Patterson R.,College of Charleston |
Mabe P.,College of Charleston |
Mitchell E.N.,Forensic Laboratory |
Cory W.,College of Charleston
Forensic Science International | Year: 2012
For street samples suspected of containing the phosphodiesterase-5 inhibitors sildenafil (Viagra®) and/or vardenafil (Levitra®), including powders or adulterated herbal supplements, a chemical analysis is needed to provide confirmatory identification of these illegally procured substances. Sildenafil and vardenafil are structurally similar and it is difficult to differentiate between them, as previous mass spectrometric studies have shown the two drugs to produce similar fragmentation patterns. The use of tandem mass spectrometry can produce confirmatory data, but the technique requires a high level of technical expertise. We have developed an electrospray ionization-liquid chromatography-mass spectrometry (ESI-LC-MS) method that allows differentiation between these two structurally similar molecules via in-source fragmentation in combination with an ion trap mass spectrometer. A very stable gas phase ion is formed during in-source fragmentation of vardenafil; the combination of the stability of this ion and the longer residence time for the ion in the ion trap results in a very strong signal. This feature results in a method that can provide clear differentiation between sildenafil and vardenafil while at the same time requiring less expertise from the routine analyst to confirm the presence or absence of the two compounds. © 2012 Elsevier Ireland Ltd.
Paakkonen R.,Finnish Institute of Occupational Health |
Jussila J.,Forensic Laboratory
Applied Acoustics | Year: 2011
Shootings at test shooting sites indoors can cause a risk of hearing loss for the workers at the site. The noise can also disturb other persons working in nearby rooms in the same building. A simple suppressor was constructed from a ventilation sound absorber. Sound level meters were installed near the shooter, to his side and in front of him, and in two nearby rooms. The suppressor solution attenuated the peak noise level to the side by 14-18 dB. Near the ear of the shooter, the amplification was 1-4 dB due to reflections. Therefore, a suppressor should have an adjustment mat between the muzzle of the weapon and the suppressor that would isolate sound from the muzzle backwards. In front of the shooter, the peak levels were attenuated by 0-3 dB due to the suppressor system. The suppressor system attenuated noise best to the side. The opening between the muzzle and the suppressor system caused the attenuation at the back of the weapon to be modest. In front, the bullet flight noise remained, and as a result there was no significant noise reduction in this direction. More noise control work is still needed, and one possibility for improvement would be a better enclosure of the imminent shooting area. © 2011 Elsevier Ltd. All rights reserved.
Erden S.,Forensic Laboratory |
Durmus Z.,Ankara University |
Kilic E.,Ankara University
Electroanalysis | Year: 2011
Differential pulse cathodic adsorptive stripping (DPCAdSV) and square wave cathodic adsorptive stripping (SWCAdSV) voltammetric methods were developed for the determination of antimony and lead in gunshot residues. Linear working ranges for DPCAdSV and SWCAdSV methods were (2.0×10-9-5.0×10-7)M and (2.0×10-9-7.0×10-7)M for antimony and 2.0×10-9-3.0×10-7M (both methods) for lead. The detection of antimony limits were found to be 1.3×10-9M for DPCAdSV and 7.3×10-10M for SWCAdSV while the corresponding values for lead were 3.0×10-9M and 5.8×10-10M. Antimony and lead contents obtained by these methods in gunshot residues are in good agreement with those obtained by graphite furnace atomic absorption spectrometric method within a confidence limit of 95%. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
News Article | March 1, 2017
Applied Forensics, headquartered in New York, announces the opening of an office in Tampa, Florida to serve the Tampa metropolitan area. Applied Forensics has offices in New York, Washington DC, Boston MA and Farmington, CT. The company has hired Gerhard W Wendt as a Forensic Document Examiner in the Tampa office. He joins a staff of highly qualified forensic document examiners and analysts located in the New York, Boston, Washington DC and Connecticut offices. Wendt previously worked as a Forensic Document Examiner in a major metropolitan government laboratory in the Mid-Atlantic. Wendt will bring an extensive wealth of Forensic Science knowledge to his work at Applied Forensics. He has attended numerous seminars and lectured in the field of Forensic Document Examination. He has testified numerous times in the field. Applied Forensics provides their services in all areas of Questioned Documents and Handwriting Examination in cases that are criminal, civil or administrative in nature to an impressive group of local, regional and national clients. Applied Forensics uses the latest instrumentation and analytical tools to provide the most complete and thorough examination of submitted signatures. For more information about Applied Forensics and Gerhard W. Wendt, please visit their website http://www.appliedforensics.com. Applied Forensics LLC is a 21st century Forensic Laboratory specializing in expert examination of handwriting forgery, signatures, altered documents, anonymous letters and the analysis of many other disputed or questioned documents.
Abu Shawish H.M.,University of Palestine |
Abed Almonem K.I.,Minesty of Education and Higher Education |
Saadeh S.M.,Islamic University of Gaza |
Al-Lham W.S.,Forensic Laboratory
Measurement: Journal of the International Measurement Confederation | Year: 2016
A modified carbon paste electrode for haloperidol drug based on haloperidol-phosphomolybdate (HP-PM) as an ion-exchanger dissolved in plasticizer DBP and its potentiometric characteristics were discussed. The electrode exhibited a good Nernstian slope of 56.9 ± 0.3 mV/decade with a linear concentration range from 3.2 × 10-6 to 1.0 × 10-2 M for the haloperidol ion. The limit of detection (LOD) was 1.5 × 10-6 M. It had response time of 5-8 seconds (s), useable in pH range of 6.2-8.6 and temperature of 20-60°C. The electrode shows clear discrimination of haloperidol drug from several inorganic ions, sugars and some common drug excipients. The sensor was applied for determination of haloperidol drug in urine and in pharmaceutical formulations using potentiometric determination, standard addition and the calibration curve methods. The results are satisfactory with excellent percentage recovery comparable or better than those obtained by other routine methods. © 2015 Elsevier Ltd.
Broseus J.,University of Lausanne |
Huhtala S.,Forensic Laboratory |
Esseiva P.,University of Lausanne
Forensic Science International | Year: 2015
For the first time in Finland, the chemical profiling of cocaine specimens was performed at the National Bureau of Investigation (NBI). The main goals were to determine the chemical composition of cocaine specimens sold in the Finnish market and to study the distribution networks of cocaine in order to provide intelligence related to its trafficking. An analytical methodology enabling through one single GC-MS injection the determination of the added cutting agents (adulterants and diluents), the cocaine purity and the chemical profile (based on the major and minor alkaloids) for each specimen was thus implemented and validated. The methodology was found to be efficient for the discrimination between specimens coming from the same source and specimens coming from different sources. The results highlighted the practical utility of the chemical profiling, especially for supporting the investigation through operational intelligence and improving the knowledge related to the cocaine trafficking through strategic intelligence. © 2015 Elsevier Ireland Ltd.
Pratt A.,Forensic Laboratory
Journal of Forensic Identification | Year: 2012
Data referencing the number of identifiable latent prints developed on firearms evidence over a three-year period was collected. The results showed a recovery rate of 13% on firearms and 7.6% on ammunition magazines. Factors that play a role in the recovery of identifiable latent prints are discussed.
Mitchell A.,Forensic Laboratory
Journal of Forensic Sciences | Year: 2012
Microscopic analysis for the identification of spermatozoa is commonly performed during the forensic examination of sexual assault evidence. Two widely utilized methods for the confirmation of the presence of spermatozoa are visualization of the cells via phase-contrast microscopy with wet mounted samples and bright field microscopy with histologically stained samples. The KPICS SpermFinder™ by NicheVision Forensics, LLC accelerates this time-consuming process via an automated microscope with an algorithm designed to locate spermatozoa on a Christmas tree histologically stained microscope slide. Upon a qualified scientist's review of the generated data, the KPICS SpermFinder™ was able to locate spermatozoa, typically finding on average 106.28%±115.37% more spermatozoa than with manual examinations. The KPICS SpermFinder™ provided the location of identified cells with reproducible results. 2012 American Academy of Forensic Sciences. Published 2012. This article is a U.S. Government work and is in the public domain in the U.S.A.
Snyder C.,Forensic Laboratory
Journal of Forensic Identification | Year: 2015
Seven different sandy soils were utilized to create three-dimensional footwear impressions from two athletic shoes (Saucony and New Balance). The footwear impressions were photographed and cast with dental stone. The impressions made in the fill dirt and the yellow builders sand retained the most randomly acquired characteristics. The impressions made in the Astatula fine sand and the crushed coquina retained the least randomly acquired characteristics. The results indicated that (1) soils with larger particles or very fine sand may retain less randomly acquired characteristics (fine detail) than other sandy soils, thus affecting the ability of the impression to retain good detail; (2) soils with higher clay or organic contents will retain more randomly acquired characteristics; and (3) impressions located in a variety of sandy soil types have the ability to retain a sufficient number of randomly acquired characteristics to effect an identification.
Luostarinen T.,Forensic Laboratory |
Lehmussola A.,Forensic Laboratory
Journal of Forensic Sciences | Year: 2014
Shoeprints are an important source of information for criminal investigation. Therefore, an increasing number of automatic shoeprint recognition methods have been proposed for detecting the corresponding shoe models. However, comprehensive comparisons among the methods have not previously been made. In this study, an extensive set of methods proposed in the literature was implemented, and their performance was studied in varying conditions. Three datasets of different quality shoeprints were used, and the methods were evaluated also with partial and rotated prints. The results show clear differences between the algorithms: while the best performing method, based on local image descriptors and RANSAC, provides rather good results with most of the experiments, some methods are almost completely unrobust against any unidealities in the images. Finally, the results demonstrate that there is still a need for extensive research to improve the accuracy of automatic recognition of crime scene prints. © 2014 American Academy of Forensic Sciences.