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Qiu X.-H.,Gannan Medical University | Zhou L.-L.,Gannan Medical University | Yang Y.,Gannan Medical University | Wang X.-J.,Ganzhou Tumor Hospital
IFMBE Proceedings | Year: 2015

The finite element numerical model of the two microbubbles in the microvessel is built in our study. The model is solved by finite element analysis software. The pressure of observing point P (away from one of two microbubbles A 3 μm) is used to express the intensity of ultrasonic cavitation. The results show that the pressure on point P is higher than single microbubble case because of the aggravation of the cavitation effect, and with the increasing of the distance of two microbubbles, the effect of adjacent microbubble on point P decreases. These results lay the foundation of the research of the agent concentration effect on clinical diagnosis and treatment. © Springer International Publishing Switzerland 2015.


Zhang X.,Ganzhou Tumor Hospital
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery | Year: 2013

To evaluate the long-term efficacy of submandibular gland transfer for prevention of xerostomia after radiotherapy for nasopharyngeal carcinoma. Sixty-five cases of nasopharyngeal carcinoma patients were randomly divided into study group of 32 patients and control group of 33 patents. The submandibular gland was transferred to submental region on 32 cases with nasopharyngeal carcinoma before receiving conventional radiotherapy and a block was used to cover the submental region. Before radiotherapy, two groups of submandibular gland function was detected by imaging of the submandibular gland. At 60 months after radiotherapy, submandibular gland function was detected by 99mTc radionuclide scanning, the questionnaire about the degree of xerostomia was investigated respectively. Five-year survival rate was counted. After following up for 60 months, submandibular gland uptake and secretion function in the study group was significantly higher than that in the control group, there was significant difference between the two groups (P < 0.01) respectively. The incidence of moderate or severe xerostomia in the study group was significantly lower than that in the control group (15.4% vs 76.9%, P < 0.01). Five-year survival rate of the study group and control group was 81.3% and 78.8% respectively, there was no significant difference between the two groups (P > 0.05). The long-term efficacy of submandibular gland transfer for prevention of xerostomia after radiotherapy for nasopharyngeal carcinoma was well. It could improve the quality of life in nasopharyngeal carcinoma patients after radiotherapy, and did not affect the long-term efficacy of nasopharyngeal carcinoma.


Qiu X.,Gannan Medical University | Zhou Y.,Gannan Medical University | Peng Y.,Gannan Medical University | Zhou L.,Gannan Medical University | Wang X.,Ganzhou Tumor Hospital
IFMBE Proceedings | Year: 2013

The finite element numerical models of the microbubble with and without shell are built in our study. The calculation results indicate that the frequency response of the shell-microbubble is different from that of microbubble without shell. Furthermore, the frequency response of microbubble is closely related to the relevant parameters of the shell. The thickness and the Young's modulus will influence the frequency response. The increase of the thickness or the Young's modulus of the shell leads to the increase of the resonance frequency and the decrease of the oscillation amplitude of the microbubble. © 2013 Springer-Verlag.


Wang X.-J.,Ganzhou Tumor Hospital | Qiu X.-H.,Gannan Medical University
IFMBE Proceedings | Year: 2015

Estimation of tissue temperature in Tumor Hyperthermia is an extremely important assurance of therapeutic safety. In all kinds of measuring methods, ultrasonic nondestructive techniques are the safest and the most promising one. The main ultrasonic methods of temperature measurement are based on ultrasonic echo signal, acoustic transmission signal, the characteristic parameters of ultrasonic image, theoretical model simulation and so on. The theories of various ultrasonic methods adopted for measuring tissue temperature are introduced in this paper with their application, limitation and research status analyzed respectively. © Springer International Publishing Switzerland 2015.


Zhang X.,Ganzhou Tumor Hospital | Liu F.,Gannan Medical University | Lan X.,Ganzhou Tumor Hospital | Luo K.,Ganzhou Tumor Hospital | Li S.,Ganzhou Institute of Cancer Research
World Journal of Surgical Oncology | Year: 2014

Background: The growth of aging populations in an increasing number of countries has led to a concomitant increase in the incidence of chronic diseases. Accordingly, the proportion of older aged patients with oral cavity and oropharyngeal cancers and comorbidities has also increased. Thus, improvements must be made in the tolerance and safety of surgical procedures for these patients with complex medical conditions. In this study, we investigated combined submandibular gland flap and sternocleidomastoid musculocutaneous flap for postoperative reconstruction in older aged patients with oral cavity and oropharyngeal cancers in terms of surgical methods, safety, and clinical outcome.Methods: Between January 2011 and May 2012, 8 patients over the age of 65 years (7 men, 1 woman; aged 66 to 75 years (median, 69.6)) with oral cavity and oropharyngeal cancers underwent combined submandibular gland and sternocleidomastoid myocutaneous flaps for postoperative reconstruction at Ganzhou Tumor Hospital. All eight patients had comorbid cardiovascular, cerebrovascular, or chronic respiratory disease or diabetes. Clinical outcomes, complications, and tolerance to surgical treatment were observed.Results: Surgical treatment was successful in all eight patients. All submandibular gland flaps survived with well-mucosalized surfaces and with no complications. During the postoperative follow-up period of 12 to 28 months, no patient developed local recurrence or distant metastasis, and all had good recovery of function and local contour.Conclusions: This combined reconstruction technique enables appropriate restoration of oral function, facial aesthetics and improved quality of life. Further, this technique has several advantages: it is easier to perform, reduces operation time and surgical risk, causes less surgical injury, and has minor impact on contour. The technique provides a new and safe reconstruction option for older aged patients with oral cavity and oropharyngeal cancers. © 2014 Zhang et al.; licensee BioMed Central Ltd.

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