Government College University at Faisalabad

gcuf.edu.pk/
Faisalabad, Pakistan

Government College University Faisalabad is a general university in the industrial and agricultural hub of Pakistan, Faisalabad. According to the latest university rankings by HEC, GCUF is on 5th position in general universities ranking list.The GC University’s journey started as a primary school in 1897 in the present building of Govt. College for Women, Karkhana Bazar, Faisalabad. It was promoted to High School and Intermediate College in 1905 and 1924 respectively. It was elevated to the degree level in 1933 and postgraduate disciplines were introduced in 1963. The long journey that started with the humble beginning reached its climax when it was granted the status of University in October 2002.The GC University, Faisalabad has a long history of excellence and distinction as an institution. Renowned scholars and eminent personalities have served this institution in various capacities at various stages of its history. It has produced outstanding personnel who have earned great fame not only for themselves but also for the nation.There are at least 43 nobel laureate associated with GC University is varying capacities. The famous physicist Ernest Rutherford worked here in early twentieth century and suggested the Rutherford Model of atomic structure while working in GC University which was then an Intermediate college.The luminaries like Mr. Abdul Hameed, Mr. W.H.F. Armstrong, Mr. Lala Chattan Annand, Mr. Hashmat Khan, Mr. Taj Khyal, Mr. Namdar Khan, Mr. Karamat Hussain Jafari, Mr. Mukhtar Mahmood Qureshi, Dr. Asif Iqbal Khan and Dr. Arif Zaidi have served this institution.The government of the Punjab declared Government College, Faisalabad an autonomous institution in 1990. The college was given the status of university on 23 October 2002.There are more than 35 faculties in GCUF including Electrical Engineering and Pharmacy.Electrical engineering department is affiliated with Pakistan Engineering Council .Pharmacy is affiliated with Pakistan Pharmacy Council Wikipedia.

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Patent
COMSATS Institute of Information Technology and Government College University at Faisalabad | Date: 2016-08-22

A method of synthesizing a resin including mixing a first solution including a melamine compound with a second solution including glutaraldehyde to form a third solution, heating the third solution to 35 C. to 90 C. in at a pH above 7 for 5 to 70 minutes, and cooling the third solution to room temperature.


Khan M.K.,Government College University at Faisalabad | Zill-E-Huma,National University of Sciences and Technology | Dangles O.,University of Avignon
Journal of Food Composition and Analysis | Year: 2014

The consumption of Citrus fruits and juices has been widely investigated for its possible role in the prevention of cardiovascular disease and cancer. These beneficial effects are mainly attributed to flavanones, the typical polyphenols of Citrus species. Major flavanones in plant species include hesperetin, naringenin, eriodictyol, isosakuranetin and their respective glycosides. Hesperetin and its derivatives are characteristic flavanones of sweet orange, tangelo, lemon and lime, while naringenin and its derivatives are those of grapefruit and sour orange. Advances in analytical techniques like ultra high performance liquid chromatography (UPLC) coupled with mass spectrometry has facilitated (a) the estimation of flavanone contents in other plant species and in humans after ingestion and (b) the determination of flavanone metabolites more rapidly and with greater efficiency. The present review will summarize the current knowledge about flavanones from their occurrence in plants to the bioactivity of their metabolites in humans. © 2013 Elsevier Inc.


Abbas F.,Government College University at Faisalabad
Earth Interactions | Year: 2013

Prolonged droughts and uneven monsoons have adversely affected socioeconomic and environmental conditions of Pakistan, especially of the Punjab province. Analysis of historical (1981-2010) daily minimum and maximum temperatures from five cities in semiarid Punjab, Pakistan, was carried out to evaluate spatial and temporal patterns in thermal regimes. A total of 13 climate change indices were calculated using daily minimum and maximum temperatures and analyzed for trend using RClimDex, a program written in the statistical software package R. A nonparametric Mann-Kendall test and Sen's slope estimates were used to determine the statistical significance and magnitude of a trend, respectively. Observed trends in selected indices during 1981-2010 suggest an overall warming in the region. Over the analysis period, the regionally averaged occurrence of extreme cold (10th percentile) nights and days has decreased by 23.94 nights per decade and 20.61 days per decade, respectively. Occurrence of extreme hot (90th percentile) nights and days has increased by 4.19 nights per decade and 0.92 days per decade, respectively. The number of summer days has increased by almost 3 days per decade on average at four out of the five cities. Multan was the only city where the number of summer days has declined by 5 days per decade. Regionally averaged increase in tropical nights was 8.35 nights per decade. Regional warming will dictate increased crop water requirements in this semiarid region agriculture, which is already under water-scarce conditions, especially in the Faisalabad district, where saline groundwater is not suitable for crops. © 2013.


Ashfaq U.A.,Government College University at Faisalabad | Idrees S.,Government College University at Faisalabad
World Journal of Gastroenterology | Year: 2014

Hepatitis C virus (HCV) is a global health concern which is responsible for most of the liver diseases. Currently, there is no vaccine available for prevention of HCV infection due to the high degree of strain variation. The current standard of care is a combination of pegylated interferon α with ribavirin and boceprevir/telaprevir. This treatment was partially effective and had significant side effects. Hence, there is a need to develop new antiviral agents that interfere with different stages of the HCV life cycle. Recent advances in the understanding of both the cellular and molecular mechanisms of HCV replication have provided the basis for novel therapeutic strategies. Several hundred plant species and their phyto-constituents have been isolated for screening against HCV, and some have been shown to have great medicinal value in preventing and/or ameliorating viral diseases in pre-clinical and clinical trials. This review summarizes medicinal plants and their phytochemicals which inhibit different stages of HCV life cycle and discuss their potential use in HCV therapy. © 2014 Baishideng Publishing Group Co., Limited. All rights reserved.


Anjum F.,Government College University at Faisalabad | Shahid M.,University of Agriculture at Faisalabad | Akcil A.,Suleyman Demirel University of Turkey
Hydrometallurgy | Year: 2012

The demand for metals is ever increasing with the advancement of the industrialized world. On the other hand, worldwide reserves of high grade ores are close to depletion. However, there exists a large reserve of metals in low and lean grade ores and other secondary sources. Metal recovery from low and lean grade ores using conventional techniques such as pyrometallurgy, etc. requires high energy and capital inputs which often result in the secondary environmental pollution. Thus, there is a need to utilize more efficient technologies to recover metals. Biohydrometallurgy, which exploits microbiological processes to recover metal ions, is regarded as one of the most promising and revolutionary biotechnologies. The products of such processes are dissolved in aqueous solution, thereby rendering them more amenable to containment, treatment and recovery. On top of this, biohydrometallurgy can be conducted under mild conditions, usually without the use of any toxic chemicals. Consequently, the application of biohydrometallurgy in the recovery of metals from lean grade ores and wastes has made it an eco-friendly technology for enhanced metal production. This paper reviews the current status of biohydrometallurgy of low grade ores around the world. Particular attention is focused on the bioleaching of black shale ore and its metallogenic diversity in the world. The review assesses the status of bioprocesssing of metals to evaluate promising developments. Bioleaching of metals is comprehensively reviewed with the emphasis on the contribution of microbial community, especially fungal bioleaching coupled with ultrasound treatment. In this manuscript, the principles of bioleaching, their mechanisms, and commercial applications are presented. The case studies and future technology directions are also reviewed. © 2012 Elsevier B.V.


Nasreen S.,Government College University at Faisalabad | Anwar S.,Government College University at Faisalabad
Energy Policy | Year: 2014

This paper explores the causal relationship between economic growth, trade openness and energy consumption using data of 15 Asian countries. The study covers the period of 1980-2011. We have applied panel cointegration and causality approaches to examine the long-run and causal relationship between variables.Empirical results confirm the presence of cointegration between variables. The impact of economic growth and trade openness on energy consumption is found to be positive. The panel Granger causality analysis reveals the bidirectional causality between economic growth and energy consumption, trade openness and energy consumption. © 2014 Elsevier Ltd.


The genome sequence analysis of Bacillus thuringiensis serovar konkukian S4 has shown to contain two chitinases (Chi74, Chi39) and two chitin-binding proteins (CBP50 and CBP24). The Chi74, Chi39 and CBP50 have been characterized previously. The chitin-binding protein CBP24 was cloned and heterologously expressed in Escherichia coli. The recombinant protein was purified using a Ni-NTA purification system. The purified protein was used to study its substrate binding activity using crystalline chitin variants as substrates. The Bmax and Kd values have shown that it preferably binds to β-type of the crystalline chitin at a range of pH with peak activity between 5.5-7.5. To elucidate the role of CBP24 in the chitin degradation system of S4, the purified chitinases Chi74, Chi39 along with the ChiA from Serratia proteamcualans were used in different combinations with the CBP24 and chitinolytic activity was assayed. It was shown that the CBP24 acts synergistically with chitin degradation activity of bacterial chitinases non-specifically. Moreover, the CBP24 has shown antifungal activity against plant pathogenic fungi Fusarium oxysporum and Rhizoctonia solani. The present study will lead us to develop a technology for environmental friendly conversion of chitin to valuable products.


Iqbal S.Z.,Government College University at Faisalabad | Asi M.R.,Nuclear Institute for Agriculture and Biology
Food Control | Year: 2013

The basic objective of this research was to investigate the incidence and occurrence of aflatoxin M 1 (AFM 1) in milk and dairy products produced in the province of Punjab, Pakistan. Milk samples (107) and dairy products including yogurt (96), white cheese (119), cheese cream (150) and butter (74) samples were analyzed using High performance liquid chromatography equipped with fluorescence detector. The results have shown that AFM 1 was detected in 71% of milk samples with 58% samples were found above the permissible limit of European Union (EU). AFM 1 was detected in 61% of yogurt, 78% white cheese, 59% cheese cream and 45% butter samples with 47, 15, 11 and 52% samples of yogurt, white cheese, cheese cream and butter, respectively were found above the recommended limit of EU. The data of the present study will be helpful for the implementation of regulatory limit for AFB 1 in order to minimize or avoid AFM 1 in milk and milk products from Pakistan and also gives insights that whether the occurrence of AFM 1 in dairy products was considered as a possible risk for consumers health. © 2012 Elsevier Ltd.


Akash M.S.H.,Zhejiang University | Akash M.S.H.,Government College University at Faisalabad | Rehman K.,Zhejiang University | Chen S.,Zhejiang University
Journal of Cellular Biochemistry | Year: 2013

Type 2 diabetes mellitus (T2DM) is characterized by progressive β-cell dysfunctioning and insulin resistance. This article reviews recent literature with special focus on inflammatory mechanisms that provoke the pathogenesis of T2DM. We have focused on the recent advances in progression of T2DM including various inflammatory mechanisms that might induce inflammation, insulin resistance, decrease insulin secretion from pancreatic islets and dysfunctioning of β-cells. Here we have also summarized the role of various pro-inflammatory mediators involved in inflammatory mechanisms, which may further alter the normal structure of β-cells by inducing pancreatic islet's apoptosis. In conclusion, it is suggested that the role of inflammation in pathogenesis of T2DM is crucial and cannot be neglected. Moreover, the insight of inflammatory responses in T2DM may provide a new gateway for the better treatment of diabetes mellitus. J. Cell. Biochem. 114: 525-531, 2013. © 2012 Wiley Periodicals, Inc.


Akash M.S.H.,Government College University at Faisalabad | Rehman K.,University of Agriculture at Faisalabad
Journal of Controlled Release | Year: 2015

Abstract Most of the administered anti-cancer drugs are hydrophobic in nature and are known to have poor water solubility, short residence time, rapid clearance from the body and systemic side effects. Polymeric-based targeted particulate carrier system has shown to directly deliver the encapsulated anti-cancer drug to the desired site of action and prevent the interaction of encapsulated drug with the normal cells. Pluronic F127 (PF127) has been widely investigated for its broad-range of therodiagnostic applications in biomedical and pharmaceutical sciences, but rapid dissolution in the physiological fluids, short residence time, rapid clearance, and weak mechanical strength are the main shortcomings that are associated with PF127 and have recently been overcome by making various modifications in the structure of PF127 notably through preparation of PF127-based mixed polymeric micelles, PF127-conjugated nanoparticles and PF127-based hydrophobically modified thermogels. In this article, we have briefly discussed the recent studies that have been conducted on various anti-cancer drugs using PF127 as nano-carrier modified with other copolymers and/or conjugated with magnetic nanoparticles. The key findings of these studies demonstrated that the modified form of PF127 can significantly increase the stability of incorporated hydrophobic drugs with enhanced in vitro cytotoxicity and cellular uptake of anti-cancer drugs. Moreover, the modified form of PF127 has also shown its therapeutic potentials as therodiagnostics in various types of tumors and cancers. Hence, it can be concluded that the modified form of PF127 exhibits significant therodiagnostic effects with increased tumor-specific delivery of anti-cancer drugs having minimal toxic effects as compared to PF127 alone and/or other copolymers. © 2015 Elsevier B.V. All rights reserved.

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