Nscb Government Medical College

Jabalpur, India

Nscb Government Medical College

Jabalpur, India

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Agarwal P.,Nscb Government Medical College | Singh M.,Nscb Government Medical College | Sharma D.,Nscb Government Medical College
Indian Journal of Surgery | Year: 2015

There is little information available on the bacteriological contamination of Cheattle’s forceps during routine use and the effects of antiseptic solutions. This study was conducted to detect infection in various antiseptics and disinfections in-use used for keeping the Cheattle’s forceps in surgical wards. An aqueous solution of 0.5 and 1 % cetrimide/chlorhexidine, 2.4 % glutaraldehyde, 5 % povidone iodine, and 10 % chloroxylenol were compared using the normal saline as control. The samples from each bottle were sent for culture on the 3rd, 5th, and 7th day. All the culture reports were analyzed and statistically compared. A total of 2,160 samples were sent for culture from solutions including control over a period of 7 days. A total of 360 samples were sent for culture from each antiseptic solution. Out of 2,160 samples, 240 (11.11 %) were positive over a period of 7 days for contamination with microbial organisms. The most common organism isolated was Pseudomonas present in 140 samples followed by E. coli in 71 samples. S. aureus was present in seven samples, bacillus in ten samples, and Coaglase -ve Streptococcus and Klebsiella in six samples each. Number of positive culture consistently increased in normal saline and cetrimide/chlorhexidine, but povidone iodine, chloroxylenol, and glutaraldehyde did not show any positive culture on the 3rd day. Povidone iodine and glutaraldehyde showed positive culture on the 5th and 7th day, respectively., but they were statistically insignificant. On the 7th day, glutaraldehyde was the only solution which did not show any positive culture. We strongly recommend that the Cheattle’s forceps should be kept in a bottle containing glutaraldehyde or chloroxylenol. © 2014, Association of Surgeons of India.


Agrawal V.,NSCB Government Medical College
Asian journal of endoscopic surgery | Year: 2012

Purulent pericarditis is an extremely rare complication of pneumococcal pneumonia in children that may result in to cardiac tamponade. While image-guided pericardiocentesis is the treatment of choice for such a condition, it may fail in the presence of thick pus; loculations and thoracoscopic pericardiotomy are useful procedures for such situations. Herein, we report such a case involving a 6-year-old boy who presented with purulent pneumococcal pericarditis that was managed with thoracoscopic pericardiotomy and who recovered well. Thoracoscopic pericardiotomy is a safe procedure that allows effective drainage under vision, pericardial biopsy for diagnosis, and a simultaneous opportunity to perform thoracoscopic pleural drainage. © 2012 Japan Society for Endoscopic Surgery, Asia Endosurgery Task Force and Blackwell Publishing Asia Pty Ltd.


Dubey A.K.,Sharda University | Raichandani O.M.,Nscb Government Medical College | Pandey S.P.,Nscb Government Medical College
International Journal of Pharma and Bio Sciences | Year: 2012

Background: Major Depressive Disorder (MDD) is a chronic illness with large contribution to disease burden worldwide.Duloxetine, a dual reuptake inhibitor of 5-HT and NE, is a second generation antidepressant, on which, to the best of our knowledge, there is no study in the Indian adult patients of MDD. There have been studies on duloxetine in MDD patients inother parts of the world, but there has not yet been a study comparing it with the old standard imipramine, a tricyclic acid antidepressant, still commonly used in the primary health care set up. Aims: In this study the efficacy of duloxetineinMDD was compared with that of imipramine. Settings and Design: Prospective observer blinded parallel group comparative study. Materials and Methods: Consenting adult patients (N=60) meeting DSM-IV criteria for MDD who completed six weeks of treatment with, either duloxetine (40 mg) or imipramine (150 mg), were compared for improvement with their base line disease severity, measured by scores on the Hamilton Depression (HAM-D) Rating Scale with 21 items and Clinical Global Impression (CGI) scale. The primary efficacy measure was mean change from baseline to endpoint on the HAM-D scale. Results: The totalchange in HAM-D score in imipramine group was -25.53 (±7.82) exhibiting an improvement of 67.54% and the total change in HAM-D score in duloxetine group was -20.27(±7.04) showing an improvement of 60.45%. Imipramine showed a slightly greater reduction of HAM-D scores as compared to duloxetine, which was statistically significant, but there was no statisticallysignificant difference between the response rates (80% vs 73.3%) and remission rates (30% vs 26.7%) for imipramine and duloxetine, respectively, at six weeks. Conclusion: The efficacy of duloxetine and imipramine is comparable in MDD with no significant difference in response and remission rates at six weeks.


Badkur P.,NSCB Government Medical College | Singh K.N.,NSCB Government Medical College | Singh K.N.,Tata Memorial Hospital Mumbai | Singh K.N.,State University of New York at Buffalo | And 2 more authors.
Journal of Obstetrics and Gynecology of India | Year: 2016

Aims and Objectives: To study the colposcopic findings and prevalence of lower genital tract infections in HIV-positive women on anti-retroviral therapy. To find correlation between colposcopic finding, m RNA HPV and cytology of lower genital tract infections in HIV-positive women on anti-retroviral therapy. Materials and Methods: The present prospective observational study was conducted in the Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur, from 1 June 2013 to 31 October 2014. The data of the present study was recorded into computer and after proper validation, error checking, coding and decoding, the data was compiled and analysed using the SPSS Windows. Appropriate univariate and bivariate analysis were carried out using the Student’s t test and two-tailed Fisher exact test or Chi-square test for categorical variables. Results and Conclusion: The present study concludes that the prevalence of lower genital tract infections is 25.3 % in HIV-positive women on anti-retroviral therapy. It revealed that 35 HIV-positive women on anti-retroviral therapy who were screened for m HPV RNA test, one came out to be positive (i.e. 2.8 %); thus, it can be said that there is an increased clearance of oncogenic HPV types in HIV-positive women on anti-retroviral therapy. © 2016 Federation of Obstetric & Gynecological Societies of India


PubMed | Nscb Government Medical College
Type: Journal Article | Journal: Indian journal of clinical biochemistry : IJCB | Year: 2012

Changes in erythrocyte membrane glycoproteins during, leukaemia were investigated in one hundred patients. Control group contained normal ones. The total protein and protein bound total carbohydrates (neutral sugars) in the glycoproteins extracted from the erythrocyte membrane showed significant reduction in total protein and protein bound total carbohydrates before radiotherapy. However, after the radiotherapy there was further reduction in total protein by 10.41% whereas there was increase in total carbohydrates by 9.98%. Qualitative analysis reveals that with the help of lectins one can pin point the sugars which appear or disappear due to leukaemia. The test could be of a diagnostic value.


PubMed | NSCB Government Medical College and Tata Memorial Hospital Mumbai
Type: Journal Article | Journal: Journal of obstetrics and gynaecology of India | Year: 2016

To study the colposcopic findings and prevalence of lower genital tract infections in HIV-positive women on anti-retroviral therapy. To find correlation between colposcopic finding, m RNA HPV and cytology of lower genital tract infections in HIV-positive women on anti-retroviral therapy.The present prospective observational study was conducted in the Department of Obstetrics and Gynaecology, Netaji Subhash Chandra Bose Medical College, Jabalpur, from 1 June 2013 to 31 October 2014. The data of the present study was recorded into computer and after proper validation, error checking, coding and decoding, the data was compiled and analysed using the SPSS Windows. Appropriate univariate and bivariate analysis were carried out using the Students t test and two-tailed Fisher exact test or Chi-square test for categorical variables.The present study concludes that the prevalence of lower genital tract infections is 25.3% in HIV-positive women on anti-retroviral therapy. It revealed that 35 HIV-positive women on anti-retroviral therapy who were screened for m HPV RNA test, one came out to be positive (i.e. 2.8%); thus, it can be said that there is an increased clearance of oncogenic HPV types in HIV-positive women on anti-retroviral therapy.


PubMed | NSCB Government Medical College
Type: Clinical Trial | Journal: Journal of pediatric urology | Year: 2013

To assess the feasibility of laparoscopy in the treatment of pediatric urolithiasis, we report our experience with the transperitoneal laparoscopic removal of stones.Renal pelvic stones of size 1 cm on ultrasound were included for laparoscopic pyelolithotomy while smaller stones were managed with shock-wave lithotripsy monotherapy. Intrarenal stones, calyceal stones, complete staghorn stones, multiple stones and kidneys with intrarenal pelvis were excluded. Ureteric stones included for laparoscopic ureterolithotomy were of size 1 cm in the upper, mid or lower ureter, and smaller stones not responding to non-operative treatment.A total of 22 procedures were performed: 12 pyelolithotomies, and 8 lower and 2 upper ureterolithotomies. Complete removal of calculi was accomplished in 21 (95.45%) procedures. Complications associated with laparoscopic lithotomy included urinoma (4.54%), failure (4.54%) and omental prolapse (4.54%).Laparoscopic lithotomy is safe and feasible in pediatric urolithiasis with pyelic and ureteric stones, with minimal complications and failure rate.


PubMed | NSCB Government Medical College
Type: Case Reports | Journal: Asian journal of endoscopic surgery | Year: 2012

Purulent pericarditis is an extremely rare complication of pneumococcal pneumonia in children that may result in to cardiac tamponade. While image-guided pericardiocentesis is the treatment of choice for such a condition, it may fail in the presence of thick pus; loculations and thoracoscopic pericardiotomy are useful procedures for such situations. Herein, we report such a case involving a 6-year-old boy who presented with purulent pneumococcal pericarditis that was managed with thoracoscopic pericardiotomy and who recovered well. Thoracoscopic pericardiotomy is a safe procedure that allows effective drainage under vision, pericardial biopsy for diagnosis, and a simultaneous opportunity to perform thoracoscopic pleural drainage.


PubMed | NSCB Government Medical College
Type: Journal Article | Journal: Asian journal of neurosurgery | Year: 2016

Steep learning curve is found initially in pure endoscopic procedures. Video telescopic operating monitor (VITOM) is an advance in rigid-lens telescope systems provides an alternative method for learning basics of neuroendoscopy with the help of the familiar principle of microneurosurgery.The aim was to evaluate the clinical utility of VITOM as a learning tool for neuroendoscopy.Video telescopic operating monitor was used 39 cranial and spinal procedures and its utility as a tool for minimally invasive neurosurgery and neuroendoscopy for initial learning curve was studied.Video telescopic operating monitor was used in 25 cranial and 14 spinal procedures. Image quality is comparable to endoscope and microscope. Surgeons comfort improved with VITOM. Frequent repositioning of scope holder and lack of stereopsis is initial limiting factor was compensated for with repeated procedures.Video telescopic operating monitor is found useful to reduce initial learning curve of neuroendoscopy.

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