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Mangalore, India

Asish J.,Sree Gokulam Medical College | Amar M.,Chalmida Anand Rao Institute of Medical science | Hajare V.,Navodaya Medical College | Sreekantha S.,Navodaya Medical College | And 2 more authors.
International Journal of Pharma and Bio Sciences | Year: 2013

Chronic suppurative otitis media(CSOM) has been a source of a tremendous health predicament since time immemorial and even today it is immensely intricate. It is an important cause of hearing impairment which in turn may cause serious long term effect on language, auditory and cognitive development and on educational development.Knowledge of the prevailing flora and their susceptibility to antimicrobials will guide the clinician as to prescribing an empirical regimen so that a better and more specific management can be provided to the patients. Hence this study is done in present secenario to isolate the organims associated with CSOM and its susceptibility pattern. To identify the bacterial and fungal profile of Chronic Suppurative Otitis Media patients. 120 patients attending ENT OPD in Navodaya Medical College Hospital and Research Centre were analysed from Nov 2009 to Oct 2010. Using predefined inclusion and exclusion criteria, samples were obtained using sterile cotton microswabs. These were cultured for microbial flora and were identified. Drug susceptibility was done using Kirby Bauer disc diffusion method. The most common organism isolated was Pseudomonas aeruginosa 33% followed by Staphylococcus aureus 25.8% among the 91 bacterial isolates. This was followed by Proteus mirabilis 20.6%, Enterobacter aerogenes and Streptococcus spp at 4.1%. The organisms were most prevalant in winter and early spring between Nov- Feb. Also maximum number of cases were seen in age group of 21-30 years. The organisms were sensitive to gatifloxacin, cefoperazone sulbactum and ceftriaxone.Fungal isolates accounted for 6.2% of the organism with Aspergillus flavus 3.1%, Aspergillus niger 2.1% and Candida albicans 1%. The study suggests that Pseudomonas aeruginosa and Staphylococcus aureus are the most common etiological agents of CSOM. Most of the strainwere sensitive to fluoroquinolones and cephalosporins.

Basavaraj,Navodaya Medical College | Sreekantha,Navodaya Medical College | Shepur T.A.,Korea Institute of Materials Science | Nandi S.V.,Navodaya Medical College | And 2 more authors.
International Journal of Pharma and Bio Sciences | Year: 2012

Objective: To study the prevalence of intestinal parasitic infestations in HIV seropositive children and to correlate these infestations with different immunological status and WHO clinical staging. Methods: Three consecutive samples of each 60 HIV seropositive children in the age group of 18 months to 15 years admitted in KIMS, Hubli, Karnataka, over a period of one year from 1st November2007 to 31st October 2008, were tested for intestinal parasites in the Microbiology department, KIMS, Hubli. Results: The overall prevalence of intestinal parasitic infestation found in this study was 35% (21/60 cases). Of 21 cases, 17 were seen in patients with severe immune suppression. Most of the intestinal parasitic infestations were seen in patients with diarrhea (16/28) cases compared to patients without diarrhea (5/32) cases. The most frequently detected intestinal parasite in this study was Balantidium Coli, followed by Ascaris lumbricoides, Trichuris trichura, Cryptosporidia, Hymenolepiasis nana, Strongyloides stercoralis, Enterobius vermicularis. One case of multiple intestinal parasitic infestations was also noted in this study. Conclusion: The present study highlights the magnitude of intestinal parasitic infestation HIV infected children. The prevalence was found to be significantly more in patients with diarrhea than without diarrhea. Most of the intestinal parasitic infestations were seen in severely immunosuppressed children. However, parasites were also observed in other immune suppression group. So intestinal parasitic infestation should be suspected in all HIV seropositive children particularly with diarrhea and severe immune suppression.

Yogender P.,NMC | Sujatha R.,Shri Sathya Sai Medical College | Rangaswamy R.,Kempegowda Institute of Medical science | Sreekantha,NMC | Avinash S.S.,FMMC
Research Journal of Pharmaceutical, Biological and Chemical Sciences | Year: 2014

Anemia is widely prevalent in India which consists of 80% of villages in India, where Majority of the people is ignorant of the hemopoietic principles of diet belong to low socioeconomic status. Pregnancy Imposes an extra demand on the the nutrients, hence anemia is rather a constant association. Factors such as food which is chiefly derived from local ingredients and secondly prevalence of parasitic infections varies and therefore the pattern of incidence, severity and type of anemia also alters. Anemia in pregnancy is a major public health problem in the developing countries. It is one of the commonest causes of the high maternal mortality rate. It is also responsible for the high incidence of premature and low birth of premature and low birth weight babies, thus increasing the perinatal mortality and morbidity. This study deals with various types of anaemia in pregnant women having Haemoglobin level less than 11gm% and study sensitivity and positive predictive value of Red cell distribution width in diagnosis of Iron deficiency anaemia.

Aramani A.,Nose and Throat | Karadi R.N.,Shri Bmpatil Medical College | Kumar S.,FMMC
Journal of Clinical and Diagnostic Research | Year: 2014

Background: Chronic rhino sinusitis(CRS) is the most common disease for which consultation of otorhinolaryngologist is sought. The approach to patients with chronic rhino sinusitis is endoscopic surgery which aims at removing the obstruction of the main drainage pathway. The osteomeatal complex based essentially on the concept that such obstruction perpetuates the sinus disease. This in turn requires the surgeons to have detailed knowledge of the anatomy of the lateral nasal wall, paranasal sinuses and surrounding vital structures and of the large number of anatomical variants in the region.Aims: To study anatomical variations of osteomeatal complex in chronic sinusitis patients.Materials and Methods: Descriptive Cross sectional study design in which fifty four consecutive cases of chronic rhino sinusitis patients attending the ENT outpatient department, who had chronic sinusitis for more than three months duration not responding to the medical line of treatment and who were willing to undergo Functional Endoscopic Sinus Surgery satisfying the inclusion criteria were studied. The results were expressed in percentage and proportions.Results: In our study it was observed that 53.7% of the chronic sinusitis cases had two or more anatomical variations and 33.3% of the cases had single anatomical variation. Deviated nasal septum was found to be the most common amongst the anatomical variations in chronic sinusitis cases in the present study which was followed by unilateral concha bullosa and paradoxically bent middle turbinate. Agger nasi cell and Haller cell were seen in one case each.Conclusion: Prevalence of multiple anatomical variations was more in our study in comparison to single anatomical variation. Deviated nasal septum was the most common anatomical variation encountered in our study followed by concha bullosa. © 2014, Journal of Clinical and Diagnostic Research. All rights reserved.

Avinash S.S.,FMMC | Sreekantha,NMC | Remya,NITTE University | Vinodchandran,Manipal University India
International Journal of Pharma and Bio Sciences | Year: 2014

Dermatoglyphics is influenced by heredity and abnormality in it are associated with chromosomal anamolies. Primary hypertension is polygenic and the scientific dermatoglyphic pattern analysis are rare, which could be used as a diagnostic and screening aid. The present was done to study the frequency distribution of scientific ridge pattern in primary hypertensives. The study was carried out in 200 primary hypertensives with 200 normal controls. The hand imprinting was done using a slight modification of conventional ink flab method. Data were analysed using t test. The primary hypertensive male and female had significantly high frequency of whorls and TFRC and decreased ulnar loops and "atd" angle in both hands. Dermatoglyphics can be considered as a simple, inexpensive aid for screening and diagnosing primary hypertension.

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