Georgia Regents University | Date: 2014-10-28
An apparatus and method for measuring the superposition of a plurality of sound waves propagating within a conduit containing a fluid having a plurality of transducers positioned substantially parallel to the flow direction along the wall of the conduit. The system includes a computing device for modeling the superposition of a plurality of sound waves as they propagate within the conduit.
Georgia Regents University | Date: 2014-08-29
A dual chamber bioreactor for producing complex, multilayer tissue, organs, organ parts, and skin replacements has been developed. The bioreactor is modular and incorporates a removable tissue culture cassette. By rotating the dual chamber bioreactor along the horizontal axis, different populations of cells with different growth requirements can be cultured on the different surfaces of the tissue culture cassette that are exposed to different media reservoirs. Culturing different populations of cells on different surfaces of the tissue culture cassette enables the production of multilayer tissue and organs. The tissue culture cassette can contain one or more discrete tissue culture sections.
Georgia Regents University | Date: 2013-01-14
Compositions for activating SGK-1 are provided. SGK-1 activators can be identified by the methods of screening provided herein. The SGK-1 activators can be used in the disclosed methods of reducing cell death and methods of treating ischemic-reperfusion injury. The ischemic-reperfusion injury can be due to a variety of complications resulting in blood loss to tissue and then the re-establishment of blood flow to the tissue.
Georgia Regents University, Montclair State University and Seton Hall University | Date: 2014-07-16
Compositions and methods of killing, inactivating, or otherwise reducing the spores such as bacterial spores are disclosed. The methods typically include reducing or preventing spore reactivation comprising contacting spores with an effective amount of one or more green tea polyphenols (GTP), one or more modified green tea polyphenols (LTP), or a combination thereof. In a preferred embodiment, the LTP is ()-epigallocatechin-3-gallate (EGCG) esterified at the 4 position with stearic acid, EGCG esterified at the 4 position with palmitic acid, or a combination thereof. The compositions and methods can be used in a variety of applications, for example, to increase the shelf-life of a food or a foodstuff, to reduce or delay the spoilage of a food or a foodstuff, or to decontaminate a device contaminated with spores.
Georgia Regents University | Date: 2015-10-26
An orthotic and assistive device for persons with disabilities is provided. The device is configured to allow the user to safely and more fully participate in conventional activities, such as riding a horse and a bicycle. Components of the device support the user and maintain the user in a desired form. Components of the device are inexpensively and quickly produced by 3D printing. As such, components can be custom fit for each user to enhance the effectiveness of the device.