Lárisa, Greece
Lárisa, Greece

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Gerasimou-Angelidi S.,General Hospital of Larissa | Myrianthefs P.,National and Kapodistrian University of Athens | Chovas A.,General Hospital of Larissa | Baltopoulos G.,National and Kapodistrian University of Athens | Komnos A.,General Hospital of Larissa
Journal of Nursing Management | Year: 2014

Aim: To study family satisfaction with care in an Intensive Care Unit (ICU) and its association with nursing workload estimated by the Nursing Activities Score (NAS). Background: Few previous studies have investigated the association between workload in ICUs and family satisfaction. Methods: Family Satisfaction ICU 24 (FS ICU-24) questionnaires were distributed to 161 family members (106 respondents). Questionnaires' score, NAS measurements and Simplified Acute Physiology Score II (SAPS-II) data were analysed. Results: The mean total level of family satisfaction was equal to 80.72% (±9.59). Family members were more satisfied with the level of care compared with decision making. NAS values revealed a shortage of nurses in the morning shift. Moreover, there was a statistically significant positive correlation between NAS and total satisfaction after adjusting for age, length of stay and SAPS-II. Conclusions: Improvements in clinical practice require the measurement of care quality which particularly includes family satisfaction. Our results indicated that family members were less satisfied with decision making. Implications for nursing management: Nurse managers should plan for the successful involvement of family members in the decision-making process. Higher levels of nurse staffing might improve the care provided. © 2013 John Wiley & Sons Ltd.


Korres S.,National and Kapodistrian University of Athens | Riga M.,Democritus University of Thrace | Sandris V.,General Hospital of Larissa | Danielides V.,Democritus University of Thrace | Sismanis A.,National and Kapodistrian University of Athens
International Journal of Audiology | Year: 2010

Benign paroxysmal positional vertigo (BPPV) of the anterior semicircular canal (ASC) is an uncommon disorder currently diagnosed with the Dix-Hallpike (D-H) examination. According to the literature, nystagmus and vertigo may be more pronounced when the affected ear is either up or down. In some patients, both right and left D-H tests can trigger nystagmus with the same direction. The proposed treatment options with the addition of a different manoeuvre applied by the authors of the present study in cases of ASC lithiasis, seem to present a respective variety regarding the position of the affected ASC during the procedure of canalith repositioning. The aim of this study is to analyse the mechanisms underlying both the proposed treatment options and the clinical findings in the D-H examination. The results of this analysis stimulate further investigation, since they probably imply that repositioning manoeuvres might vary in their effectiveness when applied to different clinical subgroups of ASC BPPV. © 2010 British Society of Audiology, International.


Avramidis K.,General Hospital of Larissa | Karachalios T.,University General Hospital of Larissa | Popotonasios K.,General Hospital of Larissa | Sacorafas D.,General Hospital of Larissa | And 2 more authors.
Orthopedics | Year: 2011

Patients with knee osteoarthritis present with reduced quadriceps muscle strength, which is partially responsible for impaired function and disability. Although total knee replacement (TKR) is an effective surgical procedure, residual muscle weakness is not usually addressed and may persist for years postoperatively. This article reports the results of a prospective, randomized, controlled trial evaluating the effect of electric muscle stimulation of the vastus medialis on the speed and effort of walking, quality of life, and knee performance in patients undergoing TKR. Seventy patients who underwent TKR were randomly divided into 2 groups. Patients in group A received electric muscle stimulation and standard physiotherapy for 6 weeks, while patients in group B received physiotherapy only. All patients were assessed with both subjective and objective clinical scales preoperatively and at 6, 12, and 52 weeks postoperatively. Patients in group A demonstrated a statistically significant increase in walking speed, Oxford Knee Score, and American Knee Society function score compared to those in group B at 6 weeks (P=.003, .001, and .001, respectively) and at 12 weeks (all P=.001). A statistically significant increase in the SF-36 physical component summary score was observed at 6, 12, and 52 weeks (all P=.001). Three patients found the sensation of the electrical stimulation uncomfortable and abandoned its use. No skin reactions and surgical site infections were observed. Electrical stimulation of the vastus medialis muscle in addition to conventional physiotherapy improves functional recovery and early rehabilitation after TKR.


Batzakakis D.,General Hospital of Larissa | Stathas T.,University of Patras | Mastronikolis N.,University of Patras | Kourousis C.,University of Patras | And 2 more authors.
American Journal of Rhinology and Allergy | Year: 2014

Background: Nasal polyposis is a chronic inflammation of nasal and paranasal sinuses in the pathogenesis of which adhesion molecules may have a significant role. This study investigates the possible role of certain adhesion molecules, mucins, and oncogenes in nasal polyposis recurrence. Methods: A sample study of 21 individuals (17 men and 4 women) aged 47.44 ± 15.10 years with nasal polyposis who had undergone nasal surgery twice was used. Twenty-one individuals aged 46.9 ± 12.8 years suffering from nasal polyposis who had undergone surgery only once in the same period were used as a control sample. Results: Statistically significant differences between the two groups were observed regarding epithelial membrane antigen (EMA/mucin 1) of stromal cells (p < 0.001) and CD86 stromal expression (p = 0.009). No patient of the control group exhibited high (++) CD86 stromal expression, whereas six patients of the resurgery group did so. When EMA and CD86 were included in a logistic regression model, stromal EMA was found to be positively related to recurrence. Conclusion: Adhesion molecules may relate to nasal polyp prognosis and recurrence rates. Copyright © 2014, OceanSide Publications, Inc.


Kolovos S.,General Hospital of Larissa | Tsiotas D.,University of Thessaly
European Journal of Orthopaedic Surgery and Traumatology | Year: 2016

Introduction: CTS, the most common nerve entrapment syndrome of the upper limb, is being diagnosed by clinical criteria, in most cases supported by the electrodiagnosis method, which appears limits regarding its sensitivity and specificity and suggests an intervening and expensive technique. The purpose of this study was to contribute to establishing U/S examination as a method with at least of the same accuracy with electrodiagnosis. Material and method: A sample of 60 healthy individuals and 30 patients suffering from CTS was scanned. The diagnosis was conducted by both clinical and electrodiagnostic criteria, or by clinical criteria supported by postsurgical outcome. Method: In order to improve the accuracy of measurements, the anteroposterior to transverse diameter of the median nerve inside the canal and in its entrance was scanned and compared, by sonography. The examination conducted three times for each dimension, and the mean value per individual was calculated. Results: The mean ratios for the 60 healthy wrists was found to range within the interval 0.49–0.88 (presenting a mean value of 0.66), and the corresponding for the 30 suffering from CTS wrists was within the interval 1.12–1.59 (with a mean value of 1.39). Conclusion: The statistical analysis of the examination results clearly demonstrates that the interval of ratios over the value 1.07 can be considered completely safe to diagnose that someone is suffering from CTS. In correspondence, a U/S measurement of ratios in the area up to 0.79 is completely safe to opine that this wrist refers to a healthy individual. The intermediate range of ratios 0.79–1.0 suggests a grey zone, which, by the rational of this study, does not include discrete CTS or healthy cases. This “gap” may describe subclinical or mild cases of CTS which were not been taken under consideration and for which there is no rational to interfere surgically. In the everyday’s practice clinical point of view, the grey zone cases are considered healthy. © 2015, Springer-Verlag France.


Vageli D.P.,University of Thessaly | Doukas S.G.,University of Thessaly | Markou A.,General Hospital of Larissa
Pediatric Blood and Cancer | Year: 2013

Mismatch DNA repair (MMR) mRNA expression analysis was performed on a biopsy of oral mucosa melanin pigmentation lesion, a hamartomatous polyp and peripheral blood derived from a 12-year-old child with Peutz-Jeghers Syndrome (PJS). We present a deficient MMR system, in a PJS patient, which demonstrated low mRNA levels of hMSH6 and hPMS2 and an increasing MMR deficiency from the non-dysplastic lesion to hamartomatous polyp of PJS with a high risk of cancer. Pediatr Blood Cancer 2013;60:E116-E117. © 2013 Wiley Periodicals, Inc.


Makris D.,University Hospital of Larissa | Manoulakas E.,University Hospital of Larissa | Komnos A.,General Hospital of Larissa | Papakrivou E.,University Hospital of Larissa | And 5 more authors.
Critical Care Medicine | Year: 2011

Objective: To investigate whether the use of pravastatin reduces the frequency of ventilator-associated pneumonia and whether it is related to favorable outcomes in critical care patients. Design: Two-center, two-arm, randomized, open-label, controlled trial. Setting: University Hospital and General Hospital of Larissa, Greece. Patients: Consecutive patients were recruited from the intensive care units of the two hospitals. Patient inclusion criteria included mechanical ventilation and intensive care unit stay of >48 hrs. Interventions: The two arms consisted of treatment plus oral pravastatin sodium (40 mg) (n = 71 patients, pravastatin group) and treatment without pravastatin (n = 81 patients, control group). Treatment was started after randomization and ended 30 days later. Measurements and Main Results: Ventilator-associated pneumonia frequency and intensive care unit mortality at 30 days and at the end of intensive care unit stay were measured. Adverse events related to statin treatment in the intensive care unit were documented. Sixteen patients (22.5%) in the pravastatin group and 28 (34.5%) in the control group (p = .11) presented pneumonia during the 30-day treatment period in the intensive care unit. There was an indication for increased probability of being free from ventilator-associated pneumonia during the 30-day treatment period in the pravastatin group compared to the control group (p = .06) and significantly increased probability during the whole intensive care unit period of stay (p = .04) in the pravastatin group compared to the control group in the subgroup of patients with Acute Physiology and Chronic Health Evaluation scores of ≥15. Six patients (8.45%) in the pravastatin group and 16 (19.85%) in the control group died during the 30-day treatment period (p = .06), whereas 10 (14.1%) patients in the pravastatin group and 24 (29.1%) patients in the control group died during the whole period of intensive care unit stay (p = .03). Pravastatin group patients with Acute Physiology and Chronic Health Evaluation scores of ≥15 had significantly increased probability of survival compared to controls during the 30-day treatment period (p = .04). Creatine kinase and hepatic function enzyme levels during the whole study period were not significantly different between the pravastatin group and control group. Conclusion: This study provides evidence that pravastatin may favorably affect the outcome of critical care patients. © 2011 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins.


Koutsiaris A.G.,Technological Educational Institute of Larissa | Tachmitzi S.V.,General Hospital of Larissa | Batis N.,Technological Educational Institute of Larissa
Microvascular Research | Year: 2013

Blood volume flow (Q), wall shear rate (WSR) and wall shear stress (WSS) were quantified, for the first time, in the conjunctival pre-capillary arterioles of normal human volunteers with diameters (D) between 6 and 12μm. The variation of the blood velocity throughout the cardiac cycle was taken into account using high speed video microcinematography. The dual effect of arteriolar diameter, firstly on the WSR and secondly on the dynamic viscosity of blood, was taken into account in the estimation of WSS. The average Q, WSR and WSS, throughout the cardiac cycle ranged from 13 to 202 pl/s, 587 to 3515s-1 and 1.7 to 21.1N/m2 respectively. The best fit power law equations, giving the increase of Q and the decrease of WSR and WSS with diameter, are presented for the systolic and diastolic phase as well as for the averages throughout the cardiac cycle. According to the WSS best fit equation, the average WSS decreases from 10.5N/m2 at D=6μm down to 2.1N/m2 at D=12μm. © 2012 Elsevier Inc.


Koufakis T.,General Hospital of Larissa | Gabranis I.,General Hospital of Larissa
Pan African Medical Journal | Year: 2014

Erythema nodosum is a panniculitis which may have various causes, such as drugs, infections, sarcoidosis, inflammatory bowel disease, tuberculosis or can be idiopathic. We here report a case of a womandiagnosed with pulmonary tuberculosis whose first symptom was erythema nodosum. A thorough clinical and laboratory investigation of the patient presenting with erythema nodosum is always required, in order to assess a possible systemic, underlying condition. © Theocharis Koufakis et al.


Hantes M.E.,University Hospital of Larissa | Venouziou A.,University Hospital of Larissa | Bargiotas K.A.,University Hospital of Larissa | Metafratzi Z.,General Hospital of Larissa | And 2 more authors.
Arthroscopy - Journal of Arthroscopic and Related Surgery | Year: 2010

Purpose: The purpose of this study was to determine quantitatively whether the Latarjet procedure (coracoid transfer to the glenoid) is sufficient to restore a significant defect area of the glenoid. Methods: Fourteen cadaveric shoulders were used (mean age, 76 years; range, 72 to 87 years). An anteroinferior glenoid defect was created and then the coracoid osteotomized to its angle and transferred to the defect. A 3-dimensional computed tomography scan was used to calculate the surface area of (1) the intact glenoid, (2) the osteotomized glenoid, and (3) the reconstructed glenoid. Results: The mean area of the intact inferior glenoid was 734 ± 89 mm 2. After creation of the defect, the surface area of the glenoid was reduced significantly to 523 ± 55 mm 2 (P = .011). The mean defect area was 28.7% ± 6% of the intact glenoid. After coracoid transfer, the mean surface area of the reconstructed glenoid was 708 ± 71 mm 2 but it was not significantly smaller than that of the intact glenoid (P = .274). The mean surface area of the coracoid that was used to repair the defect was 198 ± 34 mm 2, or 27% ± 5% of the intact glenoid. Conclusions: In our cadaveric model, a mean 29% defect size of the inferior glenoid was restored to normal after coracoid transfer by use of the Latarjet procedure. Clinical Relevance: In the clinical scenario, the existence of a glenoid bone defect of more than 25% to 30% is very rare in patients with anterior shoulder instability. Therefore, when clinically indicated, large bony defects of the anterior glenoid can be adequately treated by the Latarjet procedure. © 2010 Arthroscopy Association of North America.

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