The Commissariat à l'énergie atomique et aux énergies alternatives or CEA, is a French public government-funded research organisation in the areas of energy, defense and security, information technologies and health technologies. The CEA maintains a cross-disciplinary culture of engineers and researchers, building on the synergies between fundamental and technological research Wikipedia.
French Atomic Energy Commission | Date: 2017-03-22
The present invention pertains to a novel treatment of renal cell carcinoma and other a solid tumors which harbor a VHL inactivation, based on the combination of a first agent inhibiting a protein kinase CK2 (CK2) and a second agent inhibiting an Ataxia Telangiectasia Mutated (ATM) kinase.
French Atomic Energy Commission | Date: 2017-01-04
The invention relates to a fluid flow velocity sensor using a differential pressure measurement and comprising a stack (200) having a tip (230) pointing in a first direction, said stack comprising first and second plates (210A-210B) arranged in parallel one another along the first direction; and a pressure-sensitive diaphragm (220) arranged between the first and second plates (210A-210B) along the first direction, said pressure-sensitive diaphragm (220) being spaced apart from the first plate (210A) by a first cavity and from the second plate (210B) by a second cavity, wherein the first cavity is entirely sealed, except at the tip (230) of the stack, so as to be under a stagnation pressure during operation of the fluid flow velocity sensor, and wherein the second cavity is opened so as to be under a reference pressure during operation of the fluid flow velocity sensor. The fluid flow velocity sensor further comprises a detector configured to measure a parameter representative of the differential pressure between the first and the second cavities.
French Atomic Energy Commission and Umicore AG | Date: 2017-02-22
The present invention relates to an electrochemically active Si-carbon composite particulate material, wherein silicon nanoparticles are entrapped in a carbon matrix material based on at least micronic graphite particles, reduced graphene platelets and amorphous carbon.
French Atomic Energy Commission | Date: 2017-03-01
The present invention relates to a single nucleotide polymorphism (SNP) rs3815496 or any SNP having 100 % of linkage disequilibrium with this SNP as a biomarker for assessing the risk of developing adverse effects after radiotherapy in a subject, in particular acute and/or subacute dermatitis and lymphocyte apoptosis.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 25.77M | Year: 2017
ACTIVAGE is a European Multi Centric Large Scale Pilot on Smart Living Environments. The main objective is to build the first European IoT ecosystem across 9 Deployment Sites (DS) in seven European countries, reusing and scaling up underlying open and proprietary IoT platforms, technologies and standards, and integrating new interfaces needed to provide interoperability across these heterogeneous platforms, that will enable the deployment and operation at large scale of Active & Healthy Ageing IoT based solutions and services, supporting and extending the independent living of older adults in their living environments, and responding to real needs of caregivers, service providers and public authorities. The project will deliver the ACTIVAGE IoT Ecosystem Suite (AIOTES), a set of Techniques, Tools and Methodologies for interoperability at different layers between heterogeneous IoT Platforms and an Open Framework for providing Semantic Interoperability of IoT Platforms for AHA, addressing trustworthiness, privacy, data protection and security. User-demand driven interoperable IoT-enabled Active & Healthy Ageing solutions will be deployed on top of the AIOTES in every DS, enhancing and scaling up existing services, for the promotion of independent living, the mitigation of frailty, and preservation of quality of life and autonomy. ACTIVAGE will assess the socio-economic impact, the benefits of IoT-based smart living environments in the quality of life and autonomy, and in the sustainability of the health and social care systems, demonstrating the seamless capacity of integration and interoperability of the IoT ecosystem, and validating new business, financial and organizational models for care delivery, ensuring the sustainability after the project end, and disseminating these results to a worldwide audience. The consortium comprises industries, research centres, SMEs, service providers, public authorities encompassing the whole value chain in every Deployment Site.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 25.43M | Year: 2017
Automated driving is expected to increase safety, provide more comfort and create many new business opportunities for mobility services. The market size is expected to grow gradually reaching 50% of the market in 2035. The IoT is about enabling connections between objects or things; its about connecting anything, anytime, anyplace, using any service over any network. There is little doubt that these vehicles will be part of the IoT revolution. Indeed, connectivity and IoT have the capacity for disruptive impacts on highly and fully automated driving along all value chains towards a global vision of Smart Anything Everywhere. In order to stay competitive, the European automotive industry is investing in connected and automated driving with cars becoming moving objects in an IoT ecosystem eventually participating in BigData for Mobility. AUTOPILOT brings IoT into the automotive world to transform connected vehicles into highly and fully automated vehicle. The well-balanced AUTOPILOT consortium represents all relevant areas of the IoT eco-system. IoT open vehicle platform and an IoT architecture will be developed based on the existing and forthcoming standards as well as open source and vendor solutions. Thanks to AUTOPILOT, the IoT eco-system will involve vehicles, road infrastructure and surrounding objects in the IoT, with a particular attention to safety critical aspects of automated driving. AUTOPILOT will develop new services on top of IoT to involve autonomous driving vehicles, like autonomous car sharing, automated parking, or enhanced digital dynamic maps to allow fully autonomous driving. AUTOPILOT IoT enabled autonomous driving cars will be tested, in real conditions, at four permanent large scale pilot sites in Finland, France, Netherlands and Italy, whose test results will allow multi-criteria evaluations (Technical, user, business, legal) of the IoT impact on pushing the level of autonomous driving.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: ICT-29-2016 | Award Amount: 15.57M | Year: 2017
PIXAPP will establish the worlds first open access Photonic Integrated Circuit (PIC) assembly & packaging Pilot Line. It combines a highly-interdisciplinary team of Europes leading industrial & research organisations. PIXAPP provides Europes SMEs with a unique one-stop-shop, enabling them to exploit the breakthrough advantages of PIC technologies. PIXAPP bridges the valley of death, providing SMEs with an easy access route to take R&D results from lab to market, giving them a competitive advantage over global competition. Target markets include communications, healthcare & security, which are of great socio-economic importance to Europe. PIXAPPs manufacturing capabilities can support over 120 users per year, across all stages of manufacturing, from prototyping to medium scale manufacture. PIXAPP bridges missing gaps in the value chain, from assembly & packaging, through to equipment optimisation, test and application demonstration. To achieve these ambitious objectives, PIXAPP will; 1) Combine a group of Europes leading industrial & research organisations in an advanced PIC assembly & packaging Pilot Line facility.2) Develop an innovative Pilot Line operational model that coordinates activities between consortium partners & supports easy user access through a single entry point. 3) Establish packaging standards that provide cost-efficient assembly & packaging solutions, enabling transfer to full-scale industrial manufacture. 4) Create the highly-skilled workforce required to manage & operate these industrial manufacturing facilities.5) Develop a business plan to ensure Pilot Line sustainability & a route to industrial manufacturing. PIXAPP will deliver significant impacts to a wide stakeholder group, highlighting how industrial & research sectors can collaborate to address emerging socio-economic challenges.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 34.71M | Year: 2017
The IoF2020 project is dedicated to accelerate adoption of IoT for securing sufficient, safe and healthy food and to strengthen competitiveness of farming and food chains in Europe. It will consolidate Europes leading position in the global IoT industry by fostering a symbiotic ecosystem of farmers, food industry, technology providers and research institutes. The IoF2020 consortium of 73 partners, led by Wageningen UR and other core partners of previous key projects such as FIWARE and IoT-A, will leverage the ecosystem and architecture that was established in those projects. The heart of the project is formed by 19 use cases grouped in 5 trials with end users from the Arable, Dairy, Fruits, Vegetables and Meat verticals and IoT integrators that will demonstrate the business case of innovative IoT solutions for a large number of application areas. A lean multi-actor approach focusing on user acceptability, stakeholder engagement and sustainable business models will boost technology and market readiness levels and bring end user adoption to the next stage. This development will be enhanced by an open IoT architecture and infrastructure of reusable components based on existing standards and a security and privacy framework. Anticipating vast technological developments and emerging challenges for farming and food, the 4-year project stays agile through dynamic budgeting and adaptive decision-making by an implementation board of representatives from key user organizations. A 6 M mid-term open call will allow for testing intermediate results and extending the project with technical solutions and test sites. A coherent dissemination strategy for use case products and project learnings supported by leading user organizations will ensure a high market visibility and an increased learning curve. Thus IoF2020 will pave the way for data-driven farming, autonomous operations, virtual food chains and personalized nutrition for European citizens.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: INFRADEV-04-2016 | Award Amount: 9.95M | Year: 2017
The EOSCpilot project will support the first phase in the development of the European Open Science Cloud (EOSC) as described in the EC Communication on European Cloud Initiatives . It will establish the governance framework for the EOSC and contribute to the development of European open science policy and best practice; It will develop a number of pilots that integrate services and infrastructures to demonstrate interoperability in a number of scientific domains; and It will engage with a broad range of stakeholders, crossing borders and communities, to build the trust and skills required for adoption of an open approach to scientific research . These actions will build on and leverage already available resources and capabilities from research infrastructure and e-infrastructure organisations to maximise their use across the research community. The EOSCpilot project will address some of the key reasons why European research is not yet fully tapping into the potential of data. In particular, it will: reduce fragmentation between data infrastructures by working across scientific and economic domains, countries and governance models, and improve interoperability between data infrastructures by demonstrating how data and resources can be shared even when they are large and complex and in varied formats, In this way, the EOSC pilot project will improve the ability to reuse data resources and provide an important step towards building a dependable open-data research environment where data from publicly funded research is always open and there are clear incentives and rewards for the sharing of data and resources.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: ICT-02-2016 | Award Amount: 9.08M | Year: 2017
The InSCOPE project will set-up an open access pilot line service for Hybrid TOLAE (H-TOLAE) technologies capable of sampling products at TRL6-7. It positions itself in between R&D and industry and deploys a service for validating potential H-TOLAE products. Manufacturing progresses beyond R&D level (TRL5 towards 6) by improving processes, functionality and reliability allowing sampling at high quality and in relevant numbers needed for industrial qualification (TRL 6-7). The applications addressed cover automotive, healthcare, smart packaging and buildings. After InSCOPE, the Pilot line service will remain accessible to interested parties. The pilot line is serviced by top European RTDs with leading technological positions and state of the art equipment in the domain of H-TOLAE. InSCOPE will set up an open access pilot line infrastructure for H-TOLAE technology, which is modular ensuring a comprehensive toolbox of printing, assembly, production integration and process validation distributed over the partners. InSCOPE will ensure interoperability between the differing modules at the partners enabling end-users to combine different processes step from different partners in their process flow. It will accelerate the uptake of H-TOLAE technology by delivering a public handbook describing functionalities, production guidelines and design rules of H-TOLAE, including new opportunities for traditional electronics. Validation of the pilot line service by 4 Showcases and 15 development cases are included within the project. The Showcases consist of H-TOLAE product prototypes at TRL 5 to be matured on functionality and on manufacturability. The showcases will steer the pilot line improvement. They are selected based on their economic impact as well as the technological status of the product and production in Europe. The development cases are devoted to new functionalities enabled by H-TOLAE. They are aimed at SMEs interested in exploring the broad advantages H-TOLAE.