Ghent University is a highly ranked Dutch-speaking public university located in Ghent, Belgium. It is one of the larger Flemish universities, consisting of 41,000 students and 9,000 staff members. The current rector is Anne De Paepe . As of 2014, Ghent University ranks as 90th globally according to Times Higher Education, 129th according to QS World University Rankings and 70th according to the Academic Ranking of World Universities. It is therefore considered to be a top university, globally.It was established in 1817 by King William I of the Netherlands. After the Belgian revolution of 1830, it was administered by the newly formed Belgian state. French became the academic language until 1930, when Ghent University became the first Dutch-speaking university in Belgium. In 1991, the university was granted major autonomy and changed its name from State University of Ghent to its current name. Wikipedia.
Ghent University | Date: 2017-05-17
The present invention relates to hamamelitannin analogues, pharmaceutical compositions comprising the same, and combinations thereof with anti-microbial agents such as antibiotics or disinfectants. It in particular relates to the use of the compounds, compositions and combinations according to this invention in human or veterinary medicine, more in particular for use in the prevention and/or treatment of bacterial infections, such as Staphylococcus aureus infections, in humans or animals.
Vib Vzw and Ghent University | Date: 2017-05-17
The present invention relates to plants having a decreased expression of the KIX8 and KIX9 genes which result in an increased yield, particularly an increased leaf biomass. The invention provides plants and chimeric genes which can be used to decrease the combined KIX8/KIX9 gene expression.
Ghent University and Imec | Date: 2017-05-17
A photonic integrated circuit (10) comprises an input interface (12) adapted for receiving an optical input signal and splitting it into two distinct polarization modes and furthermore adapted for rotating the polarization of one of the modes for providing the splitted signals in a common polarization mode,. The PIC also comprises a combiner (16) adapted for combining the first mode signal and the second mode signal into a combined signal and a decohering means (15) adapted for transforming at least one of the first mode signal and the second mode signal such that the first mode signal and the second mode signal are received by the combiner in a mutually incoherent state. A processing component (17) for receiving and processing said combined signal is also comprised.
Koninklijke KPN N.V., Iminds and Ghent University | Date: 2017-01-25
A method of provisioning a service in a communication network is described, in which the service comprises at least one virtual network function and at least one virtual network path, which at least one virtual network function and at least one virtual network path are to be implemented in the communication network. The method comprises:- obtaining (202) affinity constraints and/or anti-affinity constraints relating to mapping the at least one virtual network path onto the communication network,- optionally obtaining (202) affinity constraints and/or anti-affinity constraints relating to mapping the at least one virtual network function onto the communication network, and- mapping (203) the at least one virtual network function and at least one virtual network path onto the communication network subject to said constraints.
Vib Vzw, Ghent University, The United States Of America and Dartmouth College | Date: 2017-02-01
The present invention relates to single domain antibodies that are directed against respiratory syncytial virus (RSV). More specifically, it relates to single domain antibodies that bind to the prefusion form of the fusion (F) protein of RSV. The invention relates further to the use of these single domain antibodies for prevention and/or treatment of RSV infections, and to pharmaceutical compositions comprising these single domain antibodies.
Ghent University | Date: 2017-01-18
The present invention relates to the field of molecular pathology (for example cancer diagnosis, prognosis, treatment and/or therapy prediction) through the detection of RNA, mutations, copy number changes and determination of the methylation status of specific sequences of the genome of individual patients in hybridization assays (southern blot, ISH, dot blot) including in situ determination of the methylation status of specific sequences of the genome of individual patients in individual cells. More specifically the present invention relates to: a) target-specific probes covalently-attached to a labeled tail, b) the synthesis method of said probe, c) the usage of said probe such as an in situ hybridization-based method to correlate the methylation status of a promoter region of a gene in a biopsy or cytology specimen of a patient to the morphology and localization in that specimen, and d) kits comprising said target-specific probes. The latter method and products allow detection of (epi) genetic changes in specific cell types of histological or cytological (cancer) specimens or on membranes which will contribute to scientific research and which will help physicians to accurately diagnose diseases and/or start an appropriate treatment.
Ghent University and Allnex Belgium S.A. | Date: 2017-01-11
The invention pertains to the technical field of urethane based materials, in particular to radiation curable urethane precursors that are cross-linkable in solid form and materials obtainable therefrom. In addition the invention pertains to methods for manufacturing these precursors and materials, and their uses. The invention is advantageous to the fields of i.e. coatings and biomedical applications.
Imec and Ghent University | Date: 2017-03-22
A method for optically and mechanically coupling an optical fiber to an optical or optoelectronic component on a substrate is provided. The method comprises: providing an optical fiber comprising a core and a cladding, the core being exposed at an end face of the optical fiber; forming a polymer waveguide core on the end face, the polymer waveguide core extending from the fiber core; bringing the polymer waveguide core in proximity of the optical or optoelectronic component; providing a liquid optical material, the liquid optical material embedding the polymer waveguide core; and curing the liquid optical material, thereby forming a polymer cladding layer encapsulating the polymer waveguide core and mechanically attaching the optical fiber to the optical or optoelectronic component.
Ghent University and Vib Vzw | Date: 2017-02-08
The present invention provides compositions and methods comprising a sialoadhesin binding moiety for treating metabolic and genetic bone disease, especially for treating a bone disorder of hyperresorption of bone and/or enhanced activation of osteoclasts.
Lamkanfi M.,Ghent University
Nature Reviews Immunology | Year: 2011
Caspase 1 activation by inflammasome complexes in response to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) induces the maturation and secretion of the pro-inflammatory cytokines interleukin-1β (IL-11β) and IL-18. Recent reports have begun to identify additional inflammasome effector mechanisms that proceed independently of IL-11 βand IL-18. These include the induction of pyroptotic cell death, the restriction of bacterial replication, the activation of lipid metabolic pathways for cell repair and the secretion of DAMPs and leaderless cytokines. These non-canonical functions of caspase 1 illustrate the diverse mechanisms by which inflammasomes might contribute to innate immunity, repair responses and host defence. © 2011 Macmillan Publishers Limited. All rights reserved.