Foshan Second Peoples Hospital

Foshan, China

Foshan Second Peoples Hospital

Foshan, China
SEARCH FILTERS
Time filter
Source Type

Ma H.-Z.,Foshan Second Peoples Hospital | Tang Y.-Z.,Foshan Second Peoples Hospital | Zhou H.-S.,Foshan Second Peoples Hospital | Yan S.-G.,Foshan Second Peoples Hospital
International Eye Science | Year: 2017

AIM: To study the application of intravitreal injection of anti-vascular endothelial growth factor (VEGF) inpatients with fundus neovascularization disease in No. 2 Foshan People's Hospital between 2013 to 2015. METHODS: Retrospective analysis of inpatients of Foshan Second People's Hospital from January 2013 to December 2015, searched the inpatient management system with the term "intravitreal injection", excluded patients with intravitreal injection of TA and antibiotics, and queried the diseases involved. Then summarized the amount of inpatients of each disease as comparison. RESULTS: Totally 239 eyes underwent injection in 3 a. The proportion of male and female was even. No statistical difference among the youth, the middle age and the old group. The amount of injections was increased year by year. The main diseases underwent anti-VEGF injection was retinal vein occlusion (RVO), choroidal neovascularization retinopathy (CNV), diabetic retinopathy (DR) and polypoidal choroidal vasculopathy (PCV). Anti-VEGF injection ratio (injection/total) of the four diseases in the same year and each disease of different year were significantly statistic different. Among the four main disease, anti-VEGF injection was the most accepted in CNV patients, and anti-VEGF injection ratio was the most improved in PCV patients. CONCLUSION: Anti-VEGF intravitreal injection as a new treatment for fundus neovascular diseases was increasingly accepted by patients. Copyright 2017 by the IJO Press.


Miao J.,Guangzhou University of Chinese Medicine | Miao J.,Foshan Hospital of Traditional Chinese Medicine | Luo Y.,Guangzhou University of Chinese Medicine | Zhou H.,Foshan Hospital of Traditional Chinese Medicine | And 10 more authors.
International Journal of Clinical and Experimental Medicine | Year: 2017

Purpose: The purpose of this meta-analysis was to determine whether plating or intramedullary nailing (IMN) for adult diaphyseal both-bone forearm fractures (BBFF) provides better clinical outcomes. Materials and methods: MEDLINE, EMBASE, Google Scholar and The Cochrane Library were comprehensively searched until July 31, 2016. Both retrospective study and prospective trails about comparison of dual IMN or hybrid fixation versus dual plating fixation in the treatment of adult diaphyseal BBFF were included. Using RevMan5.3 software, data of functional recovery, the union time, operating time and complication was extracted for meta-analysis. Results: The pooled analysis showed similar results in the union time, functional recovery and the rates of complications, but showed a significant difference in operating time. Conclusions: This meta-analysis demonstrates similar radiographic outcomes, functional outcomes and complications in the treatment of adult diaphyseal BBFF with the comparison between plates and IMN. IMN fixation for these fractures seems to be an alternative and effective treatment with shorter operating times and minimal invasion. © 2017, E-Century Publishing Corporation. All rights reserved.


Liang J.,Southern Medical University | Liang J.,Foshan Second Peoples Hospital | Bai S.,Foshan Second Peoples Hospital | Su L.,Southern Medical University | And 4 more authors.
Molecular Medicine Reports | Year: 2015

The objective of the present study was to analyze the differences in the plasma microRNA (miRNA) expression profiles between patients with myocardial infarction (MI) (with or without heart failure) and individuals in a normal control group using an miRNA array. Specific miRNAs were selected to explore novel circulating markers for MI and heart failure. A total of 15 patients with heart failure and 10 patients without heart failure following acute MI (AMI) were recruited as the AMI with heart failure (AMHF) and with no heart failure (AMNHF) groups, respectively. In addition, 10 patients with an older (≥1 year) MI with heart failure were selected as the old MI and heart failure (OMHF) group. Finally, 10 patients with normal coronary angiograms were recruited as the control (N) group. The plasma of peripheral venous blood was collected for miRNA array detection. In the AMHF group, the expression of 17 miRNAs was upregulated and the expression of 21 miRNAs was downregulated by >1.5-fold compared with that in the AMNHF group. Compared with the N group, the expression of miRNAs in the AMNHF group was upregulated in 38 and downregulated in 48 cases by >1.5-fold. Compared with the OMHF group, 13 miRNAs were upregulated and 43 were downregulated by >1.5-fold in the AMHF group. Significant differences in the miRNA expression profiles were observed between patients with different stages of heart failure following MI and individuals in the normal control group. These differences were determined using miRNA array analysis methods based on the peripheral blood plasma. Thus, the specific miRNAs identified in this study may be novel circulating markers for MI and heart failure.


PubMed | Southern Medical University and Foshan Second Peoples Hospital
Type: Journal Article | Journal: Molecular medicine reports | Year: 2015

The objective of the present study was to analyze the differences in the plasma microRNA (miRNA) expression profiles between patients with myocardial infarction (MI) (with or without heart failure) and individuals in a normal control group using an miRNA array. Specific miRNAs were selected to explore novel circulating markers for MI and heart failure. A total of 15 patients with heart failure and 10 patients without heart failure following acute MI (AMI) were recruited as the AMI with heart failure (AMHF) and with no heart failure (AMNHF) groups, respectively. In addition, 10 patients with an older ( 1 year) MI with heart failure were selected as the old MI and heart failure (OMHF) group. Finally, 10 patients with normal coronary angiograms were recruited as the control (N) group. The plasma of peripheral venous blood was collected for miRNA array detection. In the AMHF group, the expression of 17 miRNAs was upregulated and the expression of 21 miRNAs was downregulated by >1.5-fold compared with that in the AMNHF group. Compared with the N group, the expression of miRNAs in the AMNHF group was upregulated in 38 and downregulated in 48 cases by >1.5-fold. Compared with the OMHF group, 13 miRNAs were upregulated and 43 were downregulated by >1.5-fold in the AMHF group. Significant differences in the miRNA expression profiles were observed between patients with different stages of heart failure following MI and individuals in the normal control group. These differences were determined using miRNA array analysis methods based on the peripheral blood plasma. Thus, the specific miRNAs identified in this study may be novel circulating markers for MI and heart failure.


Huang Y.-J.,Foshan Second Peoples Hospital | Luo S.-K.,Foshan Second Peoples Hospital | Ling P.,Foshan Second Peoples Hospital | Lu Q.,Foshan Second Peoples Hospital | Chen R.,Foshan Second Peoples Hospital
International Eye Science | Year: 2012

AIM: To evaluate long-term visual performance after Tetraflex accommodative intraocular lens(AIOL) implantation by measuring the visual acuity, pseudophakic accommodation, visual symptoms. METHODS: Case-control study. Forty-three consecutive age-related cataract patients (49 eyes) were enrolled and received routine cataract phacoemulsification with IOL implantation surgery. All the cases were randomly divided into 2 groups: Tetraflex group(21 cases 25 eyes), which received Tetraflex AIOL ( and SA60AT group(22 cases 24 eyes), which received Acrysof SA60AT IOL (3, 6, and 24 months postoperatively, the uncorrected and best-corrected distance visual acuity(UCDVA and BCDVA), uncorrected and best distance-corrected near visual acuity(UCNVA and BCNVA), pseudophakic accommodation, diopter and complications were studied between the two groups. Questionnaire of visual function was used to investigate the visual symptoms. The indexes were analyzed by SPSS13.0 statistics software. RESULTS: There were no statistically significant differences in UCDVA and BCDVA between the two groups 3, 6, and 24 months postoperatively (P>0.05); while there were statistically significant differences in UCNVA and BCNVA (P<0.05 ). Minus lens method was applied to evaluate the pseudophakic accommodation: after 3 months, Tetraflex group was 3.56±1.20D, SA60AT group was -0.25±0.20D; after 6 months, Tetraflex group 3.08±1.30D, SA60AT group -0.20±0.18D; 24 months later, Tetraflex group 2.85±1.22D, SA60AT group -0.15±0.16D. Tetraflex AIOL lens provided excellent pseudophakic accommodation than monofocal IOL(P<0.05), and also in close reading and satisfaction of the curative effects (P<0.05). CONCLUSION: Compared with monofocal IOL, Tetraflex AIOL provides age-related cataract patients with good distance and near vision, as well as pseudophakic accommodation. Although pseudophakic accommodation of Tetraflex AIOL decreases in long-term, it gradually becomes stable.


Xie J.-Y.,Foshan Second Peoples Hospital | Lu H.-Q.,Foshan Second Peoples Hospital | Luo S.-K.,Foshan Second Peoples Hospital | Yan S.-G.,Foshan Second Peoples Hospital
International Eye Science | Year: 2013

AIM: To survey the application of dynamic contour tonometer(DCT) in normal tension glaucoma(NTG) patients, primary open angle glaucoma(POAG) patients and healthy controls. And to analyze the factors that influence the ocular pulse amplitude (OPA). METHODS: In this case-control study, twenty NTG patients, twenty-one POAG patients and twenty health people were included in the study. Intraocular pressure (IOP) was measured in each group with GAT and DCT. Correlation between the value of IOP measured with DCT and GAT were analyzed. Meanwhile, central corneal thickness(CCT), axial length(AL), systolic blood pressure(SBP), diastolic blood pressure(DBP) and heart rate(HR) were also measured to evaluate the influencing factor of OPA. RESULTS: There were significant statistical differences of IOP, OPA, SBP and DBP among NTG patients, POAG patients and healthy controls. There were no significant statistical differences of CCT, AL and HR among those subjects. The OPA were 1.7±0.9mmHg in NTG patients, 2.8±0.7mmHg in POAG patients and 2.4±0.6mmHg in normal controls. There was no significant statistical difference of OPA between POAG patients and normal controls(P=0.502), whereas significant statistical difference of OPA between POAG patients and NTG patients (P=0.001) was observed. Significant statistical difference of OPA between NTG patients and normal controls(P=0.005) was detected. The results of Pearson correlation analysis showed that there was significant correlation between OPA with AL, SBP and DBP(P<0.05). No significant correlation was found between OPA with IOP, HR and CCT(P>0.05). CONCLUSION: There are differences of OPA among NTG patients, PAOG patients and normal controls. And OPA is influenced by AL, SBP and DBP.


Luo S.,Foshan Second Peoples Hospital | Lin Z.,Foshan Second Peoples Hospital
Eye science | Year: 2012

PURPOSE: To investigate the stereopsis after single focus intraocular lens (SIOL) implantation in patients aged <40 years with unilateral cataract.METHODS: In total, 36 patients (36 eyes) were divided into emmetropia and myopia groups. Twenty seven subjects with good uncorrected distance visual acuity (UCDVA) after surgery were enrolled in the emmetropia group. The myopia group consisted of 9 subjects whose one eye had mild myopia postoperatively and the other was emmetropic or myopic. Visual acuity, distance and near stereoacuity were measured post-operatively.RESULTS: In the emmetropia group, uncorrected near visual acuity (UCNVA) did not differ significantly between eyes (t=1.87, P>0.05). The LogMAR UCNVA of the operated and fellow eyes were (0.71±0.12) and (-0.05±0.07, t = 28.4, P<0.001) respectively. Distance stereoacuity was 60"; the near stereoacuity with uncorrected visual acuity and BCNVA in the operated eyes were 200" and 30" respectively (Z=-4.121, P<0.001). In the myopia group, the BCDVA did not differ significantly between the operated and fellow eyes (t =-0.636, P>0.05). The UCNVA of the operated eyes (0.18±0.12) was significantly better compared with that of the fellow eyes (-0.04±0.10, t = 4.2252, P<0.001). The distance stereoacuity with uncorrected visual acuity and BCDVA in the operated eyes were 200" and 60" respectively (Z =-2.371, P<0.05). The near stereoacuity with uncorrected visual acuity was 50".CONCLUSION: For patients with unilateral cataract aged <40 years, stereopsis is closely associated with refractive status after IOL implantation. Near stereoacuity in emmetropic eyes can be improved with refraction, and that in mildly myopic eyes can be enhanced by leaving myopia uncorrected.


Xie J.-Y.,Foshan Second Peoples Hospital | Yan S.-G.,Foshan Second Peoples Hospital | Lu H.-Q.,Foshan Second Peoples Hospital | Luo S.-K.,Foshan Second Peoples Hospital
International Eye Science | Year: 2013

AIM: To obverse visual acuity, pseudophakic accommodation, visual performance after implantation of the Tetraflex accommodative intraocular lens (IOL) in patients with age-related cataract. METHODS: Case -control study. Forty-eight patients (seventy-two eyes) with age-related cataract received phacoemulsification and implantation of artificial intraocular lens in our department during March 2010 to December 2012. The patients were randomly divided into 2 groups: Tetraflex group( 23 cases 35 eyes) and SA60AT group (25 cases 37 eyes). All patients were assessed for visual acuity, accommodation amplitude and contrast sensitivity visual acuity in 1, 3 and 6mo after the surgery. The indexes were analyzed by SPSS 13.0 statistics software. RESULTS: There were no statistically significant differences in uncorrected distance visual acuity (UCDVA) and best-corrected distance visual acuity(BCDVA) between the two groups(P>0.05); while there were statistically significant differences in uncorrected near visual acuity (UCNVA) and distance-corrected near vision acuity (DCNVA)(P<0.05). There was no significant difference of contrast sensitivity between the 2 groups (P>0.05). The Tetraflex group has best accommodative amplitude than the SA60AT group(P<0.05), and there was no significant difference of contrast sensitivity between the 2 groups (P>0.05). The Tetraflex group had higher rate of spectable independence than the SA60AT group (82.9% vs 16.2%) (P<0.05). CONCLUSION: Tetraflex provides an excellent distance and near visual acuity, good amplitude of accommodation and decrease the dependence of spectacle, and improve the visual performance. But its long-term effect remains to be observed. Copyright 2013 by the IJO Press.


Shangguan H.,Foshan Second Peoples Hospital | Wang B.-Z.,Foshan Second Peoples Hospital
Journal of Leukemia and Lymphoma | Year: 2010

Objective To evaluate the efficacy and safety of valproic acid combined with all-trans retinoic acid(ATRA) in the treatment of myelodysplastic syndrome. Methods Twenty-two patients with MDS consisting of 4 RA, 1 RARS, 10 RCMD, 1 RCMD-RS, 3 RAEB-1 and 3 RAEB-2 were analyzed. The initial dose of valproic acid was 0.6 g/d, then increased to 1.2 g/d after one week; all-trans retinoic acid was administered at 30 mg/d every other week after taken VPA one week later. All patients maintained treatment for 3 months unless severe side effect was found or disease progression. Bone marrow examination was taken every 4 weeks. Results The response rate was 27.3% (6 cases) according to International Working Group (IWG) criteria, no patient achieved completely remission(CR), 2 cases achieved partial remission(PR), 4 case achieved hematologic improvement (HI), 9 cases was stable and 7 cases was failure. Most of these cases had slight adverse events and could be tolerated. Conclusion Valproic acid combined with all-trans retinoic acid in the treatment of patients with mye1odysplastic syndrome was efficient and side effect was tolerable.


PubMed | Foshan Second Peoples Hospital
Type: Journal Article | Journal: Eye science | Year: 2012

To investigate the stereopsis after single focus intraocular lens (SIOL) implantation in patients aged <40 years with unilateral cataract.In total, 36 patients (36 eyes) were divided into emmetropia and myopia groups. Twenty seven subjects with good uncorrected distance visual acuity (UCDVA) after surgery were enrolled in the emmetropia group. The myopia group consisted of 9 subjects whose one eye had mild myopia postoperatively and the other was emmetropic or myopic. Visual acuity, distance and near stereoacuity were measured post-operatively.In the emmetropia group, uncorrected near visual acuity (UCNVA) did not differ significantly between eyes (t=1.87, P>0.05). The LogMAR UCNVA of the operated and fellow eyes were (0.710.12) and (-0.050.07, t = 28.4, P<0.001) respectively. Distance stereoacuity was 60; the near stereoacuity with uncorrected visual acuity and BCNVA in the operated eyes were 200 and 30 respectively (Z=4.121, P<0.001). In the myopia group, the BCDVA did not differ significantly between the operated and fellow eyes (t =-0.636, P>0.05). The UCNVA of the operated eyes (0.180.12) was significantly better compared with that of the fellow eyes (-0.040.10, t = 4.2252, P<0.001). The distance stereoacuity with uncorrected visual acuity and BCDVA in the operated eyes were 200 and 60 respectively (Z =-2.371, P<0.05). The near stereoacuity with uncorrected visual acuity was 50.For patients with unilateral cataract aged <40 years, stereopsis is closely associated with refractive status after IOL implantation. Near stereoacuity in emmetropic eyes can be improved with refraction, and that in mildly myopic eyes can be enhanced by leaving myopia uncorrected.

Loading Foshan Second Peoples Hospital collaborators
Loading Foshan Second Peoples Hospital collaborators