Forensic Medical Service of Athens

Athens, Greece

Forensic Medical Service of Athens

Athens, Greece

Time filter

Source Type

Gavrielatos G.,Herz Zentrum | Nerantzis C.E.,Forensic Medical Service of Athens
Hellenic Journal of Cardiology | Year: 2011

The incidence of sinoatrial artery variants and their significance have been repeatedly reported in the literature. Herein we describe a rare post mortem angiographic finding which concerns a unique and previously unreported case where the sinus node artery had an abnormal origin from the proximal conus artery. Although it was asymptomatic, any possible involvement with invasive or surgical procedures and its clinical consequences should be considered.


Nerantzis C.E.,Forensic Medical Service of Athens | Karakoukis N.G.,Forensic Medical Service of Athens | Di Lernia G.C.,Forensic Medical Service of Athens | Bouzianis S.G.,Forensic Medical Service of Athens | And 2 more authors.
Anatomical Science International | Year: 2016

We describe histologically cases of patients between 31 and 60 years of age who had fibromuscular dysplasia (FMD) in the tunica media (TM) of the left ventricle papillary muscles (PM) arteries. We also compared them with our previous findings in subjects younger than 30 years of age. We examined histologically samples taken from the tip of the anterior PM of the left ventricle in 200 healthy male hearts. In 33 cases (16.5 %), FMD was in the TM. We divided these cases into three subgroups (A, B, C) based on the degree of replacement of smooth muscle cells by fibrous tissue, and thus identified 17, 11 and 5 cases, respectively. Until the age of 41, the typical lesions were often localized within the TM. Beyond that age, the fibrous tissue increased in the TM wall and in the surrounding area of the vessels, causing dysfunction of the PM. Degenerative lesions, as well as inflammatory infiltration, were found after the age of 53. The findings of this study will be useful to cardiologists and cardiac surgeons, in pointing out that, after the age of 44 years old, some PM and their supporting valves may present a degree of dysfunction. © 2016 Japanese Association of Anatomists


Nerantzis C.E.,Forensic Medical Service of Athens | Koulouris S.N.,Evagelismos Hospital | Marianou S.K.,Forensic Medical Service of Athens | Pastromas S.C.,Evagelismos Hospital | And 2 more authors.
Journal of Forensic Sciences | Year: 2011

Sudden unexpected death is frequent in street heroin addicts. We conducted a histologic study of the sinus node (SN) to offer some evidence about the possible arrhythmogenic cause of death. Postmortem coronary angiography and microscopic examination of the SN and the perinodal area were performed in 50 heroin addicts (group 1) and in 50 nonaddicts (group 2), all men (16-40years old). In heroin addicts, fatty and/or fibrous tissue replaced SN tissue in 21 cases (42%). Perinodal infiltration was found in 15 cases (30%). Fibromuscular dysplasia in branches of the sinus node artery (SNA) was found in eight cases (16%). Inflammation with focal and/or diffuse concentration of round cells was detected in the SN in 22 cases (44%). Old mural thrombi were also found in 13 cases (26%). The histologic changes in the SN and perinodal area offer an explanation about the possible mechanism of arrhythmia and sudden death in this population. © 2011 American Academy of Forensic Sciences.


PubMed | Eyagkelismos Hospital, National and Kapodistrian University of Athens and Forensic Medical Service of Athens
Type: | Journal: Anatomical science international | Year: 2016

We describe histologically cases of patients between 31 and 60years of age who had fibromuscular dysplasia (FMD) in the tunica media (TM) of the left ventricle papillary muscles (PM) arteries. We also compared them with our previous findings in subjects younger than 30years of age. We examined histologically samples taken from the tip of the anterior PM of the left ventricle in 200 healthy male hearts. In 33 cases (16.5%), FMD was in the TM. We divided these cases into three subgroups (A, B, C) based on the degree of replacement of smooth muscle cells by fibrous tissue, and thus identified 17, 11 and 5 cases, respectively. Until the age of 41, the typical lesions were often localized within the TM. Beyond that age, the fibrous tissue increased in the TM wall and in the surrounding area of the vessels, causing dysfunction of the PM. Degenerative lesions, as well as inflammatory infiltration, were found after the age of 53. The findings of this study will be useful to cardiologists and cardiac surgeons, in pointing out that, after the age of 44years old, some PM and their supporting valves may present a degree of dysfunction.


Nerantzis C.E.,Forensic Medical Service of Athens | Koulouris S.,Evagelismos General Hospital | Pastromas S.,Evagelismos General Hospital
Surgical and Radiologic Anatomy | Year: 2011

Purpose: The purpose of the study was to examine the anatomical variations of the sinus node artery (SNA). Methods: Gross anatomical examination, angiographic evaluation and if necessary dissection were performed in 200 human hearts derived from victims of various accidents. Results: The SNA was a branch of the right coronary artery in 118 [59%] cases, the left circumflex in 78 [39%] cases and both coronary arteries in 4 [2%] cases. In one subject, the SNA was found to arise from the distal part of the right coronary artery. Conclusions: In our case, the sinus node was perfused by a SNA arising from the mid-posterior segment of the right coronary artery. Knowledge of this anatomical variation is useful for anatomists and of clinical significance for the interventional cardiologists and mainly for the cardiac surgeons in planning the surgical procedures. © 2010 Springer-Verlag.


Nerantzis C.E.,Forensic Medical Service of Athens | Couvaris C.M.,Forensic Medical Service of Athens | Pastromas S.C.,Evagelismos Hospital | Marianou S.K.,Forensic Medical Service of Athens | And 2 more authors.
Journal of Forensic Sciences | Year: 2013

A study of the atrioventricular (AV) conducting tissue was considered necessary for the examination of probable histologic changes that could justify the arrhythmias observed in street-heroin addicts. Postmortem coronary angiography and microscopic examination were performed in 50 heroin addicts (group A) and in 50 nonaddicts (group B), all male 16-40 years old. In group A, fatty and/or fibrous tissue replaced the AV node in 50% of cases while in group B in 14%. The main bundle was replaced by fatty and/or fibrous tissue in 44% in group A cases and 10% in group B. Intimal proliferation and fibromuscular dysplasia of the AV arteries in group A were correspondingly 26% and 14% and in group B 6% and 2%. Inflammation with focal and/or diffuse concentration of round cells of the AV node was detected in 54% in group A. These findings could explain a possible arrhythmia mechanism in this population. © 2012 American Academy of Forensic Sciences.


Nerantzis C.E.,Forensic Medical Service of Athens | Anninos H.,Forensic Medical Service of Athens | Koutsaftis P.N.,Forensic Medical Service of Athens
Surgical and Radiologic Anatomy | Year: 2010

Purpose The purpose of the study was to examine the anatomical variations in the blood supply to the sinus node. Methods Gross anatomical examination and angiographic evaluation were performed in 400 human hearts derived from victims of various accidents. Results The sinus node artery was a branch of the right coronary artery in 245 cases, the left circumXex in 147 cases, and both coronary arteries in 8 cases. In one subject, two sinus node arteries were found to arise from the left circumXex artery, a Wnding never reported before. Conclusions Anatomic and postmortem angiographic Wndings of a previously unreported case where the sinus node is perfused by two sinus node arteries originating from the left circumXex coronary artery are demonstrated. Knowledge of this anatomical variation is useful for anatomists and of clinical signiWcance for the interventional cardiologists and mainly for the cardiac surgeons in planning the surgical procedures. © Springer-Verlag 2010.


PubMed | Forensic Medical Service of Athens
Type: | Journal: Journal of forensic sciences | Year: 2013

A study of the atrioventricular (AV) conducting tissue was considered necessary for the examination of probable histologic changes that could justify the arrhythmias observed in street-heroin addicts. Postmortem coronary angiography and microscopic examination were performed in 50 heroin addicts (group A) and in 50 nonaddicts (group B), all male 16-40 years old. In group A, fatty and/or fibrous tissue replaced the AV node in 50% of cases while in group B in 14%. The main bundle was replaced by fatty and/or fibrous tissue in 44% in group A cases and 10% in group B. Intimal proliferation and fibromuscular dysplasia of the AV arteries in group A were correspondingly 26% and 14% and in group B 6% and 2%. Inflammation with focal and/or diffuse concentration of round cells of the AV node was detected in 54% in group A. These findings could explain a possible arrhythmia mechanism in this population.


PubMed | Forensic Medical Service of Athens
Type: Journal Article | Journal: Surgical and radiologic anatomy : SRA | Year: 2010

The purpose of the study was to examine the anatomical variations in the blood supply to the sinus node.Gross anatomical examination and angiographic evaluation were performed in 400 human hearts derived from victims of various accidents.The sinus node artery was a branch of the right coronary artery in 245 cases, the left circumflex in 147 cases, and both coronary arteries in 8 cases. In one subject, two sinus node arteries were found to arise from the left circumflex artery, a finding never reported before.Anatomic and postmortem angiographic findings of a previously unreported case where the sinus node is perfused by two sinus node arteries originating from the left circumflex coronary artery are demonstrated. Knowledge of this anatomical variation is useful for anatomists and of clinical significance for the interventional cardiologists and mainly for the cardiac surgeons in planning the surgical procedures.


PubMed | Forensic Medical Service of Athens
Type: Journal Article | Journal: Surgical and radiologic anatomy : SRA | Year: 2011

The purpose of the study was to examine the anatomical variations of the sinus node artery (SNA).Gross anatomical examination, angiographic evaluation and if necessary dissection were performed in 200 human hearts derived from victims of various accidents.The SNA was a branch of the right coronary artery in 118 [59%] cases, the left circumflex in 78 [39%] cases and both coronary arteries in 4 [2%] cases. In one subject, the SNA was found to arise from the distal part of the right coronary artery.In our case, the sinus node was perfused by a SNA arising from the mid-posterior segment of the right coronary artery. Knowledge of this anatomical variation is useful for anatomists and of clinical significance for the interventional cardiologists and mainly for the cardiac surgeons in planning the surgical procedures.

Loading Forensic Medical Service of Athens collaborators
Loading Forensic Medical Service of Athens collaborators