduced while avoiding standing wave artifacts in the microarray background.


Patent
Grace Inc | Date: 2015-11-03

Methods and systems are provided for a lateral flow test device. In one example a lateral flow test device may include a housing comprising an upper first portion and a lower second portion, the lower second portion further including a planar surface, a nitrocellulose matrix strip, the strip disposed on the planar surface, and one or more ligand regions included in the strip, the ligand regions comprising one or more ligands. The strip may be formed from a liquid polymer mixture dispensed onto the planar surface via a dispensing device positioned vertically above the planar surface.


Patent
Grace Inc | Date: 2013-04-25

One embodiment of an aspect of the present invention is a method for lessening the symptoms of depression, anxiety, and post-traumatic stress disorder comprising the step of administering a therapeutically effective quantity of a cholinergic M1 receptor antagonist and a therapeutically effective quantity of one or more cholinomimetic agents to lessen the symptoms of depression, anxiety, and post-traumatic stress disorder. Typically, the cholinergic M1 receptor antagonist is selected from the group consisting of telenzepine, amytriptyline, biperiden, trihexyphenidyl, darifenacin, dicyclomine, and tiotropium. Another aspect of the present invention is directed to methods and compositions employing other therapeutic agents and combinations of therapeutic agents for emulating the theoretical pharmacological effects of the non-selective mAChR antagonist scopolamine. The invention also encompasses pharmaceutical compositions incorporating one or more therapeutic agents and a pharmaceutically acceptable carrier.


A portable speaker system includes: a waterproof enclosure; a wireless communication element; a set of speakers; and a solar cell. A device able to provide multimedia content includes: a communication module able to be able to be communicatively coupled to a mobile device via a communication link; a processor able to receive multimedia data over the communication link; a set of output elements able to generate user-sensible outputs based at least partly on the received multimedia data; and an electromagnetic charging element. A multimedia playback device includes: a waterproof enclosure; a set of user interface (UI) features; a set of audio output elements; a set of audio input elements; at least one connection port; a wireless communication element; a rechargeable battery; and a light emitting diode (LED) flashlight output.

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