Florianópolis, Brazil
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PubMed | FUNDACENTRO, University of Campinas, University of Sao Paulo and b Workers Health Programme
Type: | Journal: Inhalation toxicology | Year: 2015

This study investigated the relative contribution of asbestos-related pleural thickening (PT) to lung function indices and to respiratory symptoms. A group of 828 former asbestos cement workers enrolled in a cross-sectional and cohort study of respiratory morbidity and submitted to a detailed occupational history, respiratory symptoms questionnaire, spirometry, postero-anterior chest x-ray, and high-resolution computed chest tomography (HRCT). Asbestos exposure was assessed by years of exposure (a semi-quantitative method), cumulative exposure, and latency time from first exposure. Smoking was assessed in pack-years. PT and asbestosis were assessed according to HRCT criteria. Statistical analysis included descriptive analysis, univariate and multivariate analysis of variance for comparisons of factors related to PT, stepwise multiple regression analysis for continuous dependent variables, and logistic regression analysis for dichotomous dependent variables. Mean age was 51.4 (SD 10.5) years, mean years of exposure 12.4 (SD 8.8), mean cumulative exposure 79.9 (SD 68.5), and mean latency time 25.2 yr (SD 10.4). Of the 828, 238 (28.7%) were smokers, 288 (34.8%) former smokers, and 302 (36.2%) nonsmokers. PT was present in 246 (29.7%) and asbestosis in 74 (8.9%); 97 (11.9%) had shortness of breath of Grade III or more. PT subjects had lower height-adjusted forced vital capacity (FVC) and forced expiratory volume in I s (FEV1) and lower FEV1/FVC% (p < .00001 for all). Variables significantly related to PT were age (p < .000 1), years of exposure (p < .0000 1), cumulative exposure (p < .00001), latency time (p < .00001), pack-years (p < .0000 1), and asbestosis (p < .00 1). In a multiple stepwise regression model, after controlling for confounders, height adjusted FEV1 and FVC were in versely and significantly associated with PT, mainly when associated with asbestosis. A logistic regression model with shortness of brea th as the dependent va riable, con trolled for confounders, showed that PT was significa ntly associated with the symptom, even without asbestosis. In conclusion, PT is independently associated with lower va lues of FEV1 and FVC. PT is also independently associated with an increased risk of shortn ess of breath report. PT should be considered as a disease for clinical follow up and for compensa tion claims.


The Revista Brasileira de Saúde Ocupacional (RBSO) - Brazilian Journal of Occupational Health - is an academic peer-reviewed journal in the field of Workers’ Health that has been published by Fundacentro since 1973. Its historical trajectory, current performance, challenges and future perspectives were approached, in this paper, from a documental analysis. The journal’s history can be divided into three periods, starting during the military government. At the beginning, the journal was the official vehicle for the Brazilian occupational accidents prevention policy, in which Fundacentro played a central role. The early 1980s opens space for technical-scientific publications and the field of Workers’ Health emerges on the journal’s pages. In 2005-6, a restructuring process is implemented, ensuring independent editorial policy and structures. Since 2006, 139 original papers and 9 thematic issues have been published. The journal is indexed in 9 bibliographic databases, has been ranked B1 in the field of interdisciplinary studies and B2 in the field of public health by CAPES, has an upward trend in the SciELO Impact Factor, and has an h-index of 5 in Google Scholar. Nevertheless, the low scientific production in the field and the high rate of rejection of manuscripts may jeopardize the survival of the journal, which is the main locus for scientific publications in the field of Workers’ Health. © 2015, Associacao Brasileira de Pos – Graduacao em Saude Coletiva. All rights reserved.


Maia P.A.,Fundacentro | Ruas A.C.,Fundacentro | Bitencourt D.P.,Fundacentro
International Journal of Biometeorology | Year: 2015

It is well known that excessive heat exposure causes heat disorders and can lead to death in some situations. Evaluation of heat stress on workers performing indoor and outdoor activities is, nowadays, conducted worldwide by wet-bulb globe temperature (WBGT) index, which calculation parameters are dry-bulb, natural wet-bulb, and globe temperatures, which must be measured at the same time and in location where the worker is conducting his/her activities. However, for some activities performed in large outdoor areas such as those of agricultural ones, it is not feasible to measure directly those temperatures in all work periods and locations where there are workers. Taking this into account, this work aims to introduce a WBGT index estimation using atmospheric variables observed by automatic meteorological stations. In order to support our estimation method, we used, as a test-bed, data recorded in the State of São Paulo (SP), Brazil. By adding the cloudiness factor in the calculation through measurement of solar radiation, the algorithm proved to be as efficient as those mentioned in this work. It was found that this method is viable, with WBGT-estimated values obtained from meteorological data measured by stations with a distance of less than 80 km. This estimate can be used for monitoring heat stress in real time as well as to investigate heat-related disorders and agricultural work. © 2015, ISB.


Algranti E.,FUNDACENTRO | Mendonca E.M.C.,FUNDACENTRO | Hnizdo E.,U.S. National Institute for Occupational Safety and Health | De Capitani E.M.,University of Campinas | And 3 more authors.
Occupational and Environmental Medicine | Year: 2013

Background: This study was designed to assess the effect of asbestos exposure on longitudinal lung function decline. Methods: A group of 502 former asbestos-cement workers with at least two spirometry tests 4 years apart. Repeated evaluations included respiratory symptoms questionnaire, spirometry and chest imaging. Asbestos exposure was ascertained as years of exposure, an index of cumulative exposure and latency time. The mixed effects model was used to evaluate the effect of exposure on the level and rate of change in forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). Results: Mean age at entry was 51 (SD 9.9) years, mean latency time 25.6 (SD 10.0) years, mean follow-up time 9.1 (SD 2.8) years and mean number of spirometry tests 3.5. The FEV1 level was significantly related to pack-years of smoking at entry and during the follow-up, the index of cumulative asbestos exposure at entry, and the presence of asbestosis at follow-up. The FVC level was signi ficantly related to pack-years of smoking during the follow-up, cumulative asbestos exposure at entry, asbestosis and pleural thickening at follow-up, and body mass index at entry. Asbestos exposure was not associated with increasing rates of FEV1 and FVC decline. However, FEV1 regression slopes with age, estimated by terciles of cumulative exposure, showed significant differences. Combined effects of smoking and exposure conferred further acceleration in lung function decline. Conclusions: Occupational exposure in asbestoscement industry was a risk factor for increased lung function decline. The effect seems to be mostly concentrated during the working period. Smoking and exposure had synergic effects.


Galante E.B.F.,Military Institute of Engineering of Rio de Janeiro | Costa D.M.B.,University of Porto | Franca T.C.C.,Military Institute of Engineering of Rio de Janeiro | Viaro R.S.,Fundacentro
Occupational Safety and Hygiene IV - Selected, Extended and Revised Contributions from the International Symposium Occupational Safety and Hygiene, 2016 | Year: 2016

This paper is about risks in 12 standard chemical laboratories, aiming to evaluate the Occupational Health and Safety (OHS) of its professionals. The studied laboratory is used by universities and research institutes. Inspections and evaluations were conducted within onsite audits and legal compliance verification, considering key Brazilian regulatory standards. Using a hazard identification method based on checklists and inspections on side, seven risk scenarios were selected and evaluated through the Preliminary Hazard Analysis (PHA). These seven scenarios were considered general to all evaluated facilities, since in one way or another they were identified in all the facilities under study. Using the frequency and severity parameters from the PHA methodology we were able to, using a risk matrix, determine risk levels. As a results there were three scenarios classified as high-risk, two as serious risk and two as medium risk, demonstrating the relevance of raising strong OHS procedures and standards in the studied environments. © 2016 Taylor & Francis Group, London.


Garrigou A.,University of Bordeaux 1 | Garrigou A.,University of Bordeaux Segalen | Baldi I.,University of Bordeaux Segalen | Jackson M.,Fundacentro
Work | Year: 2012

The use of pesticides is one of the techniques employed in modern agriculture and in particular in intensive agriculture. The risks for the environment and for worker health have been debated in western countries for about ten years. Recent developments in epidemiology, toxicology and ergotoxicology have clearly revealed that pesticides could harm the health of farmers (cancers, neurological diseases and reproductive disorders). Failures and shortcomings in the risk prevention systems have also come to light. This paper aims to address the risks associated to the use of pesticides in French vineyards. The chosen approach draws from an anthropological approach as well as from developments in ergotoxicology applied to the French vineyard work. We shall discuss the use of pesticides from the point of view of the transfer of technology. Our recent research has shown that this technology transfer was not completely controlled by the different stakeholders. © 2012 - IOS Press and the authors. All rights reserved.


Pinto T.N.O.,Fundacentro | Pinto T.N.O.,Brazilian Nuclear Energy Research Institute (IPEN) | Caldas L.V.E.,Brazilian Nuclear Energy Research Institute (IPEN)
Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment | Year: 2010

In recent years, the optically stimulated luminescence (OSL) technique has been used in personal dosimetry, and aluminum oxide (Al2O 3:C) has become a very useful material for this technique. The objective of this work was the determination of the transmission factors for beta radiation using Al2O3:C commercial dosimeters and the OSL method. The obtained results were similar to the transmission factors reported in the beta source calibration certificates. © 2009 Elsevier B.V.


Querol M.P.,University of Helsinki | Seppanen L.,Finnish Institute of Occupational Health | Filho J.M.J.,FUNDACENTRO
Producao | Year: 2015

Despite the importance of the expectations and visions of the actors involved in sustainable innovations, only the societal, motivational perspective is usually considered. The fact that local actors may have different multi-motivations is typically overlooked. The aim of this study is to examine and understand the multi-motivational perspectives in a sustainable production project. First, we introduce the concept of the object and analyze the case of a biogas production project as a mediating activity for making swine production more sustainable. We argue that the object of the activity, as manifested in motivational perspectives, shapes the way in which biogas production (BP) systems are implemented. The article concludes by discussing how the concept of object can be used to explore the actual and future possibilities of using artifacts for increasing the sustainability of production.


Filho J.M.J.,Fundacentro | Fonseca E.D.,Fundacentro | Lima F.P.A.,Federal University of Minas Gerais | Duarte F.J.C.M.,Federal University of Rio de Janeiro
Work | Year: 2012

The purpose of this paper is to understand the influence of organizational factors on occupational accident causation. A field study was undertaken and focused on the phase of concreting the floors of a residential block in a building project in Brazil. The methodological approach was based on the analysis of carpenters' work practices and of the workers' accounts of minor falls. Observations were noted on work practices over this stage. Furthermore, interviews were conducted with the workers hired by the subcontractors and with professionals working for the main contractor. The results show that falls were related to the introduction of new building technology and its use by the workforce. The production planning and organization of activities by the subcontracted firms also led to temporary demands that were additional determining factors for falls on site. The work analysis reveals the need to consider organizational factors in prevention practices. © 2012 - IOS Press and the authors. All rights reserved.


PubMed | FUNDACENTRO and Federal University of Minas Gerais
Type: Journal Article | Journal: Cancer epidemiology | Year: 2015

There are limited data on mesothelioma mortality in industrializing countries, where, at present, most of the asbestos consumption occurs.To analyze temporal trends and to calculate mortality rates from mesothelioma and cancer of the pleura in Brazil from 2000 to 2012 and to estimate future mortality rates.We retrieved records of deaths from mesothelioma (ICD-10C45) and cancer of the pleura (ICD-10C38.4) from 2000 to 2012 in adults aged 30 years and over. Crude and age-standardized mortality rates (ASMR) were calculated. Rate ratios of mean crude mortality for selected municipalities were compared to the Brazilian rate. A regression was carried out of the annual number of deaths against asbestos consumption using a Generalized Additive Model (GAM). The best model was chosen to estimate the future burden and peak period of deaths.There were 929C45 and 1379 C38.4 deaths. The ratio of men to women for C45 was 1.4. A positive trend in C45 numbers was observed in Brazil (p=0.0012), particularly in So Paulo (p=0.0004) where ASMRs presented an increasing linear trend (p=0.0344). Selected municipalities harboring asbestos manipulation presented 3.7-11 fold rate ratios of C45 compared to Brazil. GAM presented best fits for latencies of 34 years or more. It is estimated that the peak incidence of C45 mortality will occur between 2021 and 2026.The observed ASMRs and the gender ratio close to 1 suggest underreporting. Even so, deaths are increasing and mesothelioma clusters were identified. Compared to industrialized countries Brazil displays a 15-20 year lag in estimated peak mesothelioma mortality which is consistent with the lag of asbestos peak consumption in the country.

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