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Kumar A.K.S.,UNICEF India | Chen L.C.,Harvard Global Equity Initiative | Choudhury M.,National Institute of Public Finance and Policy | Ganju S.,Consultant Ingalls Hospital | And 3 more authors.
The Lancet | Year: 2011

India's health financing system is a cause of and an exacerbating factor in the challenges of health inequity, inadequate availability and reach, unequal access, and poor-quality and costly health-care services. Low per person spending on health and insufficient public expenditure result in one of the highest proportions of private out-of-pocket expenses in the world. Citizens receive low value for money in the public and the private sectors. Financial protection against medical expenditures is far from universal with only 10% of the population having medical insurance. The Government of India has made a commitment to increase public spending on health from less than 1% to 3% of the gross domestic product during the next few years. Increased public funding combined with flexibility of financial transfers from centre to state can greatly improve the performance of state-operated public systems. Enhanced public spending can be used to introduce universal medical insurance that can help to substantially reduce the burden of private out-of-pocket expenditures on health. Increased public spending can also contribute to quality assurance in the public and private sectors through effective regulation and oversight. In addition to an increase in public expenditures on health, the Government of India will, however, need to introduce specific methods to contain costs, improve the efficiency of spending, increase accountability, and monitor the effect of expenditures on health. © 2011 Elsevier Ltd. Source

Sharma C.,All India Institute of Medical Sciences | Dey B.,Government of India | Wahiduzzaman M.,All India Institute of Medical Sciences | Singh N.,All India Institute of Medical Sciences
Vaccine | Year: 2012

Cervical cancer is found to be associated with human papillomavirus (HPV) infection, with HPV16 being the most prevalent. An effective vaccine against HPV can thus, be instrumental in controlling cervical cancer. An ideal HPV vaccine should aim to generate both humoral immune response to prevent new infection as well as cell-mediated immunity to eliminate established infection. In this study, we have generated a potential preventive and therapeutic candidate vaccine against HPV16. We expressed and purified recombinant HPV16 L1ΔN26-E7ΔC38 protein in E. coli which was assembled into chimeric virus like particles (CVLPs) in vitro. These CVLPs were able to induce neutralizing antibodies and trigger cell-mediated immune response, in murine model of cervical cancer, exhibiting antitumor efficacy. Hence, this study has aimed to provide a vaccine candidate possessing both, prophylactic and therapeutic efficacy against HPV16 associated cervical cancer. © 2012 Elsevier Ltd. Source

Khan P.K.,Indian School of Mines | Mohanty S.,Indian School of Mines | Mohanty M.,Government of India
Surveys in Geophysics | Year: 2010

We propose here that the 8 October 2005 North Pakistan earthquake occurred beneath the wedge-top of Balakot Formation in the Hazara-Kashmir syntaxial area. Slip occurred along the Muzaffarabad thrust, a southeast extended part of the Indus-Kohistan seismic zone. Tectonic loading of the high-density wedge/thrust sheet between the wedge-top and the descending Indian lithosphere coupled with continued flexural tectonics provoked this earthquake. The obliquely converging Indian plate along with block rotations led to development of a pinned zone around Northwestern Syntaxis of the Himalayas. Strain adjustment related to the rotational deformation processes resulted in the buckling of the more competent rock-units sandwiched between the less competent rock-units around the Hazara-Kashmir syntaxis. The western limb of the buckled unit gave rise to the development of thrusts and associated oblique slip in the inner arc of the competent rock-unit. The observations demonstrate reactivated tectonic movement along the growing fracture-tip of the buried Riasi thrust. © Springer Science+Business Media B.V. 2009. Source

A method of producing a composite plasma spray coating using simultaneous feeding of powder and solution precursor feedstock in a plasma spray gun is disclosed, comprising the steps of a) spraying a powder feedstock comprising micron sized particles into a plasma spray plume; and b) spraying a liquid feedstock comprising liquid precursor solution into the plasma spray plume, wherein the spraying of the powder feedstock and spraying of the liquid feedstock are independently controllable. The method allows control of coating composition and microstructure to deposit nanostructured and microstructured layers either sequentially to form layered coatings, or simultaneously to form either composite coatings or continuously gradient coatings to address diverse applications. Thermal barrier coatings produced using the new method have demonstrated twice the life compared to conventional air plasma sprayed coatings.

The Global Wind Energy Council’s annual review of the wind sector in 2015 provides further evidence of the accelerating momentum in the world’s shift to a lower-emissions global economy. GWEC reports annual installation growth of 22 percent year over year to a record 63.5 gigawatts. Cumulative global installs reached 432.9 gigawatts. This builds on record solar installations globally in 2015 and significant progress in tenergy efficiency. The combined impacts included a decline in the global consumption of thermal coal in 2015. IEEFA expects these trends to accelerate in 2016 and beyond as technology developments continue to improve the relative cost competitiveness of low-emissions technologies and the policy headwinds to fossil fuels builds on the international climate-change agreement inked last year in Paris. Geographically, the wind industry’s growth is skewed heavily toward the Asia-Pacific region. China installed a world record 30-32 gigawatts of wind in 2015 (the official tally varies by source and definition of when a project is formally commissioned). India was the fifth largest installer of wind globally, with installs of 2.6 gigawatts to take its total cumulative installs to 25 gigawatts. We note that the Government of India has set a target of 60 gigawatts of cumulative wind installs by 2021-22, suggesting that policy developments will more than double installs before the end of this decade.

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