Stevenage, United Kingdom
Stevenage, United Kingdom

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Patent
Glaxo Group Ltd | Date: 2015-06-02

A package which can be torn open by a user, comprising a polymer film material having a preferential tearing direction and defining a cavity for a product, wherein the polymer film material incorporates a bias facilitating tearing along a tear line oriented in a direction other than its preferential tearing direction and a tear initiation location which facilitates tearing of the polymer film material in its preferential tearing direction to open the package, the tear line being adjacent to a tear initiation location. The polymer film material having a preferential tearing direction provides resistance against a child tearing open the package.


Patent
Glaxo Group Ltd | Date: 2016-10-14

The present invention is directed to antigen binding constructs comprising one or two epitope binding domains separated by a single chain Fc region of an antibody, wherein each epitope binding domain in capable of binding to VEGF, to dimers comprising two antigen binding constructs of the invention, pharmaceutical compositions comprising said dimers and their use in the treatment of diseases associated with VEGF signalling, such as diabetic macular edema (DME), wet age-related macular degeneration (Wet AMD), diabetic retinopathy, retinal vein occlusion (RVO), and corneal neovascularisation, and polynucleotide sequences encoding said antigen binding constructs.


Patent
Glaxo Group Ltd | Date: 2016-10-14

The present invention discloses humanised anti-IL-18 antibodies, methods of manufacture, and methods of treatment with said antibodies. Further disclosed are screening methods using for example surface plasmon resonance to identify antibodies with therapeutic potential.


Patent
Glaxo Group Ltd | Date: 2016-12-01

The present invention is directed to novel retinoid-related orphan receptor gamma (ROR) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by ROR.


Patent
Glaxo Group Ltd | Date: 2017-01-04

Muscarinic Acetylcholine Receptor Antagonists and therapeutic methods of using them are provided.


Patent
Glaxo Group Ltd | Date: 2016-11-15

Compounds of formula (I): wherein;


Patent
GLAXO GROUP Ltd | Date: 2017-02-09

The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanising antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.


Patent
Glaxo Group Ltd | Date: 2017-04-12

A package (10, 20, 30, 40, 50) which can be torn open by a user, comprising a polymer film material having a preferential tearing direction and defining a cavity for a product, wherein the polymer film material incorporates a bias (16, 24, 35, 56) facilitating tearing along a tear line oriented in a direction other than its preferential tearing direction and a tear initiation location (18, 26, 37, 41, 58) which facilitates tearing of the polymer film material in its preferential tearing direction to open the package, the tear line being adjacent to a tear initiation location. The polymer film material having a preferential tearing direction provides resistance against a child tearing open the package.


Patent
Glaxo Group Ltd | Date: 2017-02-01

A dispensing container (10) for extrudable fluid materials having a collapsible tubular body (11) with a dispensing nozzle (15) at one end (11A) and the opposite end (11B) being closed with an end wall member (20) biased to fold about a fold axis transverse to the longitudinal direction of the tubular body, wherein the end wall member either comprises a wall part of which two surfaces (81A, 81B) enclose a concave angle between them and being foldable about a fold axis in the direction of the length of the valley or the end wall member bulges convexly in a generally conical shape.


Patent
Glaxo Group Ltd | Date: 2016-08-19

A compound of formula (I):

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