Government Siddha Medical College

Palayamkottai, India

Government Siddha Medical College

Palayamkottai, India
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Anbu N.,Government Siddha Medical College | Musthafa M.D.,Government Siddha Medical College | Velpandian V.,Government Siddha Medical College
International Journal of Toxicological and Pharmacological Research | Year: 2012

Diabetes mellitus is a heterogeneous disorder of carbohydrate, protein and fat metabolism in which sugars in the body are not oxidized to produce energy due to lack of pancreatic hormone insulin leads to disturbances of the acid base balance. There are two types. Type 1 (IDDM) patients have little or no ability to produce the hormone and are entirely dependent on insulin, whereas Type II (NIDDM) results from inadequate production of insulin which can be controlled by the oral hypoglycemic drugs. Aavaraiyathi churnam is one of the herbal based Siddha anti diabetic formulation for Type II maturity onset diabetes mellitus. The present study was aimed to evaluate the anti diabetic activity of polyherbal formulation Aavaraiyathi churnam in alloxan induced diabetic rats. Diabetic wistar albino rats were treated with standard drug glibenclamide and trial drug Aavaraiyathi churnam in two different doses 100mg and 200 mg. Hypoglycemic effect was evaluated in these rats and the efficacy of the trial drug was compared to the standard drug Glibenclamide. Oral administration of Aavaraiyathi churnam for 21 days in alloxan induced diabetic rats. At the end of the study period blood glucose level and body weight were statistically analyzed. Based on these results Aavaraiyathi churnam produced a significant reduction in blood glucose levels and increased in body weight when compared with non treated diabetic rats. So the present research work was confirmed that the polyherbal formulation Aavaraiyathi churnam possess hypoglycemic effect significantly.

Ayyasamy S.,Government Siddha Medical College | Sudha R.,Government Siddha Medical College
International Journal of Research in Ayurveda and Pharmacy | Year: 2013

Siddha system of medicine is one of the ancient living systems of healing in southern India. A vast cornucopia of different dosage forms of inorganic formulations are indicated in classical texts of this system. Chunnam is one such, highly acclaimed dosage form of alkaline group of drugs indicated for chronic degenerative diseases. Highly commended medicine in Siddha classics, muppu chunnam also falls under this category which is used in kayakalpam treatment. A detailed review is made in this article regarding the special features of chunnam preparations, its comprehensive uses in drug making and therapeutic effects which makes this dosage form as an indispensible one in Siddha medicine. This paper aims to highlight an important thrust area of Siddha medicine which enables to unearth many possible medicines for life style disease of this millennium. © 2010 IJRAP.

Chitra S.,Government Siddha Medical College | Sivaranjani K.,National Institute of Siddha Tambaram sanatorium
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2012

Tobacco or Pugailai (Nicotiana tobaccum) has a long history of use by medical herbalist for assorted maladies. Tobacco is probably the only plant which is ever used as the panaceas of panaceas. It was once consider to be one of the god sent remedies. But now it has become the subject of controversy because of addictive tendency of Nicotine present in it. Tobacco leaves have proven Antispasmodic, diuretic, expectorant and sialogogue actions. But its medicinal value has been abstained because of its virtue. As an antiphon a natural method of extracting Pugayillai Uppu has been procured from the Siddha literatures. Literary cue also go in league with the above mentioned pharmacological actions. This is just a prefratory attempt to compare the presence and level of the alkaloid nicotine in Pugailai uppu with that of the dry leaf powder. When this Pugailai Uppu affirmed to have less or no nicotine it will be a preponderant medicine to the society.

Shyamala K.,Government Siddha medical college
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2012

Mandura chenduram (Ferroso ferric oxide) a traditional siddha medicine has been used for centuries as a Hematinic and used to treat diseases such as Anemia, Amenerrohea, Dysmenerrohea, Menorrhagia, Diarrohea and many other gastrointestinal problems. The present work was undertaken to evaluate the Hepatoprotective action and haematinic activity of Chenduram because of the apprehension about herbometallic preparations widely used in Indian system of medicine.

Bhanumathi V.,Government Siddha Medical College
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2012

The present study was aimed to evaluate the efficacy and safety of Chitrarathai chooranam (Alpinia officinarum Hance), a Siddha drug, in patients suffering from Valiazhal Keelvayu (Rheumatoid Arthritis-RA). This was a randomized clinical trial conducted among 51 patients of either sex, with clinical and radiological evidence of RA for a period of 48 days. At the end of study period, 70 % patients showed marked to moderate improvement over their pretreatment symptom score. However, there was no significant improvement in the radiographic images. This study indicates that in the management of mild-to-moderate RA, Chitrarathai chooranam (Alpinia officinarum) is an effective and safer alternative for long-term use.

Velpandian,Government Siddha Medical College | Anbu J.,Vels University | Prema S.,Tamil University
International Journal of Pharma and Bio Sciences | Year: 2013

The Kodi Pavala Chunnam (KPC) is traditionally used in Siddha system. The present investigation was evaluated the hepatoprotective activity KPC against carbon tetrachloride (CCl4) induced liver damage in wistar rats. The KPCwas used 100 mg/kg and 200 mg/kg administered orally to the animals. The Silymarin (100 mg/kg) was given as reference standard. The KPC was effective in protecting the liver against the injury as there was significant produced action in wetliver weight, Liver volume, Direct and total bilirubin, SGPT, SGOT, ALP, Total protein, Cholesterol, Triglyceride, CAT, SOD, LPO.

Sutha S.,Government Siddha Medical College | Mohan V.R.,Ethnopharmacology Unit | Kumaresan S.,Tamil University | Murugan C.,Botanical Survey of India | Athiperumalsami T.,Ethnopharmacology Unit
Indian Journal of Traditional Knowledge | Year: 2010

The study has been carried out in Kalakad-Mundanthurai Tiger Reserve of Western Ghats, Tirunelveli, Tamil Nadu. Kanikkar, the predominant tribal community has their settlements in different areas in the Reserve Forest. Fifty medicinal plants belonging to 36 families are identified which have been employed by the tribal community for the treatment of rheumatism. The plants have been enumerated with botanical names followed by family name, local (Kanikkar) name, plant parts used, mode of administration and uses.

Thomas W.,Government Siddha Medical College | Merish S.,Government Siddha Medical College | Tamizhamuthu M.,Government Siddha Medical College
International Journal of Pharmacognosy and Phytochemical Research | Year: 2014

'Food as Medicine' is one of the basic concepts of Traditional Siddha Indian Medicine. The household recipes containing greens are part of Tamil culture. Even today one can find preparations containing greens (Keerai in Tamil) in the regular diet of south Indians. This tradition is passed through generations because of the immense medicinal properties which the greens posses. Among the frequently consumed greens Ponnankanni (Sessile joyweed - Alternanthera sessilis) finds an important place in Traditional Siddha Medical literatures. The specialty begins with its Tamil name which indicates 'Ponnankanni - Pon aagum kaan nee' (Literally meaning - Your body will get golden luster). According to Traditional Siddha literatures, this herb contains gold and thereby comes under Kaya Kalpa (Panacea) category also. Besides it is also rich in anti-oxidants, Sterol compounds, gives cooling effect to eyes & body, relieves neuritis, treats 96 types of eye diseases and aids disease free healthier life. This review paper gives an overview of all aspects of Alternanthera sessilis including botanical, phyto-chemical, Pharmacognosy and medicinal uses with reference to Siddha Indian Medicine.

Sutha S.,Government Siddha Medical College | Kalpana Devi V.,Ethnopharmacology Unit | Mohan V.R.,Ethnopharmacology Unit
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2012

Alstonia venenata R.Br. (Apocynaceae) known to the Kanikkar as "Malaivaathamudakki" is an important medicinal plant. The Kanikkar tribe, inhabitants of KMTR, Western Ghats, Tamil Nadu use this plant to get relief from rheumatic pain. The present investigation deals with GC-MS analysis of ethanol extract of the above said plant. Twenty three compounds were identified.

Alagammal M.,Government Siddha Medical College | Nishanthini A.,Ethnopharmacology Unit | Mohan V.R.,Ethnopharmacology Unit
Journal of Applied Pharmaceutical Science | Year: 2012

The ethanol extract of Polygala rosmarinifolia whole plant (Family: Polygalaceae) was investigated for its antihyperglycemic and antihyperlipidaemic effect in Wistar Albino rats. Diabetes was induced inAlbino rats by administration of alloxan monohydrate (150mg/kg, i.p).The ethanol extracts of Polygala rosmarinifolia at a dose of 100 and 200mg/kg of body weight were administered at single dose per day to diabetes induced rats for a period of 14 days. The effect of ethanol extract of Polygala rosmarinifolia whole plant extract on blood glucose, serum insulin, urea, creatinine, glycosylated haemoglobin, serum lipid profile [total cholesterol (TC), triglycerides (TG), low densitylipoprotein - cholesterol (LDL-C), very low density lipoprotein-cholester (VLDL-C), high density lipoprotein - cholesterol (HDL-C) and phospholipid (PL)] serum protein, albumin, globulin, serum enzymes [serum glutamate pyruvate transaminases (SGPT), serum glutamate oxaloacetate transaminases (SGOT), and alkaline phosphatase (ALP)], were measured in the diabetic rats. The ethanol extract of Polygala rosmarinifolia whole plant elicited significant reductions of blood glucose (P<0.05), lipid parameters except HDL-C, serum enzymes and significantly increased HDL-C. The extracts also caused significant increase in serum insulin (P<0.05) in the diabetic rats. From the above results, it is concluded that ethanol extract of Polygala rosmarinifolia possesses significant antihyperglycemic and antihyperlipidaemic effects in alloxan induced diabetic rats.

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