Neela R.,Manonmaniam Sundaranar University |
Kalaimagal R.,Government Arts College for Men Autonomous
International Journal of Applied Engineering Research | Year: 2015
Image segmentation plays most important role in computer vision. Segmentation of medical image is the first step in the diagnosis and treatment of various diseases. Segmenting brain MRI data is the most crucial step in medical image analysis. Template based segmentation gives good results when compared to other segmentation techniques. Using multiple atlases as templates, these methods, has two phases, registration and fusion. Registration is finding geometric relationship between two images, which yields segmentation for each atlas. After registration, label fusion step is required to fuse all segmentations into a single final segmentation. In this paper we propose a new label fusion strategy for segmenting sub cortical brain structures from T1 weighted MRI scans using priori knowledge and maximum multi graph cut. We test our framework for segmenting subcortical brain structures on the SATA(MICCAI 2012) challenge data set. We evaluate our algorithm using dice overlap and Jaccard similarity index. © Research India Publications.
Martin P.,P.A. College |
Selvin Samuel A.,St Johns College |
Manthrikumar Rajesh A.,Government Arts College for Men Autonomous |
Indian Journal of Environmental Protection | Year: 2012
Water samples were taken at 11 sampling stations along the stretch of the perennial river Tamiraparani. Enumeration of total coliforms (TC) and faecal coliforms (FC) were undertaken using the MPN (most probable number) technique. The total plate count (TPC) was enumerated seasonally in water and sediments. The highest TC count was detected in station 9 (15,000/100 mL) and FC count in station 7 (9,300/100 mL) where small and large sewage drains entered the river. The lowest density of TC was observed at station 2, 3, 5 and 11 (30/100 mL) and that of FC at station 2 (4/100 mL). This was mainly due to impact of textile mill effluent influence in station 2 and 3 and the devoid of open defecation in station 5 and 11. The TPC (total plate count) of sediments was always higher than that of water. Water from all stations were unsuitable for direct consumption, as shown by TC and FC concentration. Water collected by the people directly from basin should, therefore, be boiled and then cooled before being used for drinking or food preparation. Such an approach should significantly reduce the incidence of water-borne diseases. © 2012 - Kalpana Corporation.
Martin P.,Government Arts College for Men Autonomous |
Jesvin Bency B.,Government Arts College for Men Autonomous |
Jesvin Bency B.,St Johns College |
Kuppan A.,Government Arts College for Men Autonomous |
And 2 more authors.
Indian Journal of Environmental Protection | Year: 2013
Water samples were collected from Thamiraparani and Palayaru river basin in Kanyakumari district, Tamil Nadu during the period from April to June 2007, for microbial, analysis. River water samples collected from 6 sampling stations showed higher total viable count (TVC) and total microbial count (TMC). Among the river water (RW) samples, maximum load of coliforms and Escherichia coli was observed in RW 6 collected from Manakkudi. Pseudomonas aeruginosa was found to be maximum in the river sample RW4 (16.33 ± 7.31). Vibrio parahaemolyticus was not detected in the samples collected from Keeriparai (RW1), Thirupparapu (RW2) and Paechippara (RW3). In general the river water samples from Kuzhithurai, Olugunacheri and Manakkudi contained sulphite reducing anaerobes. Staphylococcus sp. Salmonella sp, Shigella sp.. Vibrio cholerae. Vibrio parahaemolyticus in most of the sampling days. The average number of coliforms was the highest (37.13) in the river water. Salmonella sp. was also recorded in the river water. © 2013 - Kalpana Corporation.
Pasupathi G.,AVVM Sri Pushpam College |
Murugadoss K.,AVVM Sri Pushpam College |
Senthilkumar M.,Government Arts College for Men Autonomous |
Ramachandraraja C.,Government Arts College for Men Autonomous
Optik | Year: 2014
Single crystals of novel semiorganic material, potassium diboro-oxalate (PDO) have been grown from aqueous solution by slow evaporation technique. The lattice parameters for the grown crystals were determined by the single crystal X-ray diffraction analysis and the crystallinity of the grown crystal was confirmed by powder X-ray diffraction analysis. The presence of functional groups was estimated qualitatively by using Fourier transform infrared (FTIR) analysis. The optical absorption spectrum shows that the UV cut-off wavelength for the grown crystal is at 240 nm and the band gap was calculated. The thermal stability of the grown crystal was studied by using TG/DTA analysis. The second harmonic generation and the phase-matchable tests were performed by Kurtz powder technique. The crystal perfection was analyzed by SEM photographs. © 2014 Elsevier GmbH. All rights reserved.
Thirunavukkarasu N.,Ramakrishna Mission Vivekananda College |
Suryanarayanan T.S.,Vivekananda Institute of Tropical Mycology VINSTROM |
Girivasan K.P.,Government Arts College for Men Autonomous |
Venkatachalam A.,Vivekananda Institute of Tropical Mycology VINSTROM |
And 3 more authors.
Fungal Diversity | Year: 2012
Ten marine sponge species from Rameswaram, southern India were studied for their filamentous fungal symbionts. The results suggest that fungal symbionts of marine sponges are hyperdiverse. Genera such as Acremonium, Alternaria, Aspergillus, Cladosporium, Fusarium and Penicillium were frequently isolated; no true marine fungal species were present. Species of Aspergillus were dominant and co-dominant in all the sponges screened. The fungal isolates produced antialgal, antifungal, antioxidant, antibiotic, antiinsect metabolites. A few fungi produced acetylcholinesterase inhibitors. © Kevin D. Hyde 2011.
Dinesh Raja M.,Loyola College |
Arulmozhi S.,Loyola College |
Madhavan J.,Loyola College |
Senthil S.,Government Arts College for Men Autonomous
International Journal of ChemTech Research | Year: 2014
In this work, the experimental and theoretical spectra of L -Prolinium Tartrate (LPT) were studied. The Fourier transform infrared of LPT was recorded in the solid phase. The optimized geometry was calculated by B3LYP method with 6-31+G (d,p) basis set. A detailed interpretation of the infrared spectrum of LPT was reported. The results were compared with the experimental values. The first hyperpolarizability values have been computed using DFTquantum mechanical calculation. The calculated results (β0) show that the title molecule might have nonlinear optical (NLO) behavior. The HOMO-LUMO energies were also calculated.
Kavitha E.,Dr. M.G.R. Educational and Research Institute |
Selvakumar S.,Government Arts College for men Autonomous |
Madhavan J.,Loyola College
International Journal of ChemTech Research | Year: 2014
4- methoxybenzaldehydeThiosemicarbazoneZinc Chloride (MBTZC), anmetal-organic nonlinear optical material was synthesized and the crystals were grown by slow evaporation solution growth technique for the first time. Powder X-ray diffraction study was revealed that the grown crystal belongs to monoclinic system. The Fourier transform infrared analysis was used to identify the various functional groups present in the title compound. The UV-visible absorption spectrum of MBTZCwas recorded to study the optical transmittance. Thermal stability of the sample was checked by thermogravimetric studies. The grown crystals are found to suitable for device fabrication in frequency conversion applications.
Rajesh V.,Government Arts College for Men Autonomous |
Sarthaki R.,Government Arts College for Men Autonomous |
Palani R.,Government Arts College for Men Autonomous |
Jayaraman P.,Government Arts College for Men Autonomous
International Journal of Pharmacognosy and Phytochemical Research | Year: 2014
It is reported that the naturally obtained plant foods and drugs are able to control blood glucose level which is not having any side effects. In vitro and in vivo studies on anti-diabetic activity of many plant compounds have been tested and proved efficiently to decrease the glucose level in blood. Therefore, the present study is carried out for assessing the anti-diabetic efficacy and evaluates the anti-hyperglycemic potential of the plant species Memecylon umbellatum Burm.f collected from Malachery forest, Gingee, Villupuram District, Tamil Nadu. For the analysis of anti-diabetic activity, inhibitory assay of α-amylase, non enzymatic glycosylation of hemoglobin, the Glucose diffusion assay and the glucose uptake by the yeast cells were performed. Among the solvents like methanol, ethyl acetate and hexane used for extraction from plant leaves of Memecylon umbellatum Burm.f, the methanol extract showed higher activity for anti-diabetic assay and the presence of other phyto-chemical constituents. The results for the antidiabetic assays, α-amylase inhibitory assay exhibited significant inhibitory activity as 57% – 78%, Non enzymatic glycosylation of hemoglobin shows comparable inhibitory activity with the standard drug as 47% to 62% and the percentage increase in the glucose uptake by yeast cells was found to the range between 54% to 71% in 5 mM glucose at methanol extract sample concentration of 250 - 1000 μg/ml. The Glucose diffusion assay performed and found significant level of inhibition of glucose movement at various time intervals when compared to control. The photochemical analysis of plant extract revealed the presence of phenols (1189 μg/ml), flavonoids (388 μg/ml), terpenoids, tannins, saponins and proteins; the absence of alkaloids, glycosides and reducing sugars in the methanol extract. To elucidate the bioactive compounds present in the best screened extract, they were isolated identified by chromatography in methanol:chloroform (1:9) v/v, which shows better separation of compounds and it is most distinct and clear in iodine vapour and UV light. This study presents a review on the in vitro anti-diabetic effect of Memecylon umbellatum Burm.f which provides promising results for the utilization of this plant as a formulation for the drug to treat diabetes after testing for clinical trials and further analysis. © 2014, International Journal of Pharmacognosy and Phytochemical Research. All rights reserved.
Selvaraj S.,Government Siddha Medical College |
Selvaraj S.,Tamil University |
Chittibabu C.V.,Government Arts College for Men Autonomous |
Janarthanam B.,Poonga Biotech Research Center
Asian Journal of Pharmaceutical and Clinical Research | Year: 2014
Objective: The objective of the present study was to evaluate the phytochemical constituents, total phenol, total terpenoid, anti-oxidant activity and high-performance liquid chromatography (HPLC) analysis of swertiamarin compound from the leaf extract of Enicostemma littorale.Methods: Preliminary screening involved the qualitative methods to detect the presence of terpenoids, flavonoids, phenols, tannins, steroids, quinones, saponins, cardiac glycosides and alkaloids. Total phenol and terpenoid contents were quantitatively estimated. Total phenolic content was estimated by Folin–Ciocalteau method. In vitro antioxidant activity of petroleum ether, chloroform, acetone, aqueous and ethanol extracts was evaluated by studying 1, 1-diphenyl-2-picrylhydrazyl radical scavenging activity using the standard procedure. The leaf extract was screened for a major metabolite namely swertiamarin compound using HPLC.Results: The phytochemical analysis of leaf extract of E. littorale revealed the presence of significant secondary metabolites such as steroids, quinones, cardiac glycosides, saponins, tannins, phenols, flavonoids, terpenoids and alkaloids. The total phenol and terpenoid content in leaf extract were found to be 16. 32 mg gallic acid equivalents/g and 71. 0 mg/g respectively. The acetone leaf extract of E. littorale had showed significant radical scavenging activity. The results of -HPLC analysis in the leaf extract of E. littorale proved the presence of the active principle namely swertiamarin.Conclusion: It can be concluded that E. littorale leaf extract can be used as a potent source of natural antioxidant and thus could prevent many free radical mediated diseases. The validated HPLC method can be used for routine quality control analysis. © 2014 Asian Journal of Pharmaceutical and Clinical Research. All rights reserved.
Jayaraman P.,Government Arts College for Men Autonomous |
Mathivanan K.,Government Arts College for Men Autonomous |
Arumugam P.,Armats Biotech New
Journal of Bionanoscience | Year: 2013
Among the methods involved in synthesis of metal nanoparticals, biological methods of synthesis are currently gaining importance and reliable due to its cost effective, eco-friendly and usage of non-toxic materials in the processing. Therefore, the present study is focused on the synthesis of silver nanoparticles (SNPs) with leaf extract of holy plant Aegle marmelos Linn. by using 1 mM silver nitrate (AgNO3) solution. From the bio-reduction reaction mixture, the formation of SNPs was studied by UV-VIS spectrophotometer at the range of 390 nm to 500 nm and found maximum absorbance at 440 nm. The dried SNPs were characterized by using Transmission Electron Microscope (TEM) to observe the size, shape and distribution of particles and analyzed for confirmation of silver in SNPs by X-ray Diffraction (XRD) crystallographic method. Further, the SNPs were anlaysed for the protein or organic group by Fourier Transformed Infra Red (FTIR) spectrophotometer and found the peak of absorption at 500 to 700 nm. Finally, the antibacterial activity of SNPs were tested against few pathogenic and nonpathogenic bacteria like E.coli, Vibrio cholereae, Proteus vulgaris, Psuedomonas aurugenosa and Bacillus licheniformis by using standard methods and the results indicates that the SNPs alone treated has inhibited the bacteria at mild to moderate level in E.coli and Vibrio cholerae. However, the SNPs mixed with antibiotics inhibited the growth of all the species of bacteria tested. From the present study, it was concluded that the plant leaf extracts from Aegle marmelos Linn. can be used as a bio-reductant for the synthesis of SNPs which is environmental friendly and cost effective method. By standardizing the biosynthesis method, SNPs can be prepared in bulk with safe process environment and it can be used for various medical applications including control of pathogenic microorganisms. Copyright © 2013 American Scientific Publishers. Website © 2013 Publishing Technology.