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Chhabra J.K.,National Institute of Technology Kurukshetra | Kumar D.,GJUS and T
Journal of Computational Science | Year: 2014

This paper presents a parameter adaptive harmony search algorithm (PAHS) for solving optimization problems. The two important parameters of harmony search algorithm namely Harmony Memory Consideration Rate (HMCR) and Pitch Adjusting Rate (PAR), which were either kept constant or the PAR value was dynamically changed while still keeping HMCR fixed, as observed from literature, are both being allowed to change dynamically in this proposed PAHS. This change in the parameters has been done to get the global optimal solution. Four different cases of linear and exponential changes have been explored. The change has been allowed during the process of improvization. The proposed algorithm is evaluated on 15 standard benchmark functions of various characteristics. Its performance is investigated and compared with three existing harmony search algorithms. Experimental results reveal that proposed algorithm outperforms the existing approaches when applied to 15 benchmark functions. The effects of scalability, noise, and harmony memory size have also been investigated on four approaches of HS. The proposed algorithm is also employed for data clustering. Five real life datasets selected from UCI machine learning repository are used. The results show that, for data clustering, the proposed algorithm achieved results better than other algorithms. © 2013 Elsevier B.V. Source


Goyat A.,GJUS and T
Proceedings - 2012 2nd International Conference on Advanced Computing and Communication Technologies, ACCT 2012 | Year: 2011

Printing is an art of duplication. Infact it is an art, science & technology of reproduction of 'n' number of replicas of an original/literature/ catalogue etc. with the help of a suitable printing process on the desired substrate and surface. It is declared as the "Greatest Invention of Millennium" by Time magazine, USA. And the spectrum of Time magazine is very well known. It is the largest industry of India after auto-parts. We are basically a servicing industry being overlapped by various perspectives of Engineering and Sciences like Computers, Electronics, Manufacturing, Chemical, Electrical, Optical and, of course by Management aspects. By an large, any Printing and Packaging concern is divided into three main sections - Pre-press, In-press and Post-press. In other words, In-press and Post-press are meant for Hardcore Printing and Binding & Finishing works respectively. Pre-press section is there to take care of all tasks required to prepare an Image-carrier. The work in any typical Pre-press section starts with the preparation of copy that is required to be reproduced. Nonetheless, computers & their applications are an indispensable part of our Pre-press jobs. Generally, Desk-Top Publishing software like Quark X-press, Illustrator, Corel-Draw, Fox-Pro, Prinect (Heidelberg), Photoshop, Adobe In-design, Adobe PageMaker, MS-Office etc. etc. are used in Pre-press works. The Console/Control mechanism present in Printing machines (In-press section) and Bindery equipments (Post-press section) are also using various Computer technologies. © 2012 IEEE. Source


Chhabra J.K.,National Institute of Technology Kurukshetra | Kumar D.,GJUS and T
Advances in Intelligent Systems and Computing | Year: 2014

Distance measure plays a vital role in clustering algorithms. Selecting the right distance measure for a given dataset is a challenging problem. In this paper, the effect of six distance measures on three clustering algorithms, K-means, single linkage, and average linkage is investigated. The distance measures include Euclidean, Euclidean squared, Manhattan, Mahalanobis, cosine similarity, and Pearson correlation. We describe all the distance measures pointing out their strengths and weaknesses. The performance of clustering algorithms on distance measures are evaluated on two artificial and four real-life datasets. Experimental results show the impact of distance measures when used for different datasets. © Springer India 2014. Source


Kumar S.,P.A. College | Tyagi D.K.,P.A. College | Gupta A.,GJUS and T
Asian Journal of Pharmaceutical and Clinical Research | Year: 2010

Prodrug strategy is an established part of drug development. The present work is aimed to synthesis some novel prodrugs of Naproxen. Seven ester derivatives of Naproxen have been synthesized via acid alcohol coupling of Naproxen and alcohol derivatives in dichloromethane medium. These newly synthesized prodrugs were analyzed by NMR and IR spectroscopy. All the compounds were evaluated for anti-inflammatory activity by Carragennan Induced Rat hind Paw method and analgesic activity by acetic acid induced writhing. Source


Singh S.,GJUS and T
International Journal of Pharma and Bio Sciences | Year: 2014

Inspite of progress in diagnosis, treatment prostate cancer has become one of the most frequent lethal cancers in males. Rate of detection of prostate cancer varies widely across the world. Research on molecular biology of prostate cancer is expected to give new insight of improving, distinguishing slow growing from aggressive clinically relevant cancers and provide target for treatment. Traditionally, prostate cancer research focused on prostate structure, development and hereditary aspects. This review mainly focuses on novel finding of genetics and molecular biological aspects of the prostate cancer like alteration of androgen signaling, investigation of the tumor suppressor gene, proto Oncogenes and studies of chromosomal alteration followed by telomerase activity. Source

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