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Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.


Patent
Fountain | Date: 2015-04-15

A device for dispensing individual servings of a cold beverage with Wi-Fi connectivity, either having a refrigeration unit to chill the beverage or a removable pitcher that may be put in a refrigerator. A special disposable beverage cartridge or beverage pouch fits into the holder. This cartridge or pouch may have pressure rupturable seals or diaphragms and contain beverage concentrate. A dispensing mechanism puts pressure on the cartridge or the pouch to break the pressure rupturable seal or diaphragm to discharge the concentrate into a mixing structure. The mixing structure also receives chilled liquid from the refrigeration unit or the pitcher, and ensures that the concentrate mixes with the liquid without contacting the walls of the mixing structure.


Patent
Fountain | Date: 2015-04-08

A cosmetic vacuum bottle includes: a bottle body with a mouth portion, a sealing member, a press member disposed at the mouth portion of the bottle body, and a piston being disposed in the bottle body. A first sealing surface of the sealing member is closely abutted against a first flat surface of the mouth portion to form a first sealing structure, a second sealing surface of the sealing member is abutted against an inner surface of the mouth portion to form a second sealing structure, and a third sealing surface is abutted against a pipe portion of the press member to form a third sealing structure. With the above three sealing structures, vacuum can be created in the bottle body simply by putting the sealing member and the press member to the mouth portion, without having to apply 10 kg torque.


Genetically engineered host animal cells capable of producing glycoproteins having modified glycosylation patterns, e.g., defucosylation and/or monoglycosylation. Such host animal cells can be engineered to express fucosidase, endoglycosidase or both.


Patent
Fountain | Date: 2016-05-11

A device for dispensing individual servings of a cold beverage, either having a refrigeration unit to chill the beverage or a removable pitcher that may be put in a refrigerator. A special disposable beverage cartridge or beverage pouch fits into the holder. This cartridge or pouch may have pressure rupturable seals or diaphragms and contain beverage concentrate. A dispensing mechanism puts pressure on the cartridge or the pouch to break the pressure rupturable seal or diaphragm to discharge the concentrate into a mixing structure. The mixing structure also receives chilled liquid from the refrigeration unit or the pitcher, and ensures that the concentrate mixes with the liquid without contacting the walls of the mixing structure.


Patent
Fountain | Date: 2016-09-09

A home beverage dispensing device for dispensing servings of a beverage, having a vessel for holding a volume of liquid. This vessel may be equipped with a refrigeration unit, or may be comprised of a removable pitcher that may be put in an external refrigerator. This invention is equipped with a radio communications controller to provide for the ability to communicate over radio frequencies such as Wi-Fi and Bluetooth. A special disposable beverage cartridge or beverage pouch fits into the holder. This cartridge or pouch may have pressure rupturable seals or diaphragms and contain beverage concentrate. The mixing structure also receives the optionally chilled liquid from vessel for holding a volume of liquid, and ensures that the concentrate mixes with the liquid without contacting the walls of the mixing structure.


Patent
Fountain | Date: 2015-03-06

A home beverage dispensing device for dispensing servings of a beverage, having a vessel for holding a volume of liquid. This vessel may be equipped with a refrigeration unit, or may be comprised of a removable pitcher that may be put in an external refrigerator. This invention is equipped with a radio communications controller to provide for the ability to communicate over radio frequencies such as Wi-Fi and Bluetooth. A special disposable beverage cartridge or beverage pouch fits into the holder. This cartridge or pouch may have pressure rupturable seals or diaphragms and contain beverage concentrate. The mixing structure also receives the optionally chilled liquid from vessel for holding a volume of liquid, and ensures that the concentrate mixes with the liquid without contacting the walls of the mixing structure.


Patent
Fountain | Date: 2015-12-31

The present disclosure provides antibodies that bind to human interleukin-6 (IL6). The antibodies can modulate IL6 signaling and thus used in treatment or prevention of IL6 associated diseases or disorders, particularly inflammatory disorder, rheumatoid arthritis (RA), angiogenesis, and cancer.


Patent
Fountain | Date: 2015-02-12

A device for dispensing individual servings of a cold beverage, either having a refrigeration unit to chill the beverage or a removable pitcher that may be put in a refrigerator. A special disposable beverage cartridge or beverage pouch fits into the holder. This cartridge or pouch may have pressure rupturable seals or diaphragms and contain beverage concentrate. A dispensing mechanism puts pressure on the cartridge or the pouch to break the pressure rupturable seal or diaphragm to discharge the concentrate into a mixing structure. The mixing structure also receives chilled liquid from the refrigeration unit or the pitcher, and ensures that the concentrate mixes with the liquid without contacting the walls of the mixing structure.


Patent
Fountain | Date: 2016-03-23

A fluid filling station which has a supply tank, filter, transfer pump, a high pressure valve, an optional flow meter, a pressure relief valve, at least one muffler, a filling head, a control module, a purge head, cylinder dispensing mechanism, and its method of use are provided for. This fluid filling station is capable of refilling many types of fluids, but is preferably for the use with carbon dioxide. Additionally, this station is capable of housing and dispensing prefilled refillable fluid containers.

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