Ginseng Research Center

Jecheon, South Korea

Ginseng Research Center

Jecheon, South Korea
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Ahn C.H.,Semyung University | Nam Y.M.,Semyung University | Nam Y.M.,Ginseng Research Center | Kim S.J.,Ginseng Research Center | And 4 more authors.
Korean Journal of Pharmacognosy | Year: 2016

This study was to evaluate the effect of ginseng (Panax ginseng) seed oil on the α-glucosidase and α-amylase. Each ginseng seed oils (HE, SE, EE) exhibited a significant inhibitory effect (p<0.001) at all concentrations (10 and 20 mg/ml) on α-glucosidase activity. HE is the highest inhibitory activity (86.92%) at a concentration of 20 mg/ml, SE and EE showed an inhibitory effect of 77.13% and 65.83%, respectively. And also, Each ginseng seed oils (HE, SE, EE) exhibited a significant inhibitory effect (p<0.001) at all concentrations (1 and 2 mg/ml) on α-amylase activity. HE is the highest inhibitory activity (89.68%) at a concentration of 2 mg/ml, SE and EE showed an inhibitory effect of 76.99% and 65.70%, respectively. © 2016, Korean Society of Pharmacognosy. All rights reserved.


Nam Y.M.,Semyung University | Nam Y.M.,Ginseng Research Center | Kwon J.H.,Semyung University | Hong J.T.,Semyung University | And 3 more authors.
Korean Journal of Pharmacognosy | Year: 2016

The purpose of this study is to develop a new preparation process of ginseng (Panax ginseng) flower buds extracts featuring high concentration of ginsenosides Rg2, Rg3, Rg5, F4 and Rh1, red ginseng special components. Chemical transformation from ginseng saponin glycosides to prosapogenin was analyzed by the HPLC. Extracts of ginseng flower buds were processed under several treatment conditions of ultrasonication (at 100°C). The results showed that the quantity of ginsenoside Rg6 increased by over 8.8% at the 16 hours of ultrasonication. Ginseng flower buds ethanol extract compared with other process times. The result of UGF-16 indicates that the ultrasonication processed ginseng flower buds extracts (at 100°C) treated for 16 hours produced the highest amount of ginsenoside F4 (8.833%), Rg3 (2.230%), Rg5 (2.339%) and Rg2 (1.002%). © 2016, Korean Society of Pharmacognosy. All rights reserved.


An H.J.,Semyung University | Nam Y.M.,Semyung University | Nam Y.M.,Ginseng Research Center | Yang B.W.,Korean Ginseng Research Co. | And 5 more authors.
Korean Journal of Pharmacognosy | Year: 2017

This study was carried out to obtain the basic information that can be used to index Acanthopanax in eleven species of China and Korea. The phytochemical components from the berry of Acanthopanax species, were measured by the HPLC analysis. Protocatechuic acid, eleutheroside B, eleutheroside E, scopolin, rutin, hyperoside, chiisanoside, oleanolic acid were found in ethanol extracts from the berry of Acanthopanax species. Total phenolic compound of Acanthopanax sessiliflorum f. chungbuensis berry (0.682%) was about seven times higher than those of Acanthopanax divaricatus f. distigmatis berry (0.091%). As a result, the order of the eleutheroside E content was 1) Acanthopanax sessiliflorum f. chungbuensis (0.554%), 2) A. divaricatus var. albeofructus (0.501%), 3) A. divaricatus f. flavi-flos (0.452%). And also, the order of the chiisanoside content was 1) Acanthopanax senticosus var. subinermis (8.434%), 2) A. seoulense (0.94%), 3) A. divaricatus f. flavi-flos (0.798%). © 2017, Korean Society of Pharmacognosy. All rights reserved.


Kim S.J.,Ginseng Research Center | Nam Y.M.,Ginseng Research Center | Nam Y.M.,Semyung University | Kim Y.M.,Semyung University | And 2 more authors.
Korean Journal of Pharmacognosy | Year: 2015

This study was to evaluate the effect of isopropyl alcohol fraction of ultrasonication processed ginseng flower buds(GFB-IF) on the collagen synthesis activity and inhibition of MMP-1 suppression in UV-irradiated human dermal fibroblasts. The higher contents of ginsenoside Rg2(8.234%), Rh1(5.749%), F4(3.881%) in isopropyl alcohol fraction of ginseng flower buds obtained by ultrasonication process at 600W(100°C) for 16 hours. GFB-IF had collagen synthesis effect. GFB-IF induced a significant dose-dependent decrease in the expression for MMP-1 protein. These results suggest that GFB-IF is a potential candidate for the prevention and treatment of wrinkle improving. © 2015, Korean Society of Pharmacognosy. All rights reserved.


Gwak H.H.,Semyung University | Hong J.T.,Semyung University | Ahn C.H.,Semyung University | Kim K.J.,Semyung University | And 8 more authors.
Natural Product Sciences | Year: 2015

The purpose of this study was to develop a new ginseng (Panax ginseng) flower buds extract with the high concentration of ginsenoside Rg3, Rg5, Rk1, Rh1 and F4, the Red ginseng special component. Chemical transformation from the ginseng saponin glycosides to the prosapogenin was analyzed by the HPLC. The ginseng flower buds were processed at the several treatment conditions of the ultrasonication (Oscillator 600 W, Vibrator 600W) and vinegar (about 14% acidity). The result of UVGFB-480 was the butanol fraction of ginseng flower buds that had been processed with ultrasonication and vinegar for 480 minutes gained the highest amount of ginsenoside Rg5 (3.548%), Rh1 (2.037%), Rk1 (1.821%), Rg3 (1.580%) and F4 (1.535%). The ginsenoside Rg5 of UVGFB-480 was found to contain 14.3 times as high as ginseng flower buds extracts (GFB, 0.249%). © 2015, Korean Society of Pharmacognosy. All rights reserved.


Yoon S.-H.,Semyung University | Nam Y.-M.,Semyung University | Nam Y.-M.,Ginseng Research Center | Hong J.-T.,Semyung University | And 3 more authors.
Journal of Ginseng Research | Year: 2016

The result of USRG-12 indicated that ultrasonication-processed (100°C, 12 h) red ginseng extracts had the highest amount of ginsenosides Rg3 (0.803%), Rg5 (0.167%), and Rk1 (0.175%). © 2016.

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