Gangwon do Agicultural Research and Experiment Services

Gangwon, South Korea

Gangwon do Agicultural Research and Experiment Services

Gangwon, South Korea
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Park Y.H.,Gangwon do Agicultural Research and Experiment Services | Kim H.Y.,Gangwon do Agicultural Research and Experiment Services | Lim S.H.,Gangwon do Agicultural Research and Experiment Services | Kim K.H.,Gangwon do Agicultural Research and Experiment Services | And 3 more authors.
Journal of the Korean Society of Food Science and Nutrition | Year: 2012

The effects of ethanol extract from leaves of Eleutherococcus senticosu were evaluated on hyperlipidemic rats. Male SD rats were divided into a normal group, control (AIN-76 diet) group, Garcinia cambogia extract group, and AIN-76 diet group supplemented with ethanol extract from Eleutherococcus senticosu(EEES). The body weight of the AIN-76 group increased, whereas those of the Garcinia and EEES groups decreased. The serum total cholesterol of the AIN-76 group increased by 28.36% compared to the normal group, but decreased by only 27.15% in the Garcinia group and 25.47% in the EEES group. The serum triglyceride level of the AIN-76 group increased by 35.04% compared to the normal group, but decreased by only 26.76% in the Garcinia group and 37.54% in the EEES group. The serum HDL-cholesterol levels of the Garcinia and EEES groups increased compared to that of the AIN-76 group. The liver and epididymal adipose tissue weights of the EEES group decreased compared to those of the AIN-76 group. In measuring the concentration of triglycerides and total cholesterol level in the liver extracts, the AIN-76 group showed significant increases compared to the normal group, whereas the Garcinia and EEES groups showed a significant decrease compared to the AIN-76 group. These results indicate that the EEES group may improve lipid metabolism and reduce fat accumulation and body weight.


Lim S.-H.,Gangwon do Agicultural Research and Experiment Services | Kim H.-Y.,Gangwon do Agicultural Research and Experiment Services | Park M.H.,Gangwon do Agicultural Research and Experiment Services | Park Y.H.,Gangwon do Agicultural Research and Experiment Services | And 5 more authors.
Journal of the Korean Society of Food Science and Nutrition | Year: 2010

In this study, the bioactivities of ethanol (EEAR) and water extract (WEAR) from the leaf of Aceriphyllum rossii were investigated. In the anti-oxidative activity, IC 50 of DPPH radical scavenging activity was respectively 549.86 and 62.14 μg/mL by EEAR and WEAR. Anti-inflammatory activity of EEAR and WEAR has been evaluated on inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) release by the macrophage RAW 264.7 cells. EEAR and WEAR inhibited inflammatory by 5.58 and 16.85% in 10 mg/mL, respectively. In the anti-diabetic activity, IC50 of α-glucosidase inhibitory activity was 5.62 and 425.63 μg/mL by EEAR and WEAR. IC 50 of α-amylase inhibitory activity of EEAR and WEAR was 4,623.87 and over 10,000 μg/mL, respectively. In the anti-obesity, all lipase inhibitory activity (IC 50) of EEAR and WEAR was up 10,000 μg/mL. Finally, EEAR and WEAR exhibited anti-oxidative and anti-diabetic activity. It suggests that Aceriphyllum rossii could be potentially used as a resource of bioactive materials for health functional foods.

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