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Benbouzid H.,General Direction of Scientific Research and Technological Development | Berrebbah H.,General Direction of Scientific Research and Technological Development | Berredjem M.,Annaba University | Djebar M.-R.,General Direction of Scientific Research and Technological Development
Toxicological and Environmental Chemistry | Year: 2012

The toxicological impacts of the increasing number of synthetic compounds present in the aquatic environment are assessed predominantly in laboratory studies where test organisms are exposed to a range of concentrations of single compounds. Protozoan cells are often used as bioindicators for the presence of xenobiotic compounds. In this article, we describe the inhibitory effect of a synthetic phosphoramidate derivative at different concentrations (40, 60, and 80 μmol L -1) on Paramecium sp., affecting its growth (proliferation) in concentration-dependent manner, as well as the generation time and response percentage. The LC 50 value determined for these protozoa was estimated at 60 μmol L -1 on 24 h of exposure. The respiratory metabolism of protozoan is perturbed at three concentrations, noting that the oxygen consumption was significantly increased at high concentrations after 18 h of exposure. In addition, the data can be used as reference values in further testing with other pesticides. © 2012 Taylor and Francis Group, LLC.


Ouarna S.,Annaba University | Houria B.,General Direction of Scientific Research and Technological Development | Ktir H.,Annaba University | Amira A.,Annaba University | And 2 more authors.
Rasayan Journal of Chemistry | Year: 2012

A new series of substituted oxazolidin-2-ones containing chloroacetyl and phosphonate groups have been synthesized and their in vitro cytoxicity activities were evaluated against Paramecium sp at different parameters. Their synthesis were easily carried out starting from available oxazolidin-2-ones by chloroacetylation reaction following by introduction of phosphonate group using P(OEt)3 via Arbuzov reaction. Toxicological impact of these synthetic compounds showed promising results. © 2012 RASAYAN. All rights reserved.


Hicham S.,University MerbahOuargla | Abdelkader T.,General Direction of Scientific Research and Technological Development | Amina Y.,University MerbahOuargla | Didi O.E.M.,University MerbahOuargla
Energy Procedia | Year: 2015

Exploration anddevelopment of newenergy sources havebeen undertakenincludingbiomassenergyspecificallybiogas. Thisform of renewableenergywidelyavailable, inexpensiveand non-pollutingisused to supplementthenon-renewablefossil fuels. Therecovery of organicwasteandsludgemainlyatreatment plantwastewaterforbiogas productioncouldbeseen asa cost, decentralized and ecologicalproblemsthroughtheenergeticautonomyandsustainable agricultural developmentrural areas. Very little work in Algeria and elsewhere have been done on the microbiology of the different stages of the digestive process. Our goal is to make a microbiological study of the anaerobic digestion of sludge from the purifying plant wastewater from the city of Touggourt which is south east of Algeria © 2015 The Authors. Published by Elsevier Ltd.


Boufas W.,Annaba University | Dupont N.,University of Paris 13 | Berredjem M.,Annaba University | Berrezag K.,Annaba University | And 3 more authors.
Journal of Molecular Structure | Year: 2014

A series of substituted sulfonamide derivatives were synthesized from chlorosulfonyl isocyanate (CSI) in tree steps (carbamoylation, sulfamoylation and deprotection). Antibacterial activity in vitro of some newly formed compounds investigated against clinical strains Gram-positive and Gram-negative: Escherichia coli and Staphylococcus aureus applying the method of dilution and minimal inhibition concentration (MIC) methods. These compounds have significant bacteriostatic activity with totalities of bacterial strains used. DFT calculations with B3LYP/6-31G(d) level have been used to analyze the electronic and geometric characteristics deduced for the stable structure of three compounds presenting conjugation between a nitrogen atom N through its lone pair and an aromatic ring next to it. The principal quantum chemical descriptors have been correlated with the antibacterial activity. © 2014 Elsevier B.V. All rights reserved.


Hessainia S.,Annaba University | Bouchareb F.,Annaba University | Cheloufi H.,Annaba University | Berredjem M.,Annaba University | And 3 more authors.
Rasayan Journal of Chemistry | Year: 2013

A series of modified acyclic sulfamides and cyclic sulfamides were synthesized efficiently, using sulfuryl chloride that is the suitable available reagent allowing the introduction a sulfamide moiety. The cyclosulfamides were prepared in two steps (duplication and cyclization) starting from a primary amines. These compounds were preliminarily tested for antibacterial activity against Gram-positive and Gram-negative bacteria. The synthesized compounds exhibited excellent antibacterial activity as compared to the standard sulfamide drug, especially against the clinical strains. © 2013 RASĀYAN. All rights reserved.

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