Pantnagar, India

Govind Ballabh Pant University of Agriculture and Technology is the first agricultural university of India. It was inaugurated by Jawahar Lal Nehru on 17 November 1960 as the Uttar Pradesh Agricultural University . Later the name was changed to Govind Ballabh Pant University of Agriculture and Technology in 1972 in memory of the first Chief Minister of Uttar Pradesh and statesman Pandit Govind Ballabh Pant. The University was declared as the best among all the other State Universities in India, in 1997. The University lies in the campus-town of Pantnagar in the district of Udham Singh Nagar in the state of Uttarakhand. The university is regarded as the harbinger of Green Revolution in India. Wikipedia.

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Pandey R.,Forest Health Services | Mishra A.,Govind Ballabh Pant University of Agriculture & Technology
Applied Biochemistry and Biotechnology | Year: 2010

The antibacterial activity of Aloe barbadensis was tested on clinically isolated bacterial pathogens i.e. Enterococcus bovis, Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Proteus mirabilis, Pseudomonas aeruginosa, Morganella morganii, and Klebsiella pneumoniae causing infection in human being. Ethanolic and aqueous extracts were used for the antibacterial effect, which was measured by the appearance of zone of inhibition. Relatively higher MIC concentrations were obtained for gram negative bacteria E. coli and K. pneumoniae, with ethanol extract; however, no inhibitory effect was noted for aqueous extract. Ethanolic extract possesses great inhibitory activity for gram positive bacteria, E. bovis followed by S. aureus. Among gram negative bacteria, highest inhibitory effect was observed with P. aeruginosa, followed by M. morganii, P. mirabilis, and P. vulgaris, which was significant (p∈<∈0.01) than E. coli and K. pneumoniae. Antimicrobial activity tests of crude extract of A. barbadensis were carried out to validate the use of traditional medicinal herbal and results of this study tend to give credence to the common use of A. barbadensis gel and leaf. © 2009 Humana Press.

Parakh N.,Govind Ballabh Pant University of Agriculture & Technology | Bhargava B.,All India Institute of Medical Sciences
American Journal of Cardiovascular Drugs | Year: 2011

The importance of heart rate in human health and disease has been well known to clinicians for quite some time. Recent epidemiologic studies have further strengthened this concept. Modulation of heart rate by pharmacologic as well as non-pharmacologic means has affected cardiovascular mortality and morbidity in various trials and observational studies. Conventional rate-control agents, such as β-adrenoceptor antagonists (β-blockers), calcium channel blockers, and digoxin, have contributed greatly to the management of various diseases where heart-rate reduction is required; however, these agents have effects beyond rate control that may be unacceptable.Ivabradine has recently been recognized as a pure heart-rate-reducing agent and is being extensively studied. It is the latest addition to the class of drugs used to control angina. It is indicated in cases of β-blocker intolerance or when β-blockers fail to achieve a heart rate of <60 beats/min. The pure heart-rate-reducing effect of ivabradine has also been reported in smaller studies and anecdotal case reports. The theoretical possibilities of the utility of ivabradine are many and have opened up a whole new field of research for the future. The BEAUTIFUL trial enrolled approximately 10000 patients with coronary artery disease (CAD) and left ventricular dysfunction, with the aim of assessing the effect of ivabradine versus atenolol on various cardiovascular outcomes. Although ivabradine failed to achieve favorable results for primary endpoints, it appeared effective in achieving a favorable secondary endpoint in a subgroup of patients who had a heart rate of >70 beats/min. Other large trials are also underway to assess the effects of ivabradine on heart failure, acute coronary syndromes, CAD, and other cardiovascular disorders. In this review, we discuss the pharmacologic basis of the action of ivabradine and its role in angina control, as well as in other conditions being actively studied or in which a role for ivabradine has been hypothesized. © 2011 Adis Data Information BV. All rights reserved.

Rawat R.,Govind Ballabh Pant University of Agriculture & Technology | Tewari L.,Govind Ballabh Pant University of Agriculture & Technology
Extremophiles | Year: 2012

In the present investigation, a microorganism hydrolyzing carboxymethylcellulose (CMC) was isolated and identified as Bacillus subtilis strain LFS3 by 16S rDNA sequence analysis. The carboxymethylcellulase (CMCase) enzyme produced by the B. subtilis strain LFS3 was purified by (NH 4) 2SO 4 precipitation, ion exchange and gel filtration chromatography, with an overall recovery of 15%. Native-PAGE analysis of purified CMCase revealed the molecular weight of enzyme to be about 185 kDa. The activity profile of CMCase enzyme showed the optimum activity at temperature 60 °C and pH 4.0, respectively. The enzyme activity was induced by Na +, Mg 2+, NH 4 +, and EDTA, whereas strongly inhibited by Hg 2+ and Fe 3+. The purified enzyme hydrolyzed CMC, filter paper, and xylan, but not p-nitrophenyl β-d-glucopyranoside and cellulose. Kinetic analysis of purified enzyme showed the K m value of 2.2 mg/ml. Thus, acidophilic as well as thermophilic nature makes this cellulase a suitable candidate for current mainstream biomass conversion into fuel and other industrial processes. © 2012 Springer.

Rana G.,Govind Ballabh Pant University of Agriculture & Technology | Johri U.C.,Govind Ballabh Pant University of Agriculture & Technology
Journal of Alloys and Compounds | Year: 2013

Nanocrystalline NixFe1xFe 2O4 (x = 0.0, 0.1, 0.2, 0.3 and 0.5) ferrite samples with particle size 8-16 nm were synthesized by chemical co-precipitation method. X-ray diffraction pattern confirms their inverse spinel structure. The Ni 2+ ions occupy T-site also and the cation distribution of Ni xFe1xFe2O4 changes. The change in cation inversion is indicated by the Raman spectroscopy and X-ray diffraction results, which modifies the properties of NixFe 1xFe2O4 ferrite samples in a different way than that was expected without cation inversion. The Ni-substitution should decrease the lattice parameter and the magnetization but in the present case the lattice constant as well as magnetization value both is observed to increase. © 2013 Elsevier B.V. All rights reserved.

Gope P.C.,Govind Ballabh Pant University of Agriculture & Technology | Thakur A.,Govind Ballabh Pant University of Agriculture & Technology
Fatigue and Fracture of Engineering Materials and Structures | Year: 2011

In this paper, the interaction between multiple cracks in crack growth direction is studied in an aluminium alloy under static and fatigue loading. Self similar as well as non-self-similar crack growth has been observed which depends on the relative crack positions defined by crack offset distance and crack tip distance. On the basis of experimental observations, the criterion for crack coalescence and crack growth direction are expressed in terms of the crack positions defined by crack offset and crack tip distances. The criterion presented in this study can be used to determine the limiting value of crack tip and crack offset distance and to determine the mode in which cracks coalesce during their growth process. Experimental results and crack interaction criterion presented under various crack positions and size conditions could be used to derive a new evaluation method of crack growth in multiple crack geometry. © 2011 Blackwell Publishing Ltd.

Banerjee T.,Govind Ballabh Pant University of Agriculture & Technology | Singh S.B.,Govind Ballabh Pant University of Agriculture & Technology | Srivastava R.K.,Govind Ballabh Pant University of Agriculture & Technology
Atmospheric Research | Year: 2011

Ambient air quality in respect of SO2, NO2 and total suspended particulate matter (TSPM) was monitored at Pantnagar, India from May, 2008 to April, 2009 and statistically analyzed with meteorological variables such as relative humidity (RH), wind speed (WS), precipitation (P) and mean air temperature (T). TSPM was found to be the major air pollutant causing significant deterioration of air quality with annual mean concentrations of 280μg/m3. Further, weekly mean air pollutant concentrations were statistically analyzed through stepwise multiple linear regression analysis in respect of independent meteorological variables to develop suitable statistical models. Both NO2 and TSPM concentrations were found to have been influenced by meteorological variables with coefficient of determination (R2) of 82.21 and 92.84%, respectively. However, atmospheric SO2 revealed only 22.87% of dependencies on meteorological variables. Partial correlation coefficients revealed that wind speed has the maximum influence (77.80 and 31.50%) on proposed equations for NO2 and SO2, closely followed by weekly mean temperature (73.60 and 24.30%). However, in case of TSPM, individual contribution of ambient temperature (94.40%) was found maximum, followed by relative humidity (86.50%). Model performances were evaluated through both quantitative data analysis techniques and statistical methods. Nearly 98 and 95% of potential error has been explained by the model developed for TSPM and NO2, while in case of SO2, it is found as only 61%. Therefore, performances of models (for TSPM and NO2) to predict ambient weekly mean concentrations based on forecasted weather parameters were found to be excellent, however, performance of model developed for SO2 was found only satisfactory. © 2010 Elsevier B.V.

Marla S.S.,Govind Ballabh Pant University of Agriculture & Technology | Singh V.K.,Banaras Hindu University
Functional and Integrative Genomics | Year: 2012

Plant Lipoxygenases (LOX) are known to play major role in plant immunity by providing front-line defense against pathogen-induced injury. To verify this, we isolated a full-length OsLOX3 gene and also 12 OsLOX cDNA clones from Oryza sativa indica (cultivar Pusa Basmati 1). We have examined the role played by LOXs in plant development and during attack by blast pathogen Magnaporthe grisea. Gene expression, promoter region analysis, and biochemical and protein structure analysis of isolated OsLOX3 revealed significant homology with LOX super family. Protein sequence comparison of OsLOXs revealed high levels of homology when compared with japonica rice (up to100%) and Arabidopsis (up to 64%). Isolated LOX3 gene and 12 OsLOX cDNAs contained the catalytic LOX domains much required for oxygen binding and synthesis of oxylipins. Amino acid composition, protein secondary structure, and promoter region analysis (with abundance of motifs CGTCA and TGACG) support the role of OsLOX3 gene in providing resistance to diseases in rice plants. OsLOX3 gene expression analysis of root, shoot, flag leaf, and developing and mature seed revealed organ specific patterns during rice plant development and gave evidence to association between tissue location and physiological roles played by individual OsLOXs. Increased defense activity of oxylipins was observed as demonstrated by PCR amplification of OsLOX3 gene and upon inoculation with virulent strains of M. grisea and ectopic application of methyl jasmonate in the injured leaf tissue in adult rice plants. © Springer-Verlag 2012.

Tandon S.,Govind Ballabh Pant University of Agriculture & Technology
Pestology | Year: 2012

Due to continuous use of single pesticides for controlling pests in rice and wheat, residue build up of these pesticides in environment and crop were observed. Residue analysis in grain, straw and soil treated with isoproturon and butachlor at recommended rate were done by HPLC in rice- wheat cropping system for continuous nine years at harvest time. Non detectable residue of both herbicides was found in soil, grain and straw samples at harvest every year. The limit of detection for both pesticides was 0.001 μg/g.

Shukla K.,Govind Ballabh Pant University of Agriculture & Technology | Srivastava S.,Govind Ballabh Pant University of Agriculture & Technology
Journal of Food Science and Technology | Year: 2014

The present study was undertaken to develop finger millet incorporated noodles for diabetic patients. Finger millet variety VL-149 was taken. The finger millet flour and refined wheat flour (RWF) were evaluated for nutrient composition. The finger millet flour (FMF) was blended in various proportions (30 to 50%) in refined wheat flour and used for the preparation of noodles. Control consisted of RWF noodles. Sensory quality and nutrient composition of finger millet noodles was evaluated. The 30% finger millet incorporated noodles were selected best on the basis of sensory evaluation. Noodles in that proportion along with control were evaluated for glycemic response. Nutrient composition of noodles showed that 50% finger millet incorporated noodles contained highest amount of crude fat (1.15%), total ash (1.40%), crude fiber (1.28%), carbohydrate (78.54%), physiological energy (351.36 kcal), insoluble dietary fiber (5.45%), soluble dietary fiber (3.71%), iron (5.58%) and calcium (88.39%), respectively. However, control RWF noodles contained highest amount of starch (63.02%), amylose (8.72%) and amylopectin (54.29%). The glycemic index (GI) of 30% finger millet incorporated noodles (best selected by sensory evaluation) was observed significantly lower (45.13) than control noodles (62.59). It was found that finger millet flour incorporated noodles were found nutritious and showed hypoglycemic effect. © 2011 Association of Food Scientists & Technologists (India).

Datta S.N.,Govind Ballabh Pant University of Agriculture & Technology
Aquaculture | Year: 2011

Comparative study was conducted to examine growth rate, biomass production and proximate composition of six different Azolla species. Essential amino acids (EAA) of different Azolla species in linear growth phase also analysed. A feeding trial was conducted in the cemented tanks (8.0. m. ×. 1.25. m. ×. 1.0. m) to examine efficacy of dried Azolla mixture as a feed ingredient in the diet of Labeo rohita. Azolla mixture was incorporated in diet at 15%, 25% and 35% level. Highest weight gain was recorded with the diet containing 25% Azolla mixture with specific growth rate of 0.7468% / day. The experimental fish recorded the value of exponent 'b' in the range of 2.5155 to 2.7760. The condition factor 'K' of all experimental fish was above 1.0 (1.2237-1.2326) indicating good condition of experimented fish. Incorporation of Azolla in the fish diets reduced the fat content in muscle of fish. © 2010 Elsevier B.V.

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