Folkha lsan Research Center

Helsinki, Finland

Folkha lsan Research Center

Helsinki, Finland
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Jorgensen M.S.,Technical University of Denmark | Arsky G.H.,BAMA Gruppen AS | Brandhoj M.,University of Aalborg | Nyberg M.,Kristianstad University College | And 2 more authors.
International Journal of Workplace Health Management | Year: 2010

Purpose - The purpose of this paper is to review national experiences and policy initiatives within worksite eating in four Nordic countries, in order to compare the experiences and identify important lessons and needs for future research, experiments and governmental regulation. Design/methodology/approach - The paper is based on national reviews of analyses of worksite eating and initiatives regarding policy, research and experiments in relation to worksite eating. The national experiences are compared. Findings - The paper shows awareness in all four countries about the role of the worksite in the shaping of dietary habits of the employees and some experiments with healthier worksite eating schemes. Blue-collar employees, employees with working hours outside normal working hours and employees with shifting worksites are likely to be offered less organised and less healthy food schemes. Worksites' experiments with healthier worksite eating schemes based on employee participation can change worksite eating substantially, including at blue-collar worksites. However, the generalising of findings to other worksites not participating in the experiments seems limited. There is need for more research in the embedding of experiments. Originality/value - The paper has value as the first cross-national review covering four of the Nordic countries in the area of worksite eating and attempts to create healthier worksite eating. By combining research findings and policy initiatives from four countries, the paper gives access to a big pool of knowledge, which can inspire future research and policy initiatives, including future experiments and future governmental regulation. Copyright © Emerald Group Publishing Limited.

Reiling E.,National Institute for Public Health and the Environment RIVM | Lyssenko V.,Skåne University Hospital | Boer J.M.A.,National Institute for Public Health and the Environment RIVM | Imholz S.,National Institute for Public Health and the Environment RIVM | And 7 more authors.
European Journal of Human Genetics | Year: 2012

p53 is involved in stress response, metabolism and cardiovascular functioning. The C-allele of rs1042522 in the gene encoding for p53 is associated with longevity and cancer. In this study, we aimed to investigate the association of rs1042522 with changes in blood pressure, BMI and waist circumference using a longitudinal approach. Rs1042522 was analyzed in two longitudinal studies; the Doetinchem Cohort Study (DCS) and the Botnia Prospective Study (BPS). Changes in quantitative traits over time were investigated according to rs1042522 genotypes. An association between rs1042522 and changes in diastolic blood pressure (DBP) in the DCS over time was observed (P=0.004). Furthermore, a borderline significant association was detected with changes in waist circumference over time (P=0.03). These findings were also observed in the BPS (P=0.02 and P=0.05). The C/C-genotype (Pro/Pro) showed the most moderate time-related increase for the studied endpoints. Furthermore, data from the BPS suggested that the C/C-genotype protects against increases in glucose levels over time at 30 and 60 min during oral glucose tolerance test (P=0.01 and P=0.02). In conclusion, we found an association between the C/C-genotype of rs1042522 and changes in DBP and waist circumference over time. This might contribute to the longevity phenotype observed for the same genotype by others. © 2012 Macmillan Publishers Limited All rights reserved.

Yang H.P.,U.S. National Cancer Institute | Cook L.S.,University of New Mexico | Weiderpass E.,Karolinska Institutet | Weiderpass E.,Folkha Lsan Research Center | And 35 more authors.
British Journal of Cancer | Year: 2015

Background: Nulliparity is an endometrial cancer risk factor, but whether or not this association is due to infertility is unclear. Although there are many underlying infertility causes, few studies have assessed risk relations by specific causes.Methods:We conducted a pooled analysis of 8153 cases and 11 713 controls from 2 cohort and 12 case-control studies. All studies provided self-reported infertility and its causes, except for one study that relied on data from national registries. Logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI).Results:Nulliparous women had an elevated endometrial cancer risk compared with parous women, even after adjusting for infertility (OR=1.76; 95% CI: 1.59-1.94). Women who reported infertility had an increased risk compared with those without infertility concerns, even after adjusting for nulliparity (OR=1.22; 95% CI: 1.13-1.33). Among women who reported infertility, none of the individual infertility causes were substantially related to endometrial cancer.Conclusions:Based on mainly self-reported infertility data that used study-specific definitions of infertility, nulliparity and infertility appeared to independently contribute to endometrial cancer risk. Understanding residual endometrial cancer risk related to infertility, its causes and its treatments may benefit from large studies involving detailed data on various infertility parameters. © 2015 Cancer Research UK. All rights reserved.

Komulainen E.,University of Helsinki | Meskanen K.,University of Helsinki | Lipsanen J.,University of Helsinki | Lahti J.M.,University of Helsinki | And 8 more authors.
PLoS ONE | Year: 2014

Personality features are associated with individual differences in daily emotional life, such as negative and positive affectivity, affect variability and affect reactivity. The existing literature is somewhat mixed and inconclusive about the nature of these associations. The aim of this study was to shed light on what personality features represent in daily life by investigating the effect of the Five Factor traits on different daily emotional processes using an ecologically valid method.The Experience Sampling Method was used to collect repeated reports of daily affect and experiences from 104 healthy university students during one week of their normal lives. Personality traits of the Five Factor model were assessed using NEO Five Factor Inventory. Hierarchical linear modeling was used to analyze the effect of the personality traits on daily emotional processes. Neuroticism predicted higher negative and lower positive affect, higher affect variability, more negative subjective evaluations of daily incidents, and higher reactivity to stressors. Conscientiousness, by contrast, predicted lower average level, variability, and reactivity of negative affect. Agreeableness was associated with higher positive and lower negative affect, lower variability of sadness, and more positive subjective evaluations of daily incidents. Extraversion predicted higher positive affect and more positive subjective evaluations of daily activities. Openness had no effect on average level of affect, but predicted higher reactivity to daily stressors. The results show that the personality features independently predict different aspects of daily emotional processes. Neuroticism was associated with all of the processes. Identifying these processes can help us to better understand individual differences in daily emotional life. ©2014 Komulainen et al.

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