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Lv J.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital | Chen Q.-X.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital | Liu L.-J.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital
Journal of Clinical Neurology (China) | Year: 2013

Objective: To explore the clinicopathological features of dysembryoplastic neuroepithelial tumor (DNT). Methods: The clinical data of one DNT patient was analyzed retrospectively. Results: This case was young male. The frist symptoms were episodes of limb spasm and conscious disturbance. MRI showed the lobus temporalis with low signal on T1WI and high signal on T2 WI without enhancement and mass effect. The lesions consisted of multinodular specific glioneuronal elements and microcystic finely background mucinous matrix. The tumor composed of neurons, oligodendrocyte-like cells and ast rocytes, and accompanied with cortical dysplasia. Immunohistochemical showed neuronal nuclear antigen, synaptophysin and neuron specific enolase in the neurons and some oligodendrocytelike cells (OLC) were positivity. The S-100 protein in OLC was positive. The staining of glial fibrillary acidic protein in the astrocytes was positive. The positive rate of Ki-67 nuclear was 1 % in neoplastic cell. Conclusions: DNT is mainly happened in children and the youth. A part of the patients have chronic epilepsy history. The histological characters of DNT are the neuroglia and neuronal element. Source


Zhou J.-G.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital | Qiu Y.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital | Cen B.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital | Jiang Y.,General Hospital of the Yangtze River Shipping Wuhan Brain Hospital
Chinese Journal of Tissue Engineering Research | Year: 2014

Background: Subcutaneous effusion often occurs after digital shaping titanium mesh cranioplasty, and affects therapeutic effects. Objective: To explore the causes and corresponding prevention measures of subcutaneous effusion after digital shaping titanium mesh cranioplasty. Methods: We retrospectively analyzed the clinical data and treatment methods of 19 cases of subcutaneous effusion after digital shaping titanium mesh cranioplasty, summarized the postoperative complications and explored the effective methods for prevention and treatment of subcutaneous effusion. Results and Conclusion: After active treatment, five cases of dural breakage, four cases of foreign body stimulation, three cases of getting out of bed early, three cases of early extubation, three cases of long-time operation repair, and one case of excessive use of electric knife were all cured. Dural breakage and foreign body stimulation is considered as the main causes of postoperative effusion. Patients with subcutaneous effusion were given releasing elastic bandage, aspiration, and strict bed rest. After these active treatments, patients were all cured. Subcutaneous effusion may result from single or mixed factors. The above-mentioned causes are only a part. Non-central suspension, incomplete hemostasis, and preoperative excessive collapse of the bone window are all reported to be the reasons for the occurrence of subcutaneous effusion. Source

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