Fuji Chemical Industry Co.

Tokyo, Japan

Fuji Chemical Industry Co.

Tokyo, Japan

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The object of the present invention is to find a carotenoid compound that is excellent in water solubility. A carotenoid derivative having a formula (I):X represents a carbonyl group or a methylene group, one of R^(1) and R^(2) represents (a) or (b) and the other represents (a), (b), (c) or a hydrogen atom:(a): -CO-A-B-D wherein A represents an alkylene group an alkenylene group, etc., B represents a formula of -S(O)_(n)- or a formula of -NR^(4)CONR^(5)- and D represents a hydrogen atom, a carboxy group, etc.,(b): -CO-E-F wherein E represents an alkylene group or a formula of -NR^(3)- wherein R^(3) represents (a1) a hydrogen atom, (b1) an alkyl group etc., and F represents a sulfo group and(c): -CO-G wherein G represents a hydrogen atom, an alkyl group, 1 etc.,a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester or amide thereof.


Patent
The Doshisha and Fuji Chemical Industry Co. | Date: 2017-02-02

An oral composition that improves intestinal flora via oral intake includes astaxanthin as an active ingredient, and excludes a component that can form skin tissue, the composition improving the intestinal flora by reducing or suppressing either or both of an increase in gram-negative bacteria and an increase in bacteria that belong to the Clostridium coccoides group.


Patent
The Doshisha and Fuji Chemical Industry Co. | Date: 2016-07-06

An oral composition improves the balance of intestinal flora via oral intake. The oral composition that improves intestinal flora via oral intake includes astaxanthin as an active ingredient, and excludes a component that can form skin tissue, the composition improving the intestinal flora by reducing or suppressing either or both of an increase in gram-negative bacteria and an increase in bacteria that belong to the Clostridium coccoides group.


Patent
The Doshisha and Fuji Chemical Industry Co. | Date: 2015-12-24

An oral composition that improves intestinal flora via oral intake includes astaxanthin as an active ingredient, and excludes a component that can form skin tissue, the composition improving the intestinal flora by reducing or suppressing either or both of an increase in gram-negative bacteria and an increase in bacteria that belong to the Clostridium coccoides group.


Patent
Fuji Chemical Industry Co. and Naito | Date: 2013-10-23

To provide a gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester. Abnormal gene expression due to, for example, oxidative stress can be treated, improved, and/or prevented, and diseases caused by the abnormal gene expression can be treated, improved, and/or prevented. A gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester are provided and are useful for treating, improving, and/or preventing the symptom caused by the abnormal gene expression, that is, excessive expression or suppression of expression.


Patent
FUJI CHEMICAL INDUSTRY Co. | Date: 2014-10-29

An object of the invention is to provide a gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester. Abnormal gene expression due to, for example, oxidative stress can be treated, improved, and/or prevented, and diseases caused by the abnormal gene expression can be treated, improved, and/or prevented. A gene expression regulating agent which includes astaxanthin and/or its ester as an effective ingredient; and a food and drink having an effect of regulating gene expression which includes astaxanthin and/or its ester are provided and are useful for treating, improving, and/or preventing the symptom caused by the abnormal gene expression, that is, excessive expression or suppression of expression.


Patent
Fuji Chemical Industry Co. | Date: 2013-12-09

There is provided pet food comprising astaxanthin and/or an ester thereof as an active component and having an effect of deodorizing excrement such as urine and feces, effects of improving sleep, sensibility such as perception and cognition, and visual sense, and an effect of treating, improving or preventing diabetes and diabetic complications. The pet food can deodorize excrement such as urine and feces, improve sleep, sensibility such as perception and cognition, and visual sense, and treat, improve or prevent diabetes and diabetic complications.


Patent
Fuji Chemical Industry Co. | Date: 2012-06-20

Disclosed is an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity. The orally rapidly disintegrating tablet, which has a good texture and taste, an appropriate hardness, and good disintegrating properties, can be produced by using a composition, which is prepared by dispersing, by spray-drying, an inorganic excipient and starch(es) in complex particles composed of mannitol and xylitol, in an orally rapidly disintegrating tablet.


Patent
Fuji Chemical Industry Co. | Date: 2012-06-20

There has been a need for an orally rapidly disintegrating tablet which has a good texture and taste in the oral cavity, such a sufficient hardness as not giving any worry of being chipped or dusted during production or transportation and good disintegrating properties in the oral cavity and can sustain a sufficient hardness even under humid conditions after opening. Disclosed are a disintegrating particle composition which is prepared by dispersing, in the presence of water, mannitol, xylitol, an inorganic excipient, a disintegrating agent and carmellose and drying, and an orally rapidly disintegrating tablet which comprises said disintegrating particle composition, an active substance and a disintegrating agent. The disintegrating tablet has a good texture and taste, an appropriate hardness and good disintegrating properties and can sustain a sufficient hardness under humid conditions.


[Subject Matter] A rapidly disintegrating compression-molded material has been demanded, which exhibits good taking feeling and taste in the oral cavity, has a sufficient hardness for prevent the material from causing problems such as cracking or dusting during the preparation or distribution process, also has a good disintegrating property in the oral cavity, and can be taken in a large amount. [Means to Solve] A disintegrating particle composition is prepared by wet-granulating a starch, a water-soluble binding agent,, and if needed a molding agent/an effective ingredient. By incorporating this disintegrating particle composition, a rapidly disintegrating compression-molded material can be prepared which has an excellent taking feeling, taste, hardness and disintegrating property and can be taken without limitation in quantity.

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