Meerovich G.A.,RAS A.M. Prokhorov General Physics Institute |
Tiganova I.G.,Nf Gamaleya Federal Research Center For Epidemiology And Microbiology |
Makarova E.A.,Organic Intermediates and Dyes Institute |
Meerovich I.G.,Russian Academy of Sciences |
And 11 more authors.
Journal of Physics: Conference Series | Year: 2016
This work is devoted to the study of two new synthetic bacteriochlorins with four and eight cationic substitutes as the photosensitizers in the photodynamic process. The spectral and antibacterial properties of these photosensitizers in saline solution were investigated. It is shown, that the aggregation ability decreases and the antibacterial efficiency grows as the cationic substitute number increases. © Published under licence by IOP Publishing Ltd. Source
Voronina O.L.,Nf Gamaleya Federal Research Center For Epidemiology And Microbiology |
Kunda M.S.,Nf Gamaleya Federal Research Center For Epidemiology And Microbiology |
Ryzhova N.N.,Nf Gamaleya Federal Research Center For Epidemiology And Microbiology |
Aksenova E.I.,Nf Gamaleya Federal Research Center For Epidemiology And Microbiology |
And 5 more authors.
BioMed Research International | Year: 2015
Background and Aim: The order Burkholderiales became more abundant in the healthcare units since the late 1970s; it is especially dangerous for intensive care unit patients and patients with chronic lung diseases. The goal of this investigation was to reveal the real variability of the order Burkholderiales representatives and to estimate their phylogenetic relationships. Methods: 16S rDNA and genes of the Burkholderia cenocepacia complex (Bcc) Multi Locus Sequence Typing (MLST) scheme were used for the bacteria detection. Results: A huge diversity of genome size and organization was revealed in the order Burkholderiales that may prove the adaptability of this taxon's representatives. The following variability of the Burkholderiales in Russian healthcare units has been revealed: Burkholderiaceae (Burkholderia, Pandoraea, and Lautropia), Alcaligenaceae (Achromobacter), and Comamonadaceae (Variovorax). The Burkholderia genus was the most diverse and was represented by 5 species and 16 sequence types (ST). ST709 and 728 were transmissible and often encountered in cystic fibrosis patients and in hospitals. A. xylosoxidans was estimated by 15 genotypes. The strains of first and second ones were the most numerous. Conclusions: Phylogenetic position of the genus Lautropia with smaller genome is ambiguous. The Bcc MLST scheme is applicable for all Burkholderiales representatives for resolving the epidemiological problems. © 2015 Olga L. Voronina et al. Source