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Owada Y.,Fukushima Medical University | Yaginuma H.,Fukushima Medical University | Hasegawa T.,Fukushima Medical University | Ohsugi J.,Fukushima Medical University | And 2 more authors.
Japanese Journal of Lung Cancer | Year: 2014

Background. Although the pattern of lung cancer progression varies, reports of lung cancer lesions invading the retroperitoneal space through the diaphragm are rare. We herein report an extremely rare case of lung cancer that directly invaded the retroperitoneal space. Case. A 64-year-old male presented to his local physician for an evaluation of night sweats and a body weight loss of 5 kg. An examination revealed a 90-mm tumor extending from the upper pole of the right kidney to the dorsal side of the right liver lobe. After excluding the possibility of pheochromocytoma and adrenal carcinoma, the patient was diagnosed with a retroperitoneal tumor and underwent laparotomy for tumor resection. Intraoperatively, the border between the peritoneum-covered tumor and the adrenal gland was clear. However, the tumor had invaded the diaphragm, and combined resection of the diaphragm was thus performed. Furthermore, a portion of the tumor appeared to have infiltrated the lung within the thoracic cavity; therefore, partial resection of the right lower lung lobe was also performed. An immunohistochemical examination of the resected specimen revealed a diagnosis of lung adenocarcinoma. We concluded that the primary lung tumor had directly invaded the retroperitoneal space through the diaphragm. Vertebral body infiltration and local recurrence in the retroperitoneal space were detected two months after surgery, and radiation and chemotherapy were subsequently administered. Despite treatment with this multimodal therapy, the patient died 257 days after surgery. Conclusions. Lung cancer that directly invades the retroperitoneal space is rare, although it can occur. © 2014 The Japan Lung Cancer Society.

Gotoh M.,Fukushima Rosai Hospital
Fukushima journal of medical science | Year: 2011

Although several studies have reported a lower risk of osteoporotic fracture in hypercholesterolemic patients (WHO IIa) treated with statin, longitudinal studies on the effects of statins on bone are lacking. The aim of the present study was to evaluate bone mineral density (BMD) and bone turnover changes induced by 3-year fluvastatin treatment in postmenopausal women. Twenty-eight consecutive postmenopausal non-diabetic, normotensive hypercholesterolemic women (64.0±3.6 years) were treated for 36 months with 30 mg/day fluvastatin and 28 non-diabetic, normotensive normocholesterolemic age- and body mass index-matched postmenopausal women served as the control subjects. The result revealed a significant increase of the BMD as compared with the level at the base line (p< 0.001) in the fluvastairn-treated group, from 6 months on ward after the start treatment. Significant differences of the BMD were found between the controls and fluvastatin-treated group (p< 0.001) were at 6, 12, 24 and 36 months after the start of the study. In conclusion our results, although obtained small sample of postmenopausal hypercholesterolemic women, suggest a probable favorable effect of fluvastatin on bone formation and BMD.

Watanabe T.,University of Occupational and Environmental Health Japan | Watanabe T.,Kyusyu Rosai Hospital Moji Medical Center | Kume K.,University of Occupational and Environmental Health Japan | Tai M.,Fukushima Rosai Hospital | And 4 more authors.
Hepato-Gastroenterology | Year: 2010

Background/Aims: Recently, endoscopic submucosal dissection (ESD) has been accepted for the treatment of gastrointestinal mucosal neoplasms because of the higher en bloc resection rate. However, ESD is technically more difficult, requires a longer procedure time and has more frequent complications compared with conventional endoscopic mucosal resection (EMR). We evaluated retrospectively the clinical outcomes of ESD compared with EMR to determine the size of the lesion for choosing EMR rather than ESD. Methodology: Three hundred and sixty-five lesions of early gastric cancer were treated endoscopically (146 by EMR and 219 by ESD). We compared en bloc resection, residual tumor and recurrence-free rates between EMR and ESD. Results: En bloc resection rate was significantly higher with ESD (88.5%) than EMR (45.2%). With regard to lesions ≤7mm in size, en bloc resection, residual tumor and recurrence-free rates did not differ. Conclusions: Gastric mucosal cancer ≤7mm can be treated with EMR as effectively as with ESD. © H.G.E. Update Medical Publishing S.A.

Amagai T.,Mukogawa Womens University | Ichimaru S.,Mukogawa Womens University | Ichimaru S.,Kobe City Medical Center General Hospital | Tai M.,Fukushima Rosai Hospital | And 2 more authors.
Nutrition in Clinical Practice | Year: 2014

The Great East Japan Earthquake Disaster (GEJED) struck the northeast region of Honshu, the main island of Japan, on March 11, 2011. This mega-disaster claimed more than 15,000 lives, with approximately 3000 later deaths being disaster related. The GEJED consisted of a mega-earthquake, tsunami, and nuclear accident. Survivors living in temporary shelters might have received insufficient levels of vitamins, with the exception of vitamin B1, which appeared to be overestimated, and excess levels of sodium. However, scientific data collection and surveys following the GEJED were extremely limited. This experience highlights the need to prepare an "emergency nutrition assessment" system for optimal nutrition in future disasters. © 2014 American Society for Parenteral and Enteral Nutrition.

Sasaji T.,Fukushima Rosai Hospital | Yamada N.,Fukushima Rosai Hospital | Iwai K.,Fukushima Rosai Hospital
Upsala Journal of Medical Sciences | Year: 2012

Pyogenic spondylitis is a common infectious disease caused by various microorganisms. It is difficult to predict the infecting microorganism at the time of initiation of treatment. Pneumonia is generally clarified into community or hospital-acquired types based on where the infection was acquired, and the infecting microorganisms are different for each type. We retrospectively analyzed 20 cases of pyogenic spondylitis treated in our hospital and categorized the cases into community and hospital-acquired types. We also identified the infecting microorganisms and the rate of sepsis in each type. There were 12 cases of community-acquired and 8 of hospital-acquired infection. The major infecting microorganisms responsible for the community-acquired type were Gram-positive cocci, and those responsible for the hospital-acquired type were methicillin-resistant Staphylococcus aureus and Gram-negative bacilli. The rate of sepsis was significantly different for both groups: 16% for the community-acquired type and 75% for the hospital-acquired type. The classification of pyogenic spondylitis based on where the infection was acquired may be useful for predicting which microorganisms are responsible for the disease. © 2012. Informa Healthcare.

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