General Hospital Evagelismos

Greece

General Hospital Evagelismos

Greece
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Papachristou M.,General Hospital Evagelismos | Georgiou A.,General Hospital Laiko | Kolintou A.,General Hospital Laiko | Kyriaki D.,General Hospital Laiko
Pharmakeftiki | Year: 2012

Zevalin therapy is a new treatment for NHL which demands a different preparation procedure and administration. The Nuclear Medicine Department of General Hospital "Laiko" had a series of therapies, 10 of those were "multiple" labeling preparation procedures. The preparation of the radiopharmaceutical was based on the labeling of rituximab with [90Y]Cl3 (Kit) and for the quality control, ITL-Chromatography was used. The radiolabelings were 1 to 3 per day. The process is reproducible and provides a consistent quality product for patient administration. "Slow-push" injection (i.v) is the way to administer the drug. The whole procedure is considered to be complexed for the Nuclear Medicine Departments of Hellenic Hospitals.


Kalogeropoulos I.,General Hospital Evagelismos | Lazarioti F.,General Hospital Evagelismos | Skabardoni M.,General Hospital Evagelismos | Skouras I.,General Hospital Evagelismos | Piperopoulos P.,General Hospital Evagelismos
Cancer Therapy | Year: 2010

The purpose of our study is to present the commonest radiological findings of gastric lymphomas in double contrast barium meal in correlation with Helicobacter pylori infection and pathological findings. Gastric MALT lymphoma has been diagnosed in 15 patients (9 men and 6 women) at our institution during the last two years (2007-2008). Histology specimens were taken by biopsy during endoscopy or surgery. Ten of them have undergone double contrast barium meal examination. The clinical symptomatology included epigastric pain (80%), anorexia (14%) and gastrointestinal hemorrhage (7%). The barium meal contrast examination findings included ulcers (shallow or deep) mass with or without ulcer, mucosal fold thickening, nodularity of the mucosa, enlarged areae gastricae as in gastritis. The results of the biopsies showed that 13 patients had lesions in the fundus of the stomach and 2 of them in the duodenal bulb. Eleven patients proved to have low grade lymphoma and 4 had high grade lymphoma. Eleven out of fifteen patients were infected by Helicobacter pylori and 10 of them had multiple MALT lesions, fact that reveals a strong correlation between MALT lymphoma and H. Pylori infection. Considering the fact that low grade MALT lymphomas have a very good prognosis if diagnosed in time, revealing radiological manifestations at earlier stages is very important.

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