Entity

Time filter

Source Type


Veghari G.,Golestan University of Medical Sciences
Journal of Research in Health Sciences | Year: 2013

related factors based on three ethnic groups among primary school children in north of Iran in 2010. Methods: This cross-sectional study was carried out through multistage cluster random sampling on 5698 subjects (2505 Fars-native, 2154 Turkman, and 1039 Sistani) in 112 schools. Well-trained staffs completed the questionnaire and measured students' weight and height. Malnutrition estimated the Z-score less than -2SD for underweight, stunting and wasting were calculated using the cutoffs from WHO references. Results: Generally, malnutrition was observed in 3.20%, 4.93% and 5.13% based on underweight, stunting and wasting respectively. It was more common in girls than in boys and in Sistani than in other ethnic groups. The correlation between malnutrition based on underweight and stunting and ethnicity was statisti-cally significant (P=0.001). Results of logistic regression analyses showed that the risk of malnutrition was in rural area 1.34 times more than urban area, in girls 1.17 times more than boys, in Sistani ethnic group 1.82 times more than Fars-native ethnic group, in low economic families 2.01 times more than high economic families. Conclusion: Underweight, stunting and wasting are the health problems in primary school children in north of Iran with a higher prevalence in girls, in rural areas, and in Sistani ethnic group. Source


Mansourian A.R.,Golestan University of Medical Sciences
Pakistan Journal of Biological Sciences | Year: 2012

Thyroid hormones play an important role on the cardiovascular systems and thyroid disorder ultimately have a profound adverse effects on myocardium and vascular functions. There are extensive reports on the role of overt thyroid dysfunction which adversely can modify the cardiovascular metabolism but even at the present of some controversial reports, the subclinical thyroid disorders are able also to manipulate cardiovascular system to some extent. The aim of this study is to review the cardiovascular disorders accompanied with subclinical hypothyroidism. It is concluded that adverse effect of thyroid malfunction on myocardium and vascular organs are through the direct role of thyroid hormone and dyslipidemia on heart muscle cells at nuclear level and vascular system, respectively. It seems many cardiovascular disorders initially would not have been occurred in the first place if the thyroid of affected person had functioned properly, therefore thyroid function tests should be one of a prior laboratory examinations in cardiovascular disorders. © 2012 Asian Network for Scientific Information. Source


Mansourian A.R.,Golestan University of Medical Sciences
Pakistan Journal of Biological Sciences | Year: 2011

Iodine is in the crucial parts of two hormones of T4 and T3 produced by the thyroid glands which are essential for all the aspects of human metabolisms. It is demonstrated that iodine deficiency can be considered as sole cause of many thyroid abnormalities including mental disorders. Iodine deficiency of sufficient degree to cause hypothyroidism during fetus life and early infancy will be accompanied with brain abnormality possibly to the stage of mental retardation. The iodine deficiency among subjects in their early stage of childhood is not as severe as those in their fetus or infancy. In adult subjects the sever iodine deficiency can be also associated with mental disorders due to the direct side effects of hypothyroidism occurred by lack of iodine. The clinical manifestation of iodine deficiency show itself with psychological disorders in adult subjects. The status of iodine within blood can be evaluated through measurement of urinary iodine level and the low urinary concentration is an indicative of hypothyroidism. Mental retardation and brain damage due to iodine deficiency can be prevented if iodine supplementation prescribed duly on time. © 2011 Asian Network for Scientific Information. Source


Mansourian A.R.,Golestan University of Medical Sciences
Pakistan Journal of Biological Sciences | Year: 2010

This literature review was conducted to summarize the main points of maternal thyroid function tests, with particular attention in the first trimester of pregnancy which accompanied with significant biochemical and metabolic alteration. The evaluation of thyroid function of either hyperthyroidism and hypothyroidism should be assessed by determination of serum Thyroid Stimulating Hormone (TSH), Thyroxine (T4), Triiodothyronine (T3), Iodine and Thyroid Autoantibodies. Glomerular filtration rate is increased during pregnancy; therefore iodine deficiency should be evaluated during the pregnancy to prevent hypothyroidism. The role which can be played by Human Chronic Gonadotropin (hCG) on stimulating the thyroid gland to become over-active was investigated. Serum level of thyroglobulin (Tg) and Thyroxin Binding Globulin (TBG) should be assessed for proper assessments of thyroid gland during pregnancy. Thyroid function tests during first-trimester of pregnancy and particularly the reference interval for thyroid function tests for pregnant women in each region has to be established, to prevent mis-diagnosis and irreversible mental and physical adverse affect for growing fetus. © 2010 Asian Network for Scientific Information. Source


Mansourian A.R.,Golestan University of Medical Sciences
Pakistan Journal of Biological Sciences | Year: 2010

Thyroid disorders usually associated with lipid abnormalities. Overt hypothyroidism is a state with thyroid hormone deficiency. Sub clinical hypothyroidism is defined as condition, in which thyroid stimulating hormone concentration elevated when serum thyroid hormones are at normal levels. Whether sub-clinical hypothyroidism associated with lipid alteration, it is the main concept behind this study. Although, in this study, we found cases with normal thyroxin and elevated thyroid stimulating hormone are common, but whether the sub-clinical hypothyroidism finally converted to overt hypothyroidism are not universally accepted. The findings also indicated subjects with sub-clinical hypothyroidism usually are accompanied with dyslipidemia and in general the total cholesterol level is higher among sub-clinical hypothyroid patients, with eventual risk of arthrosclerosis. This study indicated that there is not a common findings to support the benefit of thyroxin therapy in sub-clinical hypothyroidism. It is concluded that it seems sub-clinical hypothyroidism is a common thyroid abnormality which can be diagnosed by the medical diagnostic laboratory through thyroid function test and it is mainly accompanied with lipid disorder. © 2010 Asian Network for Scientific Information. Source

Discover hidden collaborations