ULTRACHIRAL - Ultrasensitive chiral detection by signal-reversing cavity polarimetry: applications to in-situ proteomics, single-molecule chirality, HPLC analysis, medical diagnostics, and atmospheric studies
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: FETOPEN-01-2016-2017 | Award Amount: 4.00M | Year: 2017
Chirality is a fundamental property of life, making chiral sensing and analysis crucial to numerous scientific subfields of biology, chemistry, and medicine, and to the pharmaceutical, chemical, cosmetic, and food industries, constituting a market of 10s of billion , and growing. Despite the tremendous importance of chiral sensing, its application remains very limited, as chiroptical signals are typically very weak, preventing important biological and medical applications. Recently, the project-coordinating FORTH team has introduced a new form of Chiral-Cavity-based Polarimetry (CCP) for chiral sensing, which has three groundbreaking advantages compared to commercial instruments: (a) The chiroptical signals are enhanced by the number of cavity passes (typically ~1000); (b) otherwise limiting birefringent backgrounds are suppressed; (c) rapid signal reversals give absolute polarimetry measurements, not requiring sample removal for a null-sample measurement. Together, these advantages allow improvement in chiral detection sensitivity by 3-6 orders of magnitude (depending on instrument complexity and price). ULTRACHIRAL aims to revolutionize existing applications of chiral sensing, but also to instigate important new domains which require sensitivities beyond current limits, including: (1) measuring protein structure in-situ, in solution, at surfaces, and within cells and membranes, thus realizing the holy-grail of proteomics; (2) coupling to high performance liquid chromatography (HPLC) for chiral identification of the components of complex mixtures, creating new standards for the pharmaceutical and chemical analysis industries; (3) chiral analysis of human bodily fluids as a diagnostic tool in medicine; (4) measurement of single-molecule chirality, by adapting CCP to microresonators, which have already demonstrated single-molecule detection; and (5) real-time chiral monitoring of terpene emissions from individual trees and forests, as a probe of forest ecology.
Agency: European Commission | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2016 | Award Amount: 1.65M | Year: 2017
CyberSure is a programme of collaborations and exchanges between researchers aimed at developing a framework for creating and managing cyber insurance policy for cyber systems. The purpose of creating such policies will be to enhance the trustworthiness of cyber systems and provide a sound basis for liability in cases of security and privacy breaches in them. The framework will be supported by a platform of tools enabling an integrated risk cyber system security risk analysis, certification and cyber insurance, based on the analysis of objective evidence during the operation of such systems. CyberSure will develop its cyber insurance platform at TRL-7 by building upon and integrating state of the art tools, methods and techniques. These will include: (1) the state of the art continuous certification infrastructure (tools) for cloud services developed by the EU project CUMULUS; (2) the risk management tool of NIS enhanced by the NESSOS risk management methodology; and (3) insurance management tools of HELLAS. The development of the CyberSure platform will be driven by certification, risk analysis and cyber insurance scenarios for cyber system pilots providing cloud and e-health services. Through these, CyberSure will address the conditions required for offering effective cyber insurance for interoperable service chains cutting across application domains and jurisdictions.
Agency: European Commission | Branch: H2020 | Program: SGA-RIA | Phase: FETFLAGSHIP | Award Amount: 89.00M | Year: 2016
This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CSA) under the 7th framework program (2013-2016), while this and the following parts are implemented as Core Projects under the Horizon 2020 framework. The mission of the Graphene Flagship is to take graphene and related layered materials from a state of raw potential to a point where they can revolutionise multiple industries. This will bring a new dimension to future technology a faster, thinner, stronger, flexible, and broadband revolution. Our program will put Europe firmly at the heart of the process, with a manifold return on the EU investment, both in terms of technological innovation and economic growth. To realise this vision, we have brought together a larger European consortium with about 150 partners in 23 countries. The partners represent academia, research institutes and industries, which work closely together in 15 technical work packages and five supporting work packages covering the entire value chain from materials to components and systems. As time progresses, the centre of gravity of the Flagship moves towards applications, which is reflected in the increasing importance of the higher - system - levels of the value chain. In this first core project the main focus is on components and initial system level tasks. The first core project is divided into 4 divisions, which in turn comprise 3 to 5 work packages on related topics. A fifth, external division acts as a link to the parts of the Flagship that are funded by the member states and associated countries, or by other funding sources. This creates a collaborative framework for the entire Flagship.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: FETOPEN-01-2016-2017 | Award Amount: 3.79M | Year: 2017
Optoelectronic devices typically operate in the weak coupling regime between light and matter, for example in conventional lasers relying on population inversion to achieve optical gain. Recently there has been a surge of interest in quantum systems operating instead in the strong coupling regime, when the coupling strength of the light-matter interaction is so strong that new states cavity polaritons are created, that are partially light, partially material excitation. In semiconductors, exciton-polaritons have been the most widely studied type of strongly coupled system. Recently a new phenomenon has been realized exploiting intersubband transitions. The resulting excitations are called intersubband polaritons, and they have two remarkable properties: (i) a bosonic character that is maintained up to high carrier densities since they are not restricted by the Mott transition limit; (ii) large Rabi splittings. Although the scientific community has explored the basic science of intersubband polaritons, their potential for future and innovative optoelectronic devices has been entirely untapped. The MIR-BOSE project will realize this potential, and demonstrate disruptive optoelectronic devices operating in the strong coupling regime between light and matter. We will demonstrate the first bosonic lasers operating in the mid-IR and THz ranges of the electromagnetic spectrum. Laser action here does not rely on population inversion, so we will achieve temperature independent operation and high powers. We will demonstrate a new concept of inverse-Q-switching leading to the generation of high power pulses in the mid-IR, overcoming severe bottlenecks in current technology. Finally, we will demonstrate non-classical/quantum light sources and devices, generating squeezed states of light in the mid-IR/THz spectral range for quantum optics. These new sources will have a major impact on several technologies and applications, being advantageous compared to current solutions.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: FETOPEN-01-2016-2017 | Award Amount: 5.75M | Year: 2017
Metasurfaces, thin film planar, artificial structures, have recently enabled the realization of novel electromagnetic (EM) and optical components with engineered functionalities. These include total EM radiation absorption, filtering and steering of light and sound, as well as nano-antennas for sensors and implantable devices. Nonetheless, metasurfaces are presently non-adaptive and non-reusable, restricting their applicability to a single, static functionality per structure (e.g., steering light towards a fixed direction). Moreover, designing a metasurface remains a task for specialized researchers, limiting their accessibility from the broad engineering field. VISORSURF proposes a hardware platform-the HyperSurface-that can host metasurface functionalities described in software. The HyperSurface essentially merges existing metasurfaces with nanonetworks, acting as a reconfigurable metasurface whose properties can be changed via a software interface. This control is achieved by a network of miniaturized controllers, incorporated into the structure of the metasurface. The controllers receive programmatic directives and perform simple alterations on the metasurface structure, adjusting its EM behavior. The required end-functionality is described in well-defined, reusable software modules, adding the potential for hosting multiple functionalities concurrently and adaptively. VISORSURF will study in depth the novel and unexplored theoretical capabilities of the HyperSurface concept. Two experimental prototypes will be implemented: a switch-based fabric array as the control medium; and a Graphene based, making use of its exquisite properties to provide finer control. A real pilot-application will demonstrate the HyperSurface potential to adapt to changes in their environment, to interconnect to smart control loops and make use of Information Technology (IT) programming concepts and algorithms in crafting the EM behavior of materials.
Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 3.51M | Year: 2017
SOLUTION will provide research and training program for 14 early stage researchers (ESR) pursuing their PhD in various disciplines covering the broadly defined area of solid lubricant coatings. The project combines theoretical approaches represented by advanced nanoscale simulations, laboratory design and fabrication of novel solid lubricants supported by simulations, and the up-scaling of promising solutions and their application in selected emerging engineering applications. SOLUTION will link industries from various areas dealing with similar issues through intensive training and knowledge sharing. Three topics driven by industrial partners have been selected to demonstrate the added value of simultaneous development and training. The use of modern solid lubricants underlines the transformation of industry towards smart design, which is based on predictive models and cross-communication throughout the entire production chain. Fellows supported by the project will have a unique opportunity to gain competence ranging from simulation, characterization and processing, to industrial processes and entrepreneurship. Highly individualized multidisciplinary training reflecting actual market needs, together with scientific excellence, will generate an open-mind generation able to harvest multidisciplinary knowledge and to successfully face challenges represented by the design of competitive solid lubricants.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: ICT-06-2016 | Award Amount: 4.17M | Year: 2017
Unicorn aims to simplify the design, deployment and management of secure and elastic by design- multi-cloud services. This will be achieved by a) development and design libraries that will provide security enforcement mechanisms, data privacy restrictions, monitoring metric collection and resource management; b) enabling continuous orchestration and automatic optimization of portable and dynamic cloud services running on virtual instances or micro-execution containers for increased security, data protection privacy and vast resource (de)-allocation. Towards this end, and building upon this umbrella concept, the Unicorn vision can be considered two-fold: to enable software developers to design and develop secure and elastic applications and to increase the awareness of all stakeholders, in particular SMEs and Startups. Unicorn will reduce software release time and provide a powerful tool for SMEs to improve software design and continuous productivity enhancement. The innovation activities in the Unicorn project will be based upon existing solutions and developments to the largest possible extent, and build upon the S&T results of European RIA projects including CELAR, PaaSport, PaaSword and ARCADIA.