General Sir John Kotelawala Defence University
General Sir John Kotelawala Defence University
Pushpakumara B.H.J.,General Sir John Kotelawala Defence University |
De Silva S.,Ruhuna University |
De Silva G.H.M.J.S.,Ruhuna University
International Journal of Structural Engineering | Year: 2017
Remediation of concrete bridges is an essential requirement of any country. Objectives of this study are to develop a novel condition rating method for existing concrete bridges and to validate the method by assessing condition of bridges. Condition of 18 concrete bridges was assessed from Bentota to Matara, Southern Province in Sri Lanka. Non-destructive tests (NDT) were used to assess the condition of concrete bridges. Standard eigenvectors were obtained from comparison matrices which were developed by using analytical hierarchy process (AHP) to determine the priority weight of each data. Element condition index (ECI) of all elements was separately calculated and overall bridge condition index (OBCI) was determined with adding element significant factor (ESF), element construction type factor (ECTF) and causal factor (CF). Finally, bridge soundness score (BSS) was determined and was used to conclude bridge remediation plan. The proposed method has the ability to rate the overall bridge condition and decide suitable remediation. © 2017 Inderscience Enterprises Ltd.
Jayathilake H.M.,General Sir John Kotelawala Defence University |
Vidanagama D.U.,General Sir John Kotelawala Defence University
16th International Conference on Advances in ICT for Emerging Regions, ICTer 2016 - Conference Proceedings | Year: 2016
The management of Sri Lankan school and club level cricket board faces the challenge of dealing with match statistics in match analysis using manual methods. The analysis of previous cricket matches is time consuming and messing up due to lack of technology. The aim of this research is to upgrade the Sri Lankan school cricket with the blend of information technology to solve the existing problems. The proposed solution is focusing on implementing a web based system using open source technologies to solve the issues regarding with match analysis. Also a Genetic Algorithm based advanced team selection model is presented in line with the web solution. Mainly the inputs to the system are gathered through the online scorecard while the outputs of the system are in the form of graphical representation. The web based solution is suggested to use in school cricket of Sri Lanka in order to witness the cost effective technological advantages in their decision making activities. © 2016 IEEE.
Nadugala M.N.,General Sir John Kotelawala Defence University |
Jeewandara C.,University of Sri Jayawardanapura |
Malavige G.N.,University of Sri Jayawardanapura |
Premaratne P.H.,General Sir John Kotelawala Defence University |
Goonasekara C.L.,General Sir John Kotelawala Defence University
PLoS ONE | Year: 2017
This study aims to characterize the antigenicity of the Capsid (C) protein and the human antibody responses to C protein from the four dengue virus (DENV) serotypes. Parker hydrophilicity prediction, Emini surface accessibility prediction and Karplus & Schulz flexibility predictions were used to bioinformatically characterize antigenicity. The human antibody response to C protein was assessed by ELISA using immune sera and an array of overlapping DENV2 C peptides. DENV2 C protein peptides P1 (located on C protein at 2-18 a.a), P11 (79-95 a.a) and P12 (86-101 a.a) were recognized by most individuals exposed to infections with only one of the 4 DENV serotypes as well as people exposed to infections with two serotypes. These conserved peptide epitopes are located on the amino (1-40 a.a) and carboxy (70-100 a.a) terminal regions of C protein, which were predicted to be antigenic using different bioinformatic tools. DENV2 C peptide P6 (39-56 a.a) was recognized by all individuals exposed to DENV2 infections, some individuals exposed to DENV4 infections and none of the individuals exposed to DENV1 or 3 infections. Thus, unlike C peptides P1, P11 and P12, which contain epitopes, recognized by DENV serotype cross-reactive antibodies, DENV2 peptide P6 contains an epitope that is preferentially recognized by antibodies in people exposed to this serotype compared to other serotypes. We discuss our results in the context of the known structure of C protein and recent work on the human B-cell response to DENV infection. © 2017 Nadugala et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Senanayake N.P.,General Sir John Kotelawala Defence University |
Chandrasiri N.S.,Colombo South Teaching Hospital
Sri Lanka Journalof Child Health | Year: 2015
Introduction: Urinary tract infections (UTIs) are an important cause of morbidity and mortality in children. Objective: To determine the common bacterial pathogens causing UTI in children less than 12 years old and their antimicrobial susceptibility patterns at the Colombo South Teaching Hospital, Sri Lanka. Method: A prospective study was done by analyzing records of urine samples received at the Department of Microbiology, Colombo South Teaching Hospital, from 1st May 2011 to 30th April 2012. Urine samples were inoculated on Cystine Lactose Electrolyte Deficient agar, according to standard operating procedures. The isolates were initially identified by Gram staining and colony characteristics. Gram positive organisms were further identified by catalase, coagulase and bile-aesculin tests. Lactose fermentation or non-lactose fermentation (NLF) of Gram negative organisms was recorded. The NLF isolates were further identified by oxidase, urease and Kleigler Iron Agar tests. Antibiotic susceptibility tests were carried out using the Stokes method. Results: A total of 2620 urine samples was analyzed. Of the 426 (16.3%) pure growths, Gram negative isolates of bacteriuria (>105 colony forming units/ml of urine) and Gram positive isolates of bacteriuria (>104 colony forming units/ml of urine) were found in 264 (62%) and 56 (13.1%) patients respectively. The female: male ratio of the total positive samples was 2.1:1. LF and NLF Coliforms (excluding Proteus, Providencia, and Morganella spp.) were isolated in 142 (33.3%) and 68 (16%) samples respectively. Proteus spp. were isolated in 43 (10.1%) samples 38 (88.4%) of which were identified in males. The sensitivity of LF Coliforms to nitrofurantoin, cephalexin and ampicillin was 83.9%, 57.4% and 11.3% respectively. The sensitivity of NLF Coliforms to nitrofurantoin, cephalexin and ampicillin was 85.3%, 36.8% and 7.4% respectively. Conclusions: Enterobacteriaceae were the predominant pathogens causing UTI in our population and showed high resistance against ampicillin and cephalexin. Proteus infections were predominant in males.
Jayarathne D.G.N.,General Sir John Kotelawala Defence University |
Jayananda M.K.,University of Colombo
2014 7th International Conference on Information and Automation for Sustainability: "Sharpening the Future with Sustainable Technology", ICIAfS 2014 | Year: 2014
In this paper the development of a Field programmable Gate Array (FPGA) based general purpose computer to Controller Area Network (CAN) store and forward buffer is being discussed. This buffer will read from the incoming data from the computer as bytes and collect and combine them to form the CAN frame and post it to the CAN network for transmission. In the process of development, CAN message frame architecture, voltage levels and bit coding principles were studied extensively. For the experiments and implementation of the designed buffer a developer board with Xilinx Spartan 3E FPGA which has 1920 Configurable Logic Blocks (CLB) was used. Computer to FPGA communications is carried out using RS-232 serial communications. 136 bit long CAN frame is built on the computer and separated to 17 bytes and forwarded to the FPGA. The FPGA assembles it and posts the frame to the network. In this implementation, from the available total, 315 flip flops and 569 look up tables (LUT) were used. From these 443 were used as logic, 126 were used as route through and 1 was used as a shift register. Since the usage of the RS-232 protocol a communication bottleneck makes rise to a delay of 14.1667 ms per frame sent from computer to the FPGA. This delay can be reduced by using Universal Serial Bus (USB) protocols to communicate with the computer. Even though this implementation is for the low speed fault tolerant CAN, speeds can be customized to suit the requirement by varying the frequency of clock ticks, given that the hardware supports such frequencies. As further research this store and forward buffer can be improved to receive acknowledgments from other nodes of the network. © 2014 IEEE.
Fernando S.,General Sir John Kotelawala Defence University |
Wijesiriwardana R.,General Electric
9th International Conference on Industrial and Information Systems, ICIIS 2014 | Year: 2015
Uncompressed multimedia (graphics, audio and video) data require significant storage capacity and transmission bandwidth. Despite rapid development in mass-storage density, processor speeds, and performance of digital communication systems, demand for data storage capacity and data-transmission bandwidth outperform the capabilities of available multimedia technologies. The recent developments of multimedia based applications have contributed not only for efficient ways of encoding signals but also in compression of signals. Therefore, the theory of data compression becomes more and more significant for reducing the data redundancy to save more hardware space and transmission bandwidth. In computer science and more specifically in information theory, data compression is the process of encoding information using fewer bits or other information bearing units rather than an un-encoded representation. Data compression is useful because, it cuts down expensive resources such as hard disk space or transmission bandwidth. Image compression is an application of data compression on digital images, as it reduces the computational time and consequently the cost of image storage and transmission. The fundamental concept about image compression is to remove redundant and unimportant data, and at the same time keeping the compressed image with acceptable quality. An important concept in image compression is to select the proper compression technique based on different categories of images, otherwise the data storage methods or transmission bandwidth will not be utilized in an optimized way. The objective of this research is to find an optimized image compression technique based on different categories of images. These categories are defined as high contrast, highly textured, images with a complex background with multiple objects and images with clear cut background with an object. The optimized method for compression was predicted based on the entropy of the image. The first compression technique employed was based on the wavelet transform, where the testing was carried out using three types of wavelet functions namely: Haar, Morlet and Meyer. The second compression method called seam carving, is an image resizing algorithm where, the image can be downscaled or up scaled by removing the seams or establishing number of seams. The results show the effectiveness of the proposed methodology. MatLab™ was used for the comparisons. © 2014 IEEE.
Senaratne B.,General Sir John Kotelawala Defence University
Maritime Affairs | Year: 2016
The Indian Ocean covers 20% of the Earth and is ranked as the third largest water body in the world. It has various matters related to maritime affairs which have to be resolved and policies that need to be implemented to ensure maritime safety and security of the littoral countries. In this context, the formulation of a common maritime policy will be beneficial in safeguarding not only the states but also the natural resources in the region. This paper demonstrates that the use of public diplomacy is a beneficial tool in formulating a common maritime policy. It also argues that this tool is useful in influencing public and governments in cooperating towards formulating and implementing policies and strategies that are important for maritime safety and security in the Indian Ocean Region. © 2016 National Maritime Foundation.
Fernando W.C.D.K.,General Sir John Kotelawala Defence University |
Wickramasuriya S.S.,University of Moratuwa
International Journal of Climatology | Year: 2011
Probable maximum precipitation (PMP) is widely used as an input in rainfall-runoff modelling to estimate probable maximum flood (PMF), which is required for the design of spillways of large dams. In relation to dam safety studies at 32 dam sites, an analysis was done of extreme rainfalls in Sri Lanka, which is influenced by the Asian monsoon system and cyclonic effects. Accordingly, the Hershfield's statistical method, which is one of the recommended procedures of the World Meteorological Organization (WMO), was used for estimating PMP. It is also a technique that can be readily used in design office practice. However, it is of significant value and scientific interest to explore what the outcome would have been if the physically based hydro-meteorological procedure had been adopted. For this purpose, long series of annual maximum daily rainfall data from seven stations were analysed. The research shows that the maximum moisture and corresponding wind run or the use of maximum moisture alone are two scenarios, which yield results compatible with the statistical PMP. Although globally there is a tendency to exclude wind maximization, this does not automatically apply to a country like Sri Lanka, which experiences cyclonic rainfall and special attention should be paid to precipitation efficiency. These results are further confirmed by a frequency analysis based on the generalized extreme value (GEV) distribution. An approximate value of PMP could be in the order of 2.0-3.0 times the maximum observed daily rainfall. However, this aspect needs further investigation when observed maxima are near PMP storms. © 2010 Royal Meteorological Society.
Wedasinghe N.,General Sir John Kotelawala Defence University |
Wicramaarchchi R.,University of Kalaniya
1st International Conference on Electrical Engineering and Information and Communication Technology, ICEEICT 2014 | Year: 2014
According to the statistics of the World Health Organization 15 percent of the world population lives with some kind of a disability. This statistic further indicates that 10 percent of the Sri Lankan total population also has some kind of disability. Sri Lanka suffered three decades of civil war. As a result no of disabled people gradually increased. Most of the civilians disadvantage of getting benefits of ICT during that period. As a result the war ending in 2009, the government strategies for the future were directed more on the Development of the country. Sri Lanka ICT literacy rate was increases 8% in 2005. It was increases up to 40 % in 2013. Government focuses to be 75 percent by the year 2015. The motivation behind this research is to overcome disability digital divide in Sri Lanka and facilitate more opportunities for them to enjoy in the digital world. The objective of this study is to propose a Web, Mobile and Computer related ICT model to bridge the disability digital divide gap in Sri Lanka and improve the quality of life of the differently abled community in Sri Lanka. This study involved Literature survey, and many different data gathering techniques mainly group discussions, interviews and site visiting more than 107 samples were interviewed to propose the model. Sri Lankan Participants for this study were inclusive of informal interviews with different communities, different disabled categories and different geographical locations. Study findings were indicated that most of the Sri Lankan differently abled community is not aware and not benefited from globally available modern technologies available for this community. This model is basically proposed based on the initial study has done in phase one to eliminate Disability Digital Divide in Sri Lanka and this paper is a revised model proposed by the same author. This new model includes guidelines to eliminate categories under disability digital divide in Web services, Mobile devises, Computer devises. This paper further proposes to consider the areas in ICT to be considered and the responsible authorities and stakeholders who need to take the initiation to eliminate the disability digital divide in Sri Lanka. © 2014 IEEE.
Ye C.,Wayne State University |
Bandara W.M.M.S.,Wayne State University |
Bandara W.M.M.S.,General Sir John Kotelawala Defence University |
Greenberg M.L.,Wayne State University
Journal of Biological Chemistry | Year: 2013
Background: Regulation of inositol metabolism is crucial for cellular functions. Results: Inositol pyrophosphate-deficient cells exhibit defective inositol biosynthesis. Protein levels of the inositol pyrophosphate biosynthetic enzyme Kcs1 are dynamically altered in response to inositol. Conclusion: INO1 transcription and inositol biosynthesis are regulated by modulation of inositol pyrophosphate synthesis. Significance: Inositol pyrophosphates are novel regulators of biosynthesis of inositol and inositol phospholipids. Although inositol pyrophosphates have diverse roles in phosphate signaling and other important cellular processes, little is known about their functions in the biosynthesis of inositol and phospholipids. Here, we show that KCS1, which encodes an inositol pyrophosphate kinase, is a regulator of inositol metabolism. Deletion of KCS1, which blocks synthesis of inositol pyrophosphates on the 5-hydroxyl of the inositol ring, causes inositol auxotrophy and decreased intracellular inositol and phosphatidylinositol. These defects are caused by a profound decrease in transcription of INO1, which encodes myo-inositol-3- phosphate synthase. Expression of genes that function in glycolysis, transcription, and protein processing is not affected in kcs1Δ. Deletion of OPI1, the INO1 transcription repressor, does not fully rescue INO1 expression in kcs1Δ. Both the inositol pyrophosphate kinase and the basic leucine zipper domains of KCS1 are required for INO1 expression. Kcs1 is regulated in response to inositol, as Kcs1 protein levels are increased in response to inositol depletion. The Kcs1-catalyzed production of inositol pyrophosphates from inositol pentakisphosphate but not inositol hexakisphosphate is indispensable for optimal INO1 transcription. We conclude that INO1 transcription is fine-tuned by the synthesis of inositol pyrophosphates, and we propose a model in which modulation of Kcs1 controls INO1 transcription by regulating synthesis of inositol pyrophosphates. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.