Gazi University is a public university primarily located in Ankara, Turkey.It was established in 1926 by Mustafa Kemal Atatürk as Gazi Teacher Training Institute. In 1982, it was reorganized by merging with the Bolu Academy of Engineering and Architecture, Ankara Academy of Economics and Commercial science, the Ankara College of Technical Careers, the Ankara Girls' College of Technical Careers, and the Ankara State Academy of Engineering and Architecture to become a large metropolitan university as part of the act which created the Board of Higher Education. Prior to 1982 when the Board of Higher Education Law came into effect, institutes of higher education in Turkey were organized under different structures as universities, academies, institutes, and schools. In 1992 faculties and vocational schools in Bolu became Abant Izzet Baysal University.Gazi University comprises 21 faculties, 4 schools, 11 vocational schools of higher education, 48 research centers and 7 graduate institutes. The student enrollment of Gazi University has reached approximately 77,000 in total of whom about 1,500 come from the Turkic states of Central Asia. Five thousand students are enrolled in graduate programmes. The total size of the teaching faculty exceeds 3,000 persons. Wikipedia.
News Article | May 10, 2017
Scientists in Ankara, Turkey say their evaluation of pleural mesothelioma patients who had either intensity-modulated radiotherapy or a more conventional approach suggests that IMRT may be the better option. Surviving Mesothelioma has just posted an article on the new research. Click here to read it now. The Gazi University study analyzed the cases of 12 mesothelioma patients who received one-side radiation for pleural mesothelioma in doses ranging from 1.8 Gy to 50.4 Gy. “Intensity-modulated radiation therapy was statistically superior in target coverage and dose homogeneity,” says Sukran Ulger, MD, a radiation oncologist and part of the medical faculty at Gazi University. According to the study in the journal Technology in Cancer Research and Treatment, with IMRT, mesothelioma tumors received a higher dose of cancer-killing radiation while the surrounding healthy lung tissue received less. “Given that radiotherapy is often part of the multi-modal treatment of pleural mesothelioma, this study may sway patients and families to seek out cancer centers where IMRT is an option,” says Alex Strauss, Managing Editor for Surviving Mesothelioma. For a better understanding of IMRT in mesothelioma treatment and all the details of the new study, see Targeted Radiotherapy for Pleural Mesothelioma, now available on the Surviving Mesothelioma website. Ulger, S, et al, “Intensity-Modulated Radiation Therapy Improves the Target Coverage Over 3-D Planning While Meeting Lung Tolerance Doses for All Patients With Malignant Pleural Mesothelioma”, June 2017, Technology in Cancer Research & Treatment, pp. 332-338, http://journals.sagepub.com/doi/abs/10.1177/1533034616678110 For more than a decade, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.
Gunlu G.,Gazi University
IEEE Transactions on Energy Conversion | Year: 2017
In battery packs, batteries need to be serially connected to obtain high voltage, connected in parallel to acquire high current, and the defected batteries need to be bypassed. In this study, dynamically reconfigurable, independent cellular switching circuits have been proposed in order to connect the batteries in desired configuration. Each cell comprises a battery, a serial switch, a bypass switch, a parallel switch, and triggering switches. The batteries within the pack can be connected in different configurations according to their operation mode such as all in serial, all in parallel, all bypassed, or hybrid (serial-parallel-bypass). The novel aspect of the proposed circuit is that only intracellular battery energy is utilized in order to trigger the switches that are controlled with a very simple circuit. Each cell is independent and completely modular. Moreover, a single mosfet is sufficient instead of two mosfets which is connected in serial in order to control the current. The complexity of the circuit has been reduced to three mosfets for each cell and its efficiency has been increased. The operation of the proposed circuit has been tested with a prototype that includes twelve batteries and its advantages have been confirmed. © 2016 IEEE.
Orhan I.E.,Gazi University
Current Pharmaceutical Design | Year: 2016
Monoamine oxidase (MAO, E.C. 188.8.131.52) is a flavin-adenine type of enzyme with two isoforms referred to MAO-A and MAO-B that function for oxidation of monoamines. While MAO-A inhibitors are effective as antidepressant and anxiolytic drugs (e.g. chlorgyline, moclobemide, and lazabemide), inhibitors of MAO-B (e.g. Ldeprenyl, pargyline, and rasagiline) are used against neurodegenerative diseases such as Parkinson’s and Alzheimer’s diseases. Considering the need for novel MAO inhibitors due to side effects of the current ones, natural products have become attractive targets for researchers. Up till now, many studies revealed strong MAO inhibitory activity of flavonoid, xanthone, alkaloid, and coumarin derivatives from herbal sources, which also become good models for the synthetic MAO inhibitors. For this purpose, the present review focuses on examples of in vitro and in vivo MAO-inhibiting natural compounds of plant origin from a wide variety of chemical classes isolated mainly between 2000 – 2015. © 2016 Bentham Science Publishers.
Haciomeroglu M.,Gazi University
Adaptive Behavior | Year: 2016
In this study have we focused on two aspects of multi-agent simulations. The first is based on a finding in recent years, which is that a standalone global path does not always provide adequate multi-agent navigation in crowded scenarios. A global planner that is aware of other agent configurations and thus finds clearer paths is required for optimal navigation. In real life, usually, an agent is only aware of the area close to it. In this study, by taking into account this limitation, we propose a state-machine-based global planner that monitors agents’ close domains and, if required, modifies the path for congestion prevention. The second aspect is the coordination of local and global planners. Multi-agent navigation systems require both local steering and global path planning. As a matter of fact, these two systems should work in coordination since the output of one influences the other. A steering technique cannot always guarantee smooth and collision-free navigation while tracking the global planner’s path. Therefore, we propose a system that detects and rebuilds coordination between local and global path planners. © 2015, The Author(s) 2015.
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: HEALTH-2011.4.2-1 | Award Amount: 7.78M | Year: 2011
Dobutamine and adrenaline are widely used as second line therapy for systemic hypotension in infants. Dopamine is currently the most widely used first line drug. In neonates, sustained hypotension may, and impaired organ perfusion will, cause brain injury and poor neurodevelopmental outcomes. All three catecholamines are currently used off-label and have different modes of action which may result in potentially harmful haemodynamic effects. No reliable safety or efficacy data exists for the use of these drugs in neonates or newborns. Furthermore, no uniform criteria exist to define hypotension and there is little evidence to support current intervention strategies, which vary widely. Recently, superior vena cava (SVC) flow has been proposed as a more reliable indicator of circulatory failure than low blood pressure and preliminary results suggest Dobutamine is the optimum therapeutic in such cases. NEO-CIRC proposes 1) a randomised placebo controlled trial to provide safety and efficacy data for Dobutamine as a first line inotrope for all gestational ages 2) to perform pre-clinical; pharmacokinetic; pharmacodynamic; metabolomic and pharmacogenomic studies 3) to develop improved biomarkers of hypotension 4) to develop and adapt a formulation of Dobutamine suitable for newborns with the aim to apply for a Paediatric Use Marketing Authorisation. The NEO-CIRC consortium includes international experts in neonatal medicine, pharmacology, pharmacogenomics, drug formulation and pre-clinical neonatal models and an experienced group of experienced multicentre clinical trials NICUs. Outcomes anticipated include improved biomarkers of organ perfusion; a new consensus definition of neonatal circulatory failure and answers to key clinical practice uncertainties, including variability of response to Dobutamine in common pathophysiologies seen in newborn infants impact on longer term developmental outcomes so important to the patients, families and wider society.
Turker A.R.,Gazi University
Separation and Purification Reviews | Year: 2012
This review presents the most recent applications of solid phase extraction for the separation, preconcentration and speciation of metals, metalloids, and organometals. The review focuses on solid phase, column treatments and on the applications of this technique to various samples. This review also intends to discuss some applications and limitations associated to solid phase extraction techniques due to the necessity on limited selectivity. Nevertheless, the solid phase extraction is still an efficient, sensitive and inexpensive technique to perform removal of metal ions from environmental samples, preconcentration of metal ions for analytical purposes and speciation of the metal and metalloids as shown by the variety of applications presented and discussed in this review. A literature survey of the last three years (2008-2010) offering a critical review of solid phase extraction for separation, preconcentration and speciation of metal ions from various sample matrices is provided. © 2012 Copyright Taylor and Francis Group, LLC.
Sevik S.,Gazi University
Energy Conversion and Management | Year: 2013
In this experimental study, a new type solar dryer has been designed and manufactured by using double-pass solar air collector, heat pump and photovoltaic unit. The performance of solar dryer has been tested for carrot drying. In drying system, double-pass solar air collector (DPSAC) has provided the system heat energy requirement for drying process. Constant drying air temperature has been provided with PID (proportional-integral-derivative) control. Carrot slices were dried from initial moisture content 7.76 g water/g dry matter (dry basis) to final moisture content 0.1 g water/g dry matter (dry basis) at 50 °C drying air temperature and variable air volume. Velocity of air has been changed depending upon air inlet temperature of drying cabinet. During the drying operation, the air velocity was measured 0.4-0.9 m/s. The thermal efficiency of the double-pass collector was calculated from 60% to 78% according to experimental results. Carrot slices were dried at 220 min by using double-pass solar air collector in solar-heat pump dryer. Consequently, system (solar-heat pump dryer) can be comfortably operated without the need to the heat pump under normal ambient air conditions.© 2013 Elsevier Ltd. All rights reserved.
Arikan F.,Gazi University
Expert Systems with Applications | Year: 2013
In today's severe competitive environment the selection of appropriate suppliers is a significantly important decision for effective supply chain management. Appropriate suppliers reduce purchasing costs, decrease production lead time, increase customer satisfaction and strengthen corporate competitiveness. In this study a multiple sourcing supplier selection problem is considered as a multi objective linear programming problem. Three objective functions are minimization of costs, maximization of quality and maximization of on-time delivery respectively. In order to solve the problem, a fuzzy mathematical model and a novel solution approach are proposed to satisfy the decision maker's aspirations for fuzzy goals. The proposed approach can be efficiently used to obtain non-dominated solutions. A numerical example is given to illustrate how the approach is utilized. © 2012 Elsevier Ltd. All rights reserved.
Cakir H.,Gazi University
Computers and Education | Year: 2013
Web 2.0 technologies allow average computer users to be able to publish on the Internet without having to know complex computer technical knowledge, which gives these technologies powerful potential to facilitate student engagement in various learning environments. However, a knowledge gap exists in the literature related to factors affecting student engagement with Web 2.0 technologies. The purpose of this study is to understand factors affecting student engagement in a pre-service teacher education program that uses blogs to expand in-class discussions about technology integration. First year pre-service teachers in a mathematics education department participated in the study. Data were collected with a survey that was developed to measure student engagement with blog use. Results show that student motivation, reasons to use blog in the course, and level of challenge perceived by the students affect students' engagement with blog use. Gender and technical ability of students do not impact students' engagement. As a result, blogs can be utilized to expand in-class discussions equally well for all students. © 2013 Elsevier Ltd. All rights reserved.
Ocak M.A.,Gazi University
Computers and Education | Year: 2011
This paper describes the findings of an exploratory, qualitative case study and examines problems and impediments faculty members encountered in blended learning environments in Turkish Higher Education system. A total of 117 faculty members from 4 universities responded to 8 interview questions. Findings were based on content analyses of interview transcripts. The results show that faculty members' problems with blended teaching resulted in the identification of three inductive categories: instructional processes, community concerns and technical issues. The eight themes emerged from these three categories include the following: (1) complexity of the instruction, (2) lack of planning and organization, (3) lack of effective communication, (4) need for more time, (5) lack of institutional support, (6) changing roles, (7) difficulty of adoption to new technologies and (8) lack of electronic means. This study indicates that teaching blended courses can be highly complex and have different teaching patterns, which, in turn, impacts successful implementation of the blended college courses. © 2010 Elsevier Ltd. All rights reserved.