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Seongnam, South Korea

Gachon University is an academic institute located in South Korea. The current structure of Gachon university is the result of a merger between four existing universities. Gachon University of Medicine and Science and Gachon-gil College merged in 2007, Kyungwon University and Kyungwon College merged in 2007, and Gachon University of Medicine and Science and Kyungwon University merged in 2012. Gachon University has three campuses for undergraduates, the Global Campus located in Seongnam, satellite campuses on Ganghwa Island and in Yeonsu-dong, and the School of Medicine in Guwol-dong, Namdong-gu, Incheon, South Korea. Gachon University signed a strategic partnership with Hawaii Pacific to allow students to study abroad. " Wikipedia.

Thimmapuram P.R.,Argonne National Laboratory | Kim J.,Gachon University
IEEE Transactions on Smart Grid | Year: 2013

Automated Metering Infrastructure (AMI) is a technology that would allow consumers to exhibit price elasticity of demand under smart-grid environments. The market power of the generation and transmission companies can be mitigated when consumers respond to price signals. Such responses by consumers can also result in reductions in price spikes, consumer energy bills, and emissions of greenhouse gases and other pollutants. In this paper, we use the Electricity Market Complex Adaptive System (EMCAS), an agent-based model that simulates restructured electricity markets, to explore the impact of consumers' price elasticity of demand on the performance of the electricity market. An 11-node test network with eight generation companies and five aggregated consumers is simulated for a period of one month. Results are provided and discussed for a case study based on the Korean power system. © 2012 IEEE. Source

Cheon H.G.,Gachon University
Handbook of Experimental Pharmacology | Year: 2012

Despite remarkable progress in the elucidation of energy balance and regulation, the development of new antiobesity drugs is still at the stage of infancy. This review describes the MCH and MCH receptor system with regard to its involvement in energy homeostasis and summarizes the pharmacological profiles of selected small molecule MCH-R1 antagonists that are relevant for their development as antiobesity drugs. Although their clinical value still has to be demonstrated, and challenges with regard to unwanted side effects remain to be resolved, MCH-R1 antagonists may provide an effective pharmacotherapy for the treatment of obesity in the near future. © 2012 Springer-Verlag Berlin Heidelberg. Source

Jeong K.W.,Gachon University
Biochemical and Biophysical Research Communications | Year: 2014

The coordinated activities of multiple protein complexes are essential to the remodeling of chromatin structure and for the recruitment of RNA polymerase II (Pol II) to the promoter in order to facilitate the initiation of transcription in nuclear receptor-mediated gene expression. Flightless I (Drosophila) homolog (FLII), a nuclear receptor coactivator, is associated with the SWI/SNF-chromatin remodeling complex during estrogen receptor (ER)α-mediated transcription. However, the function of FLII in estrogen-induced chromatin opening has not been fully explored. Here, we show that FLII plays a critical role in establishing active histone modification marks and generating the open chromatin structure of ERα target genes. We observed that the enhancer regions of ERα target genes are heavily occupied by FLII, and histone H3K4me3 and Pol II binding induced by estrogen are decreased in FLII-depleted MCF-7 cells. Furthermore, formaldehyde-assisted isolation of regulatory elements (FAIRE)-quantitative polymerase chain reaction (qPCR) experiments showed that depletion of FLII resulted in reduced chromatin accessibility of multiple ERα target genes. These data suggest FLII as a key regulator of ERα-mediated transcription through its role in regulating chromatin accessibility for the binding of RNA Polymerase II and possibly other transcriptional coactivators. © 2014 Elsevier Inc. All rights reserved. Source

Naturally immiscible PEDOT:PSS and PDMS, which are a typical conducting polymer and an transparent elastomer, respectively, were blended by the support of PDMS-b-PEO. A block copolymer, PDMS-b-PEO, consisting of hydrophobic PDMS backbones and hydrophilic PEO side chains, significantly improved the miscibility of PEDOT:PSS and PDMS. At an optimal PDMS-b-PEO concentration of 30%, a cured PEDOT:PSS:PDMS film was found to be comprised of three-dimensional PDMS networks and a PEDOT:PSS phase filling in between the networks. The optimal blend film exhibited a conductivity comparable to a pure PEDOT:PSS film and a maximum strain to rupture of about 75%. It was also demonstrated that interconnects made of this blend film functioned well irrespective of the substrate and the pattern size, and could reproducibly operate under strains up to 50%. These results indicate that the PEDOT:PSS:PDMS blends could be a practical choice for organic interconnects for future stretchable electronics. © 2014 The Royal Society of Chemistry. Source

Han E.,Gachon University | Powell L.M.,University of Illinois at Chicago
Journal of the Academy of Nutrition and Dietetics | Year: 2013

Background Few previous studies have investigated consumption distributions of sugar- sweetened beverages (SSBs) over time and individual-level associations despite recent interest in SSBs regarding obesity control. Objective To assess consumption patterns and individual-level associations. Design Trend and cross-sectional analyses of 24-hour dietary recall data and demographic characteristics and socioeconomic status (SES) drawn from National Health and Nutrition Examination Survey (1999-2000, 2001-2002, 2003-2004, 2005-2006, and 2007-2008) data. Participants/setting Children (aged 2 to 11 years, n=8,627), adolescents (aged 12 to 19 years, n=8,922), young adults (aged 20 to 34 years, n=5,933), and middle-aged and elder adults (aged ≥35 years, n=16,456). Statistical analyses performed Age-stratified regression analyses for SSBs overall and by subtypes. Results The prevalence of heavy total SSB consumption (≥500 kcal/day) increased among children (4% to 5%) although it decreased among adolescents (22% to 16%) and young adults (29% to 20%). Soda was the most heavily consumed SSB in all age groups except for children. Prevalence of soda consumption decreased, whereas heavy sports/ energy drink consumption tripled (4% to 12%) among adolescents. Black children and adolescents showed higher odds of heavy fruit drink consumption (odds ratios 1.71 and 1.67) than whites. Low-income children had a higher odds of heavy total SSB consumption (odds ratio 1.93) and higher energy intake from total SSBs and fruit drinks (by 23 and 27 kcal/day) than high-income children. Adolescents with low- vs high-educated parents had higher odds of heavy total SSB consumption (odds ratio 1.28) and higher energy intake from total SSBs and soda (by 27 and 21 kcal/day). Low vs high SES was associated with a higher odds of heavy consumption of total SSBs, soda, and fruit drinks among adults. Conclusions Prevalence of soda consumption fell, but consumption of nontraditional SSBs rose. Heterogeneity of heavy consumption by SSB types across racial/ethnic subpopulations and higher odds of heavy SSB consumption among low-SES populations should be considered in targeting policies to encourage healthful beverage consumption. © 2013 Academy of Nutrition and Dietetics. Source

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