The Georgia Institute of Technology is a public research university in Atlanta, Georgia, in the United States. It is a part of the University System of Georgia and has satellite campuses in Savannah, Georgia; Metz, France; Athlone, Ireland; Shanghai, China; and Singapore.The educational institution was founded in 1885 as the Georgia School of Technology as part of Reconstruction plans to build an industrial economy in the post-Civil War Southern United States. Initially, it offered only a degree in mechanical engineering. By 1901, its curriculum had expanded to include electrical, civil, and chemical engineering. In 1948, the school changed its name to reflect its evolution from a trade school to a larger and more capable technical institute and research university.Today, Georgia Tech is organized into six colleges and contains about 31 departments/units, with emphasis on science and technology. It is well recognized for its degree programs in engineering, computing, business administration, the science, architecture, and liberal arts.Georgia Tech's main campus occupies part of Midtown Atlanta, bordered by 10th Street to the north and by North Avenue to the south, placing it well in sight of the Atlanta skyline. In 1996, the campus was the site of the athletes' village and a venue for a number of athletic events for the 1996 Summer Olympics. The construction of the Olympic village, along with subsequent gentrification of the surrounding areas, enhanced the campus.Student athletics, both organized and intramural, are a part of student and alumni life. The school's intercollegiate competitive sports teams, the four-time football national champion Yellow Jackets, and the nationally recognized fight song "Ramblin' Wreck from Georgia Tech", have helped keep Georgia Tech in the national spotlight. Georgia Tech fields eight men's and seven women's teams that compete in the NCAA Division I athletics and the Football Bowl Subdivision. Georgia Tech is a member of the Coastal Division in the Atlantic Coast Conference. Wikipedia.
Emory University and Georgia Institute of Technology | Date: 2016-03-18
Various embodiments of the present invention provide a conduit system including an outer lumen, an inner lumen, and an attaching device. In other embodiments, a multiple access port device adapted for communication with at least one of an outer lumen, an inner lumen, or an attaching device of a conduit system is provided. In yet other embodiments, a system including an inner lumen that is collapsible is provided. Means for closing a conduit system are also provided, including a plug for insertion through an attaching device and a variable radius coiled member associated with an attaching device.
Georgia Institute of Technology | Date: 2015-04-24
A microneedle array is provided for administrating a drug or other substance into a biological tissue. The array includes a base substrate; a primary funnel portion extending from one side of the base substrate; and two or more solid microneedles extending from the primary funnel portion, wherein the two or more microneedles comprise the substance of interest. Methods for making an array of microneedles are also provided. The method may include providing a non-porous and gas-permeable mold having a two or more cavities each of which defines a microneedle; filling the cavities with a fluid material which includes a substance of interest and a liquid vehicle; drying the fluid material to remove at least a portion of the liquid vehicle and form a plurality of microneedles that include the substance of interest, wherein the filling is conducted with a pressure differential applied between opposed surfaces of the mold.
Georgia Institute of Technology | Date: 2016-09-06
Methods of making various capillary foams are provided. The foams can include liquid foams having a plurality of particles connected by a network of a secondary fluid at the interface between the discontinuous and continuous phase. The foams can also include solid foams where the continuous phases (bulk fluid) is removed to produce the solid foam having high overall porosities and low densities. Densities as low as 0.3 g cm^(3 )and porosities as high as 95% or higher can be achieved. The secondary fluid can be polymerized to further strengthen the solid foam. Methods and devices are also provided for oil recovery from water using a capillary foam. The methods can include forming a capillary foam wherein the oil is the secondary fluid, and wherein the foam can transport the oil to the surface of the water.
Georgia Institute of Technology | Date: 2016-10-31
A generator includes a first member, a second member and a sliding mechanism. The first member includes a first electrode and a first dielectric layer affixed to the first electrode. The first dielectric layer includes a first material that has a first rating on a triboelectric series. The second member includes a second material that has a second rating on the triboelectric series that is different from the first rating. The second member includes a second electrode. The second member is disposed adjacent to the first dielectric layer so that the first dielectric layer is disposed between the first electrode and the second electrode. The sliding mechanism is configured to cause relative movement between the first member and the second member, thereby generating an electric potential imbalance between the first electrode and the second electrode.
Georgia Institute of Technology | Date: 2015-05-05
Systems and methods for controlling a swarm of mobile robots are disclosed. In one aspect, the robots cover a domain main of interest. Each robot receives a density function indicative of at least one area of importance in the domain of interest, and calculates a velocity vector based on the density function and a displace vector relative to an adjacent robot. Each robot moves to the area of importance according to its velocity vector. In some aspects, the robots together perform a sequence of formations. Each robot mimics a trajectory as part of its performance by switching among a plurality of motion modes. Each robot determines its next motion mode based on a displacement vector relative to an adjacent robot.
Georgia Institute of Technology | Date: 2016-08-09
A method for cleaning patch-clamp glass pipette electrodes that enables their re-use. By immersing pipette tips or planar patch clamp chips into a detergent, followed by rinsing, pipettes and planar patch clamp chips were re-usable at least ten times with little to no degradation in signal fidelity, in experimental preparations ranging from human embryonic kidney cells to neurons in culture, slices, and in vivo.
Georgia Institute of Technology | Date: 2016-08-17
The present disclosure provides compositions including thermo-electro-chemical converter, methods of converting thermal energy into electrical energy, and the like. In general, embodiments of the present disclosure can be used to convert thermal energy into electrical energy by way of a chemical process.
Sherrill C.D.,Georgia Institute of Technology
Accounts of Chemical Research | Year: 2013
Fundamental features of biomolecules, such as their structure, solvation, and crystal packing and even the docking of drugs, rely on noncovalent interactions. Theory can help elucidate the nature of these interactions, and energy component analysis reveals the contributions from the various intermolecular forces: electrostatics, London dispersion terms, induction (polarization), and short-range exchange-repulsion. Symmetry-adapted perturbation theory (SAPT) provides one method for this type of analysis.In this Account, we show several examples of how SAPT pro-vides insight into the nature of noncovalent π-interactions. In cation-π interactions, the cation strongly polarizes electrons in π-orbitals, leading to substantially attractive induction terms. This polarization is so important that a cation and a benzene attract each other when placed in the same plane, even though a consideration of the electrostatic interactions alone would suggest otherwise. SAPT analysis can also support an understanding of substituent effects in π-π interactions. Trends in face-to-face sandwich benzene dimers cannot be understood solely in terms of electrostatic effects, especially for multiply substituted dimers, but SAPT analysis demonstrates the importance of London dispersion forces. Moreover, detailed SAPT studies also reveal the critical importance of charge penetration effects in π-stacking interactions. These effects arise in cases with substantial orbital overlap, such as in π-stacking in DNA or in crystal structures of π-conjugated materials. These charge penetration effects lead to attractive electrostatic terms where a simpler analysis based on atom-centered charges, electrostatic potential plots, or even distributed multipole analysis would incorrectly predict repulsive electrostatics. SAPT analysis of sandwich benzene, benzene-pyridine, and pyridine dimers indicates that dipole/induced-dipole terms present in benzene-pyridine but not in benzene dimer are relatively unimportant. In general, a nitrogen heteroatom contracts the electron density, reducing the magnitude of both the London dispersion and the exchange-repulsion terms, but with an overall net increase in attraction.Finally, using recent advances in SAPT algorithms, researchers can now perform SAPT computations on systems with 200 atoms or more. We discuss a recent study of the intercalation complex of proflavine with a trinucleotide duplex of DNA. Here, London dispersion forces are the strongest contributors to binding, as is typical for π-π interactions. However, the electrostatic terms are larger than usual on a fractional basis, which likely results from the positive charge on the intercalator and its location between two electron-rich base pairs. These cation-π interactions also increase the induction term beyond those of typical noncovalent π-interactions. © 2012 American Chemical Society.
Merrill A.H.,Georgia Institute of Technology
Chemical Reviews | Year: 2011
There are several nomenclature systems for glycosphingolipids, and many compounds are still referred to by their historically assigned names. Some of the breakthroughs in understanding the functions of sphingolipids, especially with respect to cell signaling, have come from having the capacity to measure more than one bioactive subspecies so the correct signaling pathways can be sorted out, especially when the metabolites have opposite effects, such as ceramide versus S1P. The relationships are being explored as a way for cancer detection and targeting using Shiga toxin. The story for iGb3 is less clear because although it stimulates NKT cells and has been hypothesized to be a natural modulator of them, recent studies have found that the human iGb3 synthase gene contains several mutations that render its product nonfunctional. A number of physiological factors have also been found to modulate DES.
Wang Z.L.,Georgia Institute of Technology
Advanced Materials | Year: 2012
The fundamental principle of piezotronics and piezo-phototronics were introduced by Wang in 2007 and 2010, respectively. Due to the polarization of ions in a crystal that has non-central symmetry in materials such as the wurtzite structured ZnO, GaN and InN, a piezoelectric potential (piezopotential) is created in the crystal by applying a stress. Owing to the simultaneous possession of piezoelectricity and semiconductor properties, the piezopotential created in the crystal has a strong effect on the carrier transport at the interface/junction. Piezotronics is about the devices fabricated using the piezopotential as a "gate" voltage to tune/control charge carrier transport at a contact or junction. The piezo-phototronic effect is to use the piezopotential to control the carrier generation, transport, separation and/or recombination for improving the performance of optoelectronic devices, such as photon detector, solar cell and LED. This manuscript reviews the updated progress in the two new fields. A perspective is given about their potential applications in sensors, human-silicon technology interfacing, MEMS, nanorobotics and energy sciences. Piezotronics is about devices fabricated using the piezopotential as a "gate" voltage to tune/control charge carrier transport at a contact or junction. The piezo-phototronic effect is to use the piezopotential to control the carrier generation, transport, separation and/or recombination for improving the performance of optoelectronic devices, such as photon detectors, solar cells and LEDs. This manuscript reviews progress in these two new fields. A perspective is given about their potential applications in sensors, human-silicon technology interfacing, MEMS, nanorobotics, and energy sciences. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.