Liu X.S.,Gansu Hospital of TCM
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2013
To optimize the preparation technology of Shangke Jiefu lotion. The extraction process was optimized by orthogonal test, with water addition, extraction times and time used for extraction as factors of investigation. In refined process test, alcohol precipitation concentration, time, and the relative density of extract were studied. Each factor had three levels. The content of sophorcarpidine and the yield of dry extract were used as the evaluation indexes. The content of sophorcarpidine was determined by HPLC, and dry extract rates were determined by drying method. The best extraction condition was as follows: the amount of water was 10 times of the medicinal materials, the decoction duration was 2 h and for 3 times. The optimum purification process was: alcohol precipitation concentration was 50%, time was 15 hours, relative density of extract was 1.05 g/mL. The optimized preparation technology of Shangke Jiefu lotion is stable, feasible and convenient. It provides a theoretical basis for standardized production.
Liu Y.-J.,Gansu Hospital of TCM |
Wang D.-H.,General Hospital of Lanzhou |
Sheng L.,Gansu Hospital of TCM |
Li L.,Gansu Hospital of TCM |
And 2 more authors.
Journal of Xi'an Jiaotong University (Medical Sciences) | Year: 2011
Objective: To observe the effects of Huixiangzhizhu Soup (HX-S) on D-lactic acid in rats with adhesive intestinal obstruction and provide experimental evidence for the relationship between D-lactic acid change and adhesive intestinal obstruction of HX-S. Methods: The Wistar rat model of adhesive intestinal obstruction was constructed. Totally 180 rats were randomly divided into normal group, model group, Dachengqi Soup (DS) group, HX-S low dosage (HX-SL) group (1.13 g/mL), HX-S medium dosage (HX-SM) group (2.25 g/mL) and HX-S high dosage (HX-SH) group (3.38 g/mL). The rats were killed on day 3, 5 and 7 of treatment, respectively, and at each time point 6 rats were selected in each subgroup. The level of D-lactic acid in the femoral artery was determined by Brandt method. Results: Compared with that in normal group, the level of plasma D-lactic acid was increased obviously (P<0.05). Compared with that in model group, the level of plasma D-lactic acid was decreased obviously in DS group, HX-SL group, HX-SM group and HX-SH group (P<0.01). Conclusion: HX-S has a good effect in treating adhesive intestinal obstruction.
Kan L.L.,Gansu Hospital of TCM |
Wang H.D.,Gansu Hospital of TCM |
Liu A.G.,Gansu Hospital of TCM
Zhongguo gu shang = China journal of orthopaedics and traumatology | Year: 2013
To assess the efficacy of cervical spondylosis by needle-knife treatment according to the correlated literature of RCT,to compare advantages of needle-knife treatment. Randomized Controlled Trials about needle-knife treatment of cervical spondylosis were indexed from Chinese HowNet (CNKI) and Wanfang (WF) from 2000 to 2012, then were analyzed the efficacy by Review Manager 5.1 software. A total of 13 RCT literatures and 1 419 patients were included. The methods of included studies were poor in quality evaluation because of large sample and multi-center RCT studies was lacked, randomization method was not accurate enough, diagnostic criteria and efficacy evaluation were various, only four studies described long-term efficacy, most of the literature didn't describe the adverse event and fall off,all studies did not use the blind method. The Meta analysis outcome showed overall efficiency of needle-knife therapy was better than acupuncture and traction. Needle-knife therapy compared with Acupuncture, the total RR = 0.19, 95% confidence interval was (0.15, 0.24), P < 0.000.01. Compared with traction therapy the total RR = 1.30, 95% confidence intervalwas (1.18,1.42), P < 0.00001. Compared with acupuncture therapy,the overall effectiveness of needle-knife therapy is higher;compared with traction therapy, although,needle-knife therapy has a high overall effectiveness, but because of the loss of total sample size, the outcome RCT researches to confirm.