Government of Maharashtra

Navi Mumbai, India

Government of Maharashtra

Navi Mumbai, India

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Borkar R.R.,Government of Maharashtra
Composites: Mechanics, Computations, Applications | Year: 2014

The present study deals with the flexural analysis of single-layer fibrous composite beams using several displacement-based shear deformation theories. The theories accounts for the parabolic variation of shear stress through the thickness of a beam, so that the shear correction factor is not needed. The number of unknown variables in all the theories is the same as in the first-order shear deformation theory. These theories utilize displacement models which contain polynomial, trigonometric, hyperbolic, and exponential functions in terms of the thickness coordinate to represent the displacement variation across the thickness. A unified displacement field is used to represent all the theories. The governing differential equations and associated boundary conditions are obtained by using the principle of virtual work. A static flexural analysis is carried out for simply supported fibrous composite beams subjected to different mechanical loadings. The results obtained using all the theories are compared with those obtained by exact elasticity solution for a sinusoidal load and then their validity is checked for other loading conditions. © 2014 by Begell House, Inc.


Pise A.T.,Government of Maharashtra
2014 International Conference on Advances in Engineering and Technology, ICAET 2014 | Year: 2014

In this paper, bubble dynamics in pool boiling heat transfer using saturated water and aqueous Ammonium Chloride (anionic surfactant) solution has been studied experimentally. The concentration of surfactant was taken 2600 ppm (Parts per Million). Single bubble is generated using right angle needle tip of a hypodermic needle as a nucleation site. The bubble dynamics was studied using SONY Cyber-shot DSC-H100 camera operating at 30 frames per second at atmospheric pressure. Bubble growth in saturated water is compared surfactant solution. The result shows that, at low heat flux (q= 235 KW/m2), the bubble diameter, bubble height and bubble volume in surfactant solution approximately similar to that of water. At high heat flux (q= 738 kW/m2), the departure diameter of water bubbles was approximately same. But, in surfactant solution, the departure diameter decreases with increasing heat flux and thereby enhances pool boiling heat transfer coefficient. The enhancement is observed due to surface tension of the aqueous solution. The effect of surfactant on bubble release frequency is also discussed. © 2014 IEEE.


Pathan A.R.,University of Arkansas for Medical Sciences | Karwa M.,Auriga Research Ltd | Pamidiboina V.,Ranbaxy Laboratories | Deshattiwar J.J.,Government of Maharashtra | And 9 more authors.
Inflammopharmacology | Year: 2010

The present study was designed to evaluate, P2026 [(2-((2-(nitrooxy)ethyl) disulfanyl)ethyl 2-(2-(2,6-dichlorophenylamino)phenyl)acetate)], a novel NO (nitric oxide) donor prodrug of diclofenac for its ability to release NO and diclofenac, and whether P2026 provides advantage of improved activity/gastric tolerability over diclofenac. Oral bioavailability of P2026 was estimated from plasma concentration of diclofenac and nitrate/nitrite (NOx). Anti-inflammatory activity was evaluated in three different models of inflammation: acute (carrageenan-induced paw oedema), chronic (adjuvant-induced arthritis), and systemic (lipopolysaccharide-induced endotoxic shock). Gastric tolerability was evaluated from compound's propensity to cause gastric ulcers. P2026 exhibited dose-dependent diclofenac and NOx release. Similar to diclofenac, P2026 showed potent anti-inflammatory activity in acute and chronic model, whereas it improved activity in systemic model. Both diclofenac and P2026 inhibited gastric prostaglandin, but only diclofenac produced dose-dependent haemorrhagic ulcers. Thus, the results suggest that coupling of NO and diclofenac contribute to improved gastric tolerability while retaining the anti-inflammatory properties of diclofenac. © 2010 Springer Basel AG.


Dhumal R.,National Health Research Institute | Patil P.,Government of Maharashtra | Selkar N.,National Health Research Institute | Chawda M.,Shree Dhooptapeshwar Ayurvedic Research Foundation | And 2 more authors.
Toxicology International | Year: 2013

Objective: The present study was undertaken to determine target organ safety of «Immuforte» to establish relationship between dose or exposure and response and also to identify potential parameters for monitoring adverse effects of «Immuforte» in clinical studies, if any. Materials and Methods: A total of 40 males and 40 females were randomly assigned to the four groups, namely group I (vehicle control; gum acacia), group II (120 mg/kg BW of Immuforte in gum acacia), group III (360 mg/kg BW of Immuforte in gum acacia), and group IV (600 mg/kg BW of Immuforte in gum acacia) consisting of 10 males and 10 females in each group. Additionally, a recovery group (600 mg/kg BW of Immuforte in gum acacia) containing 5 males and 5 females was included. Results: The results showed significant decrease in percent lymphocyte count of high and mid dose groups as compared to control group. The percent neutrophil counts in all the three treated groups of male and female rats were found to be significantly higher than that of control group (P < 0.05). In females MCV values in low dose and mid dose were significantly higher as compared to control (P < 0.05). The males from low dose group showed significant decrease in total serum protein, globulin, electrolytes, direct bilirubin, creatinine levels, whereas in mid dose group along with albumin, globulin. A significant decrease in AST and cholesterol was observed. In females, significant decrease was observed in total protein and globulin of low dose and mid dose of Immuforte-treated rats (P < 0.05). Though few hematological and biochemical parameters were different from control group, no does related response was observed and further, all these values were comparable with historical control data of the colony. Terminal body weight, organ weight, gross, and histopathology did not reveal any toxicity-related any adverse effects. Heavy metal analysis of the blood samples collected from terminally sacrificed animals did not show presence of heavy metals viz. lead (Pb), mercury (Hg), cadmium (Cd), and arsenic (As). Conclusion: The results of the present study demonstrated that Immuforte does not cause any observable toxicity at doses used in the study when administered for the period of 90 days and is safe for the human use and thus, Immuforte could be used safely for therapeutic use in humans.


News Article | November 18, 2016
Site: www.prnewswire.co.uk

The Water Supply and Sanitation Collaborative Council (WSSCC) today kicks off a Sanitation Action Summit in partnership with Global Citizen India, the Government of India, Swachh Bharat Mission (SBM), and the Government of Maharashtra, to accelerate progress on sanitation and hygiene by giving voice to the needs of India's most vulnerable citizens. "Government needs to listen and engage with those that usually have no voice - it is only through listening to those of different ages, gender, socioeconomic status, and privilege that government officials can truly understand the concept of inclusive development," said WSSCC's Chair and Minister of Environment of Nigeria Amina J. Mohammed. The Sanitation Action Summit will support and accelerate SBM objectives by bringing together citizens from across India who are often silent and/or invisible in conversations and programming-elderly men and women, transgender persons, deaf, blind people, adolescent girls and boys, and many others. According to UNICEF and the World Health Organization, "progress (at ending open defecation in the world) among the poorest has been slower, and in India there has been very little change over the past 20 years." SBM, with its renewed focus on collective behaviour change, has made considerable progress reversing this trend, promoting open defecation-free villages and States throughout India. Challenges remain, particularly on reaching marginalized populations. The Action Summit will offer practical ways to contribute directly to SBM. Notable speakers at the event will include officials from GoI, GoM, Parliament, Global Citizen, WSSCC and elsewhere. Held during a momentous week for sanitation issues in India, alongside World Toilet Day and the first Global Citizen Festival to be held in India, the Sanitation Action Summit will be a constructive dialogue to support achievement of a clean India for everyone, everywhere all of the time. "Over half a million Indian citizens have engaged in our campaigns on these issues since we launched Global Citizen India just eight weeks ago - taking over 2million social good actions. Improved access to clean water and proper sanitation is a key part of India's journey to a sustainable future - free of extreme poverty. We commend the leadership of Minister Mohammed, Dr. Chris Williams and our partners at WSSCC to reach this goal," said Hugh Evans, CEO, Global Citizen.


Kausar A.,Government Medical College | Mudassir S.,Government of Maharashtra | Badaam K.M.,Government Medical College | Shete A.N.,Government Medical College | Khan S.,Government Medical College
Journal of Clinical and Diagnostic Research | Year: 2015

Background: Volleyball is considered a physically demanding athletic sport; characterized by rapid acceleration, deceleration, and sudden changes of direction. It has been highlighted that aerobic capacity (VO2 max) which indicates cardiorespiratory fitness has a significant effect on the performance of athletes and is an important element of success in sports. Aim and Objective: The objective of this study was to compare aerobic capacity of university volleyball players from the region with that of matched sedentary controls. The secondary objective was to compare the findings with the aerobic capacity data reported in literature for the volleyball players and sedentary population. Materials and Methods: Sample size was calculated for detecting a large effect size (Cohen’s d = 0.8) with α as 0.05 and power of study as 80% for two tailed hypothesis testing. By using Queen’s college step test, VO2 max was measured in 30 male volleyball players in the age group of 20 to25 years and was compared with 30 age and socio-economic status matched controls with sedentary lifestyle. results: The mean predicted VO2 max was 52.99 ± 5.13 ml/ kg/min in volleyball players and 37.01 ± 3.94 ml/kg/min in controls. The difference in mean values of VO2 max (ml/kg/ min) in volleyball players and controls was statistically highly significant with p-value less than 0.001. conclusion: The volleyball players showed a superior aerobic capacity compared with age and socio-economic status matched controls with sedentary lifestyle. © 2015, Journal of Clinical and Diagnostic Research. All rights reserved.


Suryawanshi C.S.,Government of Maharashtra
Indian Concrete Journal | Year: 2012

"Just as walking is but a succession of interrupted falls, the entire history of human progress is a succession of stumbling half-truths and misinterpreted facts. The 'accepted facts' of today become the 'recognized fallacies' of tomorrow." - ACI Past President Herbert J. Gilkey (1950) In recent years, durability problems, poor performance, and, most of all, repair failures have tarnished the public's image of concrete. Repair failures and endless "repair of repairs" make a substantial contribution to the current perception of concrete. Concrete often gets a bad name because premature repair failure is one of the most visible manifestations of poor design decisions and details, and inadequate field practice. Concerned with the current state of concrete repair technology, the author wrote this article in an attempt to improve the performance of repaired structures. To do so, the author has analysed some common problems with structural repairs especially those in coastal regions, explored issues that must be investigated further and attempted to provide revised opinions on various concrete repair issues.


Siddamal U.V.,Government of Maharashtra | Birajdar C.A.,Government of Maharashtra
WIT Transactions on Ecology and the Environment | Year: 2012

An integrated Kukadi irrigation project in western ghat of Maharashtra state in India comprises of five dams built on the Kukadi River and its tributaries receiving seasonal rains. The water from four reservoirs namely Dimbhe, Manikdoh, Wadaj and Pimpalgaon Joge is fed to Yedgaon reservoir through canal and river. The command area of the Kukadi integrated system downstream of Yedgaon dam extends over three districts. The total irrigable command area under the entire Kukadi project is 156278 Ha. The irrigation requirement of the command area is increasing with completion of the canal system over a period of time. Thus storage in all five reservoirs is to be optimized to its full capacities by the end of monsoon following the approved reservoir operation schedule, to meet irrigation and drinking water requirements of the project for complete water year. In the Kukadi integrated project the works of five dams namely Yedgaon (1976), Wadaj (1975), Manikdoh (1986) Pimpalgaon Joge (1999) and Dimbhe (2001) are completed. The Reservoir has received a yield of more than 75% dependable yield only twice during the last 25 years since its completion. An integrated project comprising of five reservoirs is being severely affected due to less rains than estimated in the Manikdoh catchment area. Due to this fact the storage capacity of Manikdoh reservoir is underutilized and adversely affected the performance of the integrated Kukadi project, ultimately resulting in a great stress on the minds of management engineers to fulfill the targets with limited water resources. In contrast, the Dimbhe catchment is drawing increased yield than estimated and excess water spills over. The topographical suitability for linking two reservoirs is met with as Dimbhe reservoir is situated at higher elevation than Manikdoh reservoir. © 2012 WIT Press.


Doke P.P.,Government of Maharashtra
Indian journal of public health | Year: 2011

The year 2006 witnessed an extensive outbreak of Chikungunya fever in Maharashtra state. Out of 6467 sera of suspected patients sent to National Institute of Virology, Pune, 804 were serologically confirmed. This retrospective study was carried out by interrogating all those patients for their sickness experience. Adult females from rural area were more affected than males. In 68.2% families, there were multiple cases. Fever and multiple joint involvement were almost invariable. In 36.5% patients, there was history of recurrence. Along with pain, slight swelling was noticed in 55% patients. The commonest joints involved were wrist, inter-phalangeal, elbow, knee and ankle, in that order. The pain and swelling persisted for more than a month. After health education during outbreak, there was positive improvement in behavior pertaining to source reduction of vector. Inter-personal communication was best remembered. In health education, the role of paramedical workers and government doctors was prominent.


PubMed | Government of Maharashtra
Type: Journal Article | Journal: Indian journal of public health | Year: 2012

The year 2006 witnessed an extensive outbreak of Chikungunya fever in Maharashtra state. Out of 6467 sera of suspected patients sent to National Institute of Virology, Pune, 804 were serologically confirmed. This retrospective study was carried out by interrogating all those patients for their sickness experience. Adult females from rural area were more affected than males. In 68.2% families, there were multiple cases. Fever and multiple joint involvement were almost invariable. In 36.5% patients, there was history of recurrence. Along with pain, slight swelling was noticed in 55% patients. The commonest joints involved were wrist, inter-phalangeal, elbow, knee and ankle, in that order. The pain and swelling persisted for more than a month. After health education during outbreak, there was positive improvement in behavior pertaining to source reduction of vector. Inter-personal communication was best remembered. In health education, the role of paramedical workers and government doctors was prominent.

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