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Haktanir Abul M.,Karadeniz Technical University | Abul Y.,Karadeniz Technical University | Erguven M.,Goztepe Education and Training Hospital | Karatoprak E.Y.,Goztepe Education and Training Hospital | And 2 more authors.
Pediatric, Allergy, Immunology, and Pulmonology | Year: 2014

Background: Pneumonitis, pleuritis, and pulmonary interstitial infiltration have been described in patients with juvenile idiopathic arthritis (JIA). However, the pulmonary involvement of JIA is not often clinically apparent. There are few studies based on pulmonary function in children having only a diagnosis of JIA. The aim of the present study is to determine whether children with JIA have airway resistance and flow impairments measured by easily applied interrupter technique.Method: We performed interrupter resistance (Rint) measurements in children with JIA and in healthy control subjects who had no respiratory symptoms or diseases.Results: Fifty-eight children with the diagnosis of JIA (Mean age=12.5±2.75 years; range 7-17 years) and 33 healthy subjects (Mean age=11.8±2.62 years; range 6-16 years) were included in the study. The mean value of tidal peak flow during expiration measured by the interrupter technique was significantly lower in the JIA study group (0.73±0.11 L/s) compared to the healthy control group (0.79±0.08 L/s; p=0.01). Rint values measured during inspiration (Rintinsp) and during expiration (Rintexp) were higher in the JIA study group (Rintinsp=0.28±0.16 Kpa/L/s; Rintexp=0.30±0.50 Kpa/L/s) compared to the healthy control group (Rintinsp=0.26±0.11 Kpa/L/s; Rintexp=0.23±0.08 Kpa/L/s; p>0.05). There was also a positive correlation between C-reactive protein level and median expiratory interrupter resistance (Rintexp; r=0.50, p=0.005).Conclusion: The interrupter technique is a noninvasive and feasible technique and can be used to assess airway abnormalities in children with JIA who cannot successfully complete spirometry. © 2014, Mary Ann Liebert, Inc.


Kirmizibekmez H.,Goztepe Education and Training Hospital | Guven A.,Goztepe Education and Training Hospital | Yildiz M.,Goztepe Education and Training Hospital | Cebeci A.N.,Goztepe Education and Training Hospital | Dursun F.,Goztepe Education and Training Hospital
JCRPE Journal of Clinical Research in Pediatric Endocrinology | Year: 2012

Objective: Developmental defects of the thyroid gland are the most frequent causes of permanent congenital hypothyroidism. This study aimed to investigate the epidemiological features of patients with thyroid dysgenesis (TD). Methods: Medical records of 234 patients with TD followed between the years 2008 and 2010 were evaluated retrospectively. Diagnosis was made by ultrasonography. Results: Of 234 patients, 120 (51.3%) were male and 114 (48.7%) were female. Male to female ratio was 1.08 and there were no significant differences in epidemiologic and clinical findings between girls and boys. One hundred eighty-three patients (78.2%) were diagnosed as hypoplasia, 35 (14.9%) as thyroid agenesis, 4 as ectopic thyroid gland and 12 as hemiagenesis. The mean maternal age of the group was 28.9±0.4 years (range 18 to 45 years), which is significantly higher than the recently reported mean maternal ages for Turkish women. Conclusions: Advanced maternal age was more prevalent in patients with TD. Our clinical and epidemiologic findings suggested no evidence of sexual dimorphism. ©Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing.


Ozkan N.K.,Goztepe Education and Training Hospital | Ozkan K.,Goztepe Education and Training Hospital | Cilli F.,Haydarpasa Training Hospital | Esemenli T.,Marmara University
Techniques in Orthopaedics | Year: 2010

Hallux rigidus is a mild to severe degenerative arthritis of the first metatarsophalangeal joint of the foot. The symptoms usually result from cartilage wear, altered joint mechanics, and osteophyte formation particularly on the dorsal aspect of the first metatasal head. Although cheilectomy is used with predictable success to treat grade 1 and grade 2 cases with Hallux rigidus, arthrodesis is the most commonly used tecnique to treat the advanced cases. In this report, we aimed to present a new tecnique of distal metatarsal ostetomy for surgical correction of advanced hallux rigidus with cheilectomy. © 2010 by Lippincott Williams & Wilkins.


PubMed | Goztepe Education and Training Hospital
Type: Journal Article | Journal: Journal of clinical research in pediatric endocrinology | Year: 2012

Developmental defects of the thyroid gland are the most frequent causes of permanent congenital hypothyroidism. This study aimed to investigate the epidemiological features of patients with thyroid dysgenesis (TD).Medical records of 234 patients with TD followed between the years 2008 and 2010 were evaluated retrospectively. Diagnosis was made by ultrasonography.Of 234 patients, 120 (51.3%) were male and 114 (48.7%) were female. Male to female ratio was 1.08 and there were no significant differences in epidemiologic and clinical findings between girls and boys. One hundred eighty-three patients (78.2%) were diagnosed as hypoplasia, 35 (14.9%) as thyroid agenesis, 4 as ectopic thyroid gland and 12 as hemiagenesis. The mean maternal age of the group was 28.9 0.4 years (range 18 to 45 years), which is significantly higher than the recently reported mean maternal ages for Turkish women.Advanced maternal age was more prevalent in patients with TD. Our clinical and epidemiologic findings suggested no evidence of sexual dimorphism.

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