Givaudan | Date: 2017-02-01
A malodour-counteracting composition comprising(i) a salt of general formula (I)R_(1)R_(2)R_(3)R_(4)N^(+) X^(-)(I)wherein R_(1),R_(2), R_(3), R_(4) are independently selected from C_(1-4) alkyl, or R_(1), R_(2), R_(3), R_(4) may together constitute a nitrogen-containing cyclic system in which the nitrogen is part of a pyridinium or an imidazolinium ring; and X- is a counterion characterised by its protonated form having an acidity constant (pKa) lying between 1 and 6; and(ii) an alpha, beta-unsaturated carbonyl compound of the general formulaR_(5)R_(6)C=CR_(7)C(=O)YR_(8)(II)in which R_(5), R_(6), R_(7), R_(8) and Y are selected such that;(a) R_(5), R_(6), R_(7), R_(8) are independently selected from hydrogen and C_(1-10) hydrocarbyl residues which may be saturated, unsaturated, aromatic, cyclic, branched or unbranched, and which are optionally substituted, and Y is a covalent bond; or(b) at least one of R_(5) and R_(6) is an ester group, the other and R_(7) are selected as described in (a) and Y is oxygen, such that the compound is a di-ester or tri-ester. The composition may be incorporated into consumer products and is able to remove malodours from the air or from surfaces.
Givaudan | Date: 2017-01-04
The present invention relates to a process for the production of formyl cyclohexene derivatives which are suitable as odorants as such or as intermediates for the preparation of further odorants. In particular the present invention relates to a domino-methylenation-Diels-Alder reaction of ,-unsaturated aldehydes using formaldehyde in the presence of 1,3-butadienes. Compounds of Formula (IVa) and their use as flavor or fragrance as well as compounds of Formula (IVb) are also claimed.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: BIOTEC-3-2014 | Award Amount: 11.39M | Year: 2015
Oxygen functionalities are key functional groups in many of todays chemicals and materials. The efficient introduction of oxygen-functionalities into raw materials are key chemical transformations in bulk and fine chemicals. Innovative bio-catalytic oxidation routes using molecular oxygen (from air) under benign and mild (pH) conditions such as ambient temperature and pressure can greatly improve the sustainability and economics of processes, but were so far mainly been applied in the pharma segments. In this segment, the enzyme-catalyzed step often represents the highest added value and the high price of the end-product (> 1000/kg) justifies less than optimal enzyme production and limitations in its catalytic efficiency. In order to achieve the widening of industrial application of enzymatic bio-oxidation processes to also larger volume but lower price chemical markets, ROBOX will demonstrate the techno-economic viability of bio-transformations of four types of robust oxidative enzymes: P450 monooxygenases (P450s), Baeyer-Villiger MonoOxygenase (BVMOs), Alcohol DeHydrogenase (ADH) and Alcohol OXidase (AOX) for which target reactions have already been validated on lab-scale in pharma, nutrition, fine & specialty chemicals and materials applications. ROBOX will demonstrate 11 target reactions on large scale for these markets in order to prepare them for scale up to commercial-scale plants. ROBOX is industry-driven with 2 major industrial players and 6 SMEs. It will assess the potential of technologies applied to become platform technologies technologies (multi-parameter screening systems, computational methodologies, plug bug expression systems) for broad replication throughout the chemical industry. The markets addressed within ROBOX represent a joint volume of over 6.000 ktons/year. The introduction of bio-oxidation processes is expected to bring substantial reductions in cost (up to -50%), energy use (-60%), chemicals (-16%) and GHG-emissions (-50%).
Givaudan | Date: 2016-08-12
The invention relates to organic compounds having the ability to reduce or suppress the onset of skin irritation induced by extraneous cause selected from the group of 2-heptylcyclopentanone, 2-ethoxynaphthalene; 2-methoxynaphthalene; 1-methoxy-4-(prop-1-enyl)benzene; 1-(cyclopropylmethyl)-4-methoxybenzene; Furthermore the invention refers to compositions for topical application to the skin comprising them. It further relates to a method of reducing or suppressing the formation of skin irritation.
Givaudan | Date: 2016-06-17
A method of providing a fragrant odour to an application, comprising the addition thereto of at least one compound of the formula I wherein X and Y are independently selected from the group consisting of CR^(1)R^(2)R^(3), NR^(4)R^(5 )and OR^(6), wherein R^(1 )to R^(5 )are selected from H and essentially hydrocarbon moieties that optionally comprise at least one oxygen, nitrogen or silicon atom, and R^(6 )is selected from essentially hydrocarbon moieties that optionally comprise at least one oxygen, nitrogen or silicon atom; and, A is an essentially hydrocarbon moiety that optionally comprises at least one oxygen, sulphur, nitrogen or silicon atom, with the proviso that the compound A-CHO is a fragrant aldehyde. The use of these compounds in laundry, household and personal care products confers a long-lasting freshness.
Givaudan | Date: 2016-09-26
A method of providing a cooling effect to a product includes the incorporation into the product of at least one compound of the formula I in which m is a number between 0 and 2, X, Y and Z are selected independently from the group consisting of H, halogen, OH, Me, Et, MeO and EtO, and R^(1), R^(2 )and R^(3 )together comprise at least 6 carbons, selected such that The compounds confer substantial cooling effects on compositions applied to the skin or taken orally, such as toothpastes, mouthwashes, foodstuffs, beverages, confectionery, tobacco products, skin creams and ointments.
Givaudan | Date: 2016-03-29
Disclosed are compounds that block off-notes in consumables and methods of blocking off-notes in consumables including off-notes provided by sweeteners shuch as stevioside, swingle extract, glyccerhizin, perillartine, naringin dihydrochalcone, neohesperidine dihydrochalcone, mogroside V, rubusoside, rubus extract, and rebaudioside A, and artificial sweeteners such as aspartame, saccharin, acesulfame K (Acesulfame potassium), sucralose and cyclamate.
Givaudan | Date: 2016-04-29
The use of a fermented milk product comprising non-hydrolysed whey proteins which is substantially free of casein proteins for the purpose of improving skin firmness, by structuring collagen without promoting collagen synthesis, when topically applied to skin is provided.
Givaudan | Date: 2016-06-22
Perfume composition provided in the form of a plurality of dispersed perfume-containing droplets, suspended in an aqueous dispersing medium, said perfume droplets being mono-dispersed and having a diameter of 200 micrometres to 4000 micrometres, wherein said droplets comprise more than 60 wt %, of perfume ingredients, and wherein 25 wt % or less of said perfume ingredients are linear or branched alkyl alcohols and/or alkenyl alcohols; 10 wt % or less of the perfume ingredients are aldehydes; and 10 wt % or less of the perfume ingredients have a ClogP less than 2.1.
Givaudan | Date: 2016-07-27
Disclosed are nucleotide sequences encoding thioesterase enzymes, methods for their production, their use in methods to form thioesters, and their use in methods of screening for other wild type bacteria capable of producing said thioesterase enzymes. Also disclosed are compositions comprising thioesters produced by the methods disclosed herein.