Cambridge, ME, United States
Cambridge, ME, United States

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Patent
FORMA Therapeutics | Date: 2016-09-02

The present invention is directed to compounds of Formula I:


Patent
FORMA Therapeutics | Date: 2016-05-12

The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R^(1), R^(2), R^(5), and R^(8 )are as described herein.


Patent
FORMA Therapeutics | Date: 2016-05-12

The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R_(1), R_(2), R_(4 )and R_(7 )are defined herein.


Patent
FORMA Therapeutics | Date: 2016-02-02

The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I: where R, L, X^(1), X^(2), X^(3), X^(4), Y^(1), Y^(2), Y^(3), and Y^(4 )are described herein.


Patent
FORMA Therapeutics | Date: 2016-02-02

The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formula I: where R, L, X^(1), X^(2), X^(3), X^(4), Y^(1), Y^(2), Y^(3), and Y^(4 )are described herein.


Patent
FORMA Therapeutics | Date: 2016-02-02

The present invention relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with HDAC6, having a Formulae I or Formula II: where R, L, X^(1), X^(2), X^(3), X^(4), X^(5), Y^(1), Y^(2), Y^(3), and Y^(4 )are described herein.


Patent
FORMA Therapeutics | Date: 2016-02-02

The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I: where R, L, X^(1), X^(2), X^(3), X^(4), Y^(1), Y^(2), Y^(3), and Y^(4 )are described herein.


Patent
FORMA Therapeutics | Date: 2016-02-02

The present disclosure relates to inhibitors of zinc-dependent histone deacetylases (HDACs) useful in the treatment of diseases or disorders associated with an HDAC, e.g., HDAC6, having a Formula I: where R, L, X^(1), X^(2), X^(3), X^(4), Y^(1), Y^(2), Y^(3), and Y^(4 )are described herein.


Patent
FORMA Therapeutics | Date: 2016-05-12

The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: wherein W, X, Y, Z, R^(1), R^(2), R^(5), and R^(8 )are as described herein.


Patent
FORMA Therapeutics | Date: 2016-05-12

The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R_(1), R_(2), R_(4 )and R_(7 )are defined herein.

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