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Huh D.N.,University of California at Irvine | Czer E.T.,University of Kansas | Cordova K.E.,Berkeley Global Science Institute | Chow W.I.,University of San Diego | And 3 more authors.
Inorganica Chimica Acta | Year: 2016

The complex Ru((R,R)-DACH-Naph)Cl2 ((R,R)-2), a neutral Ru(II) complex of the Trost diamido-bis(phosphine) ligand ((R,R)-DACH-Naph (H21)) was synthesized in 86% yield via the direct stoichiometric reaction of H21 and RuCl2(DMSO)4 in refluxing toluene. Complex (R,R)-2 was further reacted with excess [NO][BF4] producing Ru((HON)2-DICH-Naph)Cl2 (4) in 48% yield; a Ru(II) complex where the Trost ligand has been oxidized to a diimine and nitrosylated, on the backbone cyclohexyl ring, to a dioxime. The structures of (R,R)-2 and 4 were revealed in the solid state by single-crystal X-ray analysis and in the solution state via 1H NMR spectroscopy.


Lee S.,University of California at Berkeley | Lee S.,Lawrence Berkeley National Laboratory | Lee S.,Kavli Energy NanoSciences Institute | Lee S.,Berkeley Global Science Institute | And 9 more authors.
Science | Year: 2016

A chiral metal-organic framework, MOF-520, was used to coordinatively bind and align molecules of varying size, complexity, and functionality. The reduced motional degrees of freedom obtained with this coordinative alignment method allowed the structures of molecules to be determined by single-crystal x-ray diffraction techniques. The chirality of the MOF backbone also served as a reference in the structure solution for an unambiguous assignment of the absolute configuration of bound molecules. Sixteen molecules representing four common functional groups (primary alcohol, phenol, vicinal diol, and carboxylic acid), ranging in complexity from methanol to plant hormones (gibberellins, containing eight stereocenters), were crystallized and had their precise structure determined. We distinguished single and double bonds in gibberellins, and we enantioselectively crystallized racemic jasmonic acid, whose absolute configuration had only been inferred from derivatives.

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