Soni A.,GGS Medical College and Hospital |
Saini R.,Shivam Multispecialty Hospital |
Gulati A.,Shivam Multispecialty Hospital |
Paul R.,GGS Medical College and Hospital |
And 2 more authors.
Journal of Arthroplasty | Year: 2014
Tranexamic acid is an antifibrinolytic drug used widely to prevent bleeding. Its use in reducing bleeding during total knee arthroplasty surgery is well proven but there is no final consensus regarding the regimen. The purpose of our study was to compare the effectiveness of intravenous and intra-articular regimen of tranexamic acid during the total knee arthroplasty surgery. A total of 40 patients were received three doses of intravenous tranexamic acid during total knee arthroplasty surgery. Intra-articular tranexamic acid was used in 40 patients during the surgery. We concluded that intra-articular tranexamic acid is equally effective as three dose intravenous regimen in reducing blood loss during total knee arthroplasty surgery. © 2014 Elsevier Inc.
Jindal K.C.,Ggs Medical College And Hospital |
Singh G.P.,Ggs Medical College And Hospital |
Munjal V.,Ggs Medical College And Hospital
International Journal of Psychiatry in Clinical Practice | Year: 2013
Objective. The aim of the study was to compare efficacy and tolerability of aripiprazole with olanzapine in the short-term treatment of schizophrenia in an Indian population. Method. This was a randomized double-blind controlled study comparing aripiprazole and olanzapine in the treatment of individuals with schizophrenia in an inpatient clinical setting. Sixty subjects between 18 and 65 years of age, who fulfilled the ICD-10 criteria for schizophrenia, were enrolled. Patients' detailed demographic and clinical evaluation was conducted and they were administered efficacy assessment scales (BPRS, PANSS) and safety assessments scale (Simpson Angus Scale, UKU side effect rating scale) at regular intervals of 1 week each throughout the study. The laboratory tests (complete haemogram, electrocardiogram (ECG), lipid profile, liver and renal function tests) were conducted at baseline and after 1-week intervals until 6 weeks of treatment. The patients were randomly allocated to receive either aripiprazole or olanzapine. Results. Both aripiprazole and olanzapine led to significant reductions on BPRS and PANSS total score over a period of 6 weeks. Weight gain was observed more frequently in the olanzapine-treated group (22.20%) as compared to aripiprazole (7.70%). More patients in the aripiprazole treatment group required comedications (trihexiphenidyl and lorazepam) than olanzapine recipients. Conclusion. This study demonstrates that aripiprazole is equally efficacious as olanzapine in the treatment of schizophrenia. Aripiprazole has a more benign side effect profile (weight gain, blood sugar level, lipid profile) as compared to olanzapine in the short-term treatment of schizophrenia. This study is the first in an Indian population to have compared aripiprazole and olanzapine. © 2013 Informa Healthcare.
Talwar A.,Ggs Medical College And Hospital |
Puri N.,Ggs Medical College And Hospital |
Singh M.,Ggs Medical College And Hospital
International Journal of STD and AIDS | Year: 2010
The Buschke-Loẅenstein tumour is an extremely rare, slow-growing, locally destructive, cauliflower-like mass, also known as giant condyloma acuminatum. We report a case of a 42-year-old man who presented to the department of surgery with a two-year history of a perineal tumour. The mass was painless initially but had become painful more recently. After histopathological confirmation, the tumour was removed surgically, as it was resistant to medical treatment. There has been considerable debate regarding the exact nature, aetiology and treatment of these lesions.
Puri N.,Ggs Medical College And Hospital |
Mahajan B.B.,Ggs Medical College And Hospital
Journal of Pakistan Association of Dermatologists | Year: 2014
Objectives: To document various biochemical parameters like serum calcium, uric acid etc. and correlate them clinically. Patients and methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proven psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results: There were significant alterations in different biochemical values in patients before and after treatment. With clinical improvement there was shift of biochemical parameters towards normal value. Hyperuricemia was seen in 16% patients and hypocalcaemia was seen in 10% of patients. Conclusions: With improvement of clinical picture, a shift of biochemical values towards normal was recorded.
Kumar S.,Ggs Medical College And Hospital |
Sidhu S.,Ggs Medical College And Hospital |
Mahajan B.B.,Ggs Medical College And Hospital
Annals of Dermatology | Year: 2013
Touraine-Soulente-Golé Syndrome (TSG) or pachydermoperiostosis is a rare disorder characterized by pachydermia, periostosis & digital clubbing. Herein, we report a case of a 27 year old male, with the looks of a 47 year old. He presented with excessive wrinkling on his face since past 8 years. TSG syndrome was suspected and examined by histopathological, endocrinological and radiological studies for the confirmation of clinical diagnosis.
Kaur S.,GGS Medical College and Hospital |
Mahajan B.B.,GGS Medical College and Hospital
Indian Journal of Dermatology | Year: 2015
Eyelash trichomegaly is increased length, curling, pigmentation or thickness of eyelashes. Various causes include congenital syndromes, acquired conditions and drugs. It can manifest at birth or present later in life. It can form a part of spectrum of manifestations of some congenital syndromes. Although it tends to have a benign course, it can lead to psychological disturbances and can result in corneal abrasions and visual disturbances, if trichiasis occurs. This article focuses on its etiology, pathogenesis and brief management.
Kaur P.,GGS Medical College and Hospital |
Basu S.,Government Medical College and Hospital |
Kaur G.,Government Medical College and Hospital |
Kaur R.,Government Medical College and Hospital
Journal of Emergencies, Trauma and Shock | Year: 2011
Blood and blood components are considered drugs because they are used in the treatment of diseases. As with any drug, adverse effects may occur, necessitating careful consideration of therapy. Like any other therapeutic decision, the need for transfusion should be considered on the basis of risks and benefits and alternative treatments available to avoid over- and under-transfusion. This review is focused on the blood transfusion protocol in trauma patients with hemorrhagic shock. Besides, issues related to emergency and massive transfusion have also been elaborated. We conducted a comprehensive MEDLINE search and reviewed the relevant literature, with particular reference to emergency medical care in trauma.
Kaur H.,GGS Medical College and Hospital |
Khetarpal R.,GGS Medical College and Hospital |
Aggarwal S.,GGS Medical College and Hospital
Journal of Clinical and Diagnostic Research | Year: 2013
Idiopathic dilated cardiomyopathy is a primary myocardial disease of unknown etiology characterized by left ventricular or biventricular dilation and impaired contractility. Depending upon diagnostic criteria used, the reported annual incidence varies between 5 and 8 cases per 100, 000 populations. Dilated cardiomyopathy is defined by presence of: a) fractional myocardial shortening less than 25% (>2SD) and/or ejection fraction less than 45% (>2SD) and b) Left Ventricular End Diastolic Diameter (LVEDD) greater than 117% excluding any known cause of myocardial disease. Such cases are always a challenge to the anesthesiologist as they are most commonly complicated by progressive cardiac failure. We report the anesthetic management of a patient with dilated cardiomyopathy undergoing surgery for carcinoma breast.
PubMed | Adesh Institute of Medical science and GGS Medical College and Hospital
Type: Journal Article | Journal: Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society | Year: 2016
Benign prostrate hyperplasia (BPH) is a leading source of healthcare problem in aging men around the world including India. Both International Prostate Symptom Score (IPSS) and New Visual Prostate Symptom Score (VPSS) are used to assess the lower urinary tracts symptoms (LUTSs) in men. The present study was planned to compare these two scores, IPSS and VPSS in Indian rural men prospectively and their efficacy was compared with urodynamic evaluation of the patients.With Institutional Ethical Committee approval, this study was conducted on 100 patients having LUTS and BPH after obtaining written informed consent. Patients educational status was noted. All the patients were requested to complete the IPSS and VPSS questionnaire, and they were correlated. The urodynamic study was performed on all the patients with uroflowmeter. Two parameters of uroflowmetry, QMost of the patients (55%) in this study were uneducated. Out of 100 patients, 83% were able to fill the VPSS questionnaire without assistance as compared to only 40% patients in IPSS questionnaire (VPSS correlates significantly with the IPSS to quantify the LUTS due to BPH. The VPSS can be used instead of the IPSS for the assessment of symptom severity in men with LUTS, who are illiterate or have limited education.
PubMed | GGS Medical College and Hospital
Type: Journal Article | Journal: Anesthesia, essays and researches | Year: 2016
Perioperative stress is an often ignored commonly occurring phenomenon. Little or no prior knowledge of anesthesia techniques can increase this significantly. Patients awaiting surgery may experience high level of anxiety. Preoperative visit is an ideal time to educate patients about anesthesia and address these fears. The present study evaluates two different approaches, i.e., standard interview versus informative audiovisual presentation with standard interview on information gain (IG) and its impact on patient anxiety during preoperative visit.This prospective, double-blind, randomized study was conducted in a Tertiary Care Teaching Hospital in rural India over 2 months.This prospective, double-blind, randomized study was carried out among 200 American Society of Anesthesiologist Grade I and II patients in the age group 18-65 years scheduled to undergo elective surgery under general anesthesia. Patients were allocated to either one of the two equal-sized groups, Group A and Group B. Baseline anxiety and information desire component was assessed using Amsterdam Preoperative Anxiety and Information Scale for both the groups. Group A patients received preanesthetic interview with the anesthesiologist and were reassessed. Group B patients were shown a short audiovisual presentation about operation theater and anesthesia procedure followed by preanesthetic interview and were also reassessed. In addition, patient satisfaction score (PSS) and IG was assessed at the end of preanesthetic visit using standard questionnaire.Data were expressed as mean and standard deviation. Nonparametric tests such as Kruskal-Wallis, Mann-Whitney, and Wilcoxon signed rank tests, and Students Patients IG was significantly more in Group B (5.43 0.55) as compared to Group A (4.41 0.922) (Audiovisual presentation provides unhurried, detailed, and reliable information about the perioperative environment and anesthesia procedure. This helps in significant IG and reduction of patient anxiety.